The landmark text that belongs in the hands of every cardiologist?fully updated and reorganized to make it more patient-centric than ever



World-famous for its authority and clinical relevance, Fuster and Hurst's The Heart is cardiology's longest continuously published reference book. Written to meet the ever-changing needs of cardiologists, fellows, and interns, this trusted classic offers a solid foundation in cardiovascular medicine and complete coverage of all major cardiovascular topics.



This fifteenth edition presents a greater focus on the practicalities of patient care. Additionally, the content is ordered in a more methodical pattern, from mechanism to management. Reflecting the latest technical, therapeutic, and clinical advances, Fuster and Hurst's The Heart provides invaluable concise summaries of major new trials and guidelines.



Authoritative Coverage and Unmatched Utility:

Central Illustrations
New section on cardiovascular critical care
New chapter "Cardiovascular Disease and COVID-19"
Chapter summaries
ACC/AHA/ESC guidelines in all chapters
1,200+ photos and illustrations

Sections Include:

Risk Factors for Cardiovascular Disease
Atherosclerosis and Coronary Heart Disease
Diseases of the Great Vessels and Peripheral Vessels
Valvular Heart Disease
Rhythm and Conduction Abnormalities
Heart Failure
Diseases of the Pericardium
Cardiopulmonary Disease
Critical Cardiovascular Care
Adult Congenital Heart Disease
Special Populations and Topics in Cardiovascular Disease


SECTION I Introduction

1. The Global Burden ofCardiovascular Diseases

Catherine P. Benziger, Andrew E. Moran,Gregory A. Roth, and George A. Mensah

2.Clinical Cardiovascular Examination

William R. Miranda and Rick A. Nishimura

3.Cardiovascular Imaging Techniques

Thomas H. Marwick and Jagat Narula

4.Genomics and Epigenomics of Heart Diseases

June-Wha Rhee and Joseph C. Wu



SECTION II Risk Factors for Cardiovascular Disease

5.Epidemiology, Pathophysiology, and Treatment of Hypertension

Michael E. Hall, John E. Hall, and Paul K.Whelton

6.Cardiometabolic Disease: Insulin Resistance, Obesity, and the MetabolicSyndrome

W. Timothy Garvey and Jeffrey I. Mechanick

7.Diabetes and Cardiovascular Disease

Jeffrey I. Mechanick and Michael E. Farkouh

8.Tobacco-Related Cardiovascular Disease

Nancy A. Rigotti, Sara Kalkhoran, and NealL. Benowitz

9.Air Pollution and Cardiovascular Disease

Michael B. Hadley and Sanjay Rajagopalan

10.Hypercholesterolemia, Hyperlipoprotein(A), Hypertriglyceridemia, and Low HDL

Robert S. Rosenson, Marlys L. Koschinsky,B rge G. Nordestgaard, and Robert A. Hegele

11.Psychological Factors in Cardiovascular Health and Disease

Darwin R. Labarthe and Rosalba Hernandez

12.Sedentary Lifestyle and Role of Exercise in Cardiovascular Diseases

Ambarish Pandey, Nitin Kondamudi, and CarlJ. Lavie

13.Nutrition, Diet, and Alcohol in Health and Cardiovascular Disease

Marta Guasch-Ferré and Frank Hu

14.Inflammation and Atherosclerosis

Hasan K. Siddiqi and Paul M. Ridker

15.Location and Level of Care, Education, Availability of Medicines, andCardiovascular Mortality

Rajeev Gupta, Philip Joseph, AnnikaRosengren, and Salim Yusuf



SECTION III Atherosclerosis and Coronary Heart Disease

16.Pathology and Pathogenesis of Atherosclerosis and its Progression

Jagat Narula, Erling Falk, and ValentinFuster

17.Pathogenesis of Coronary Thrombosis and Myocardial Infarction

Gemma Vilahur, Valentín Fuster, and BorjaIbanez

18.ST-Elevation Myocardial Infarction (STEMI)

Borja Ibanez, Manesh Patel, InésGarcía-Lunar, Usman Baber, Jonathan Halperin, and Valentin Fuster

19.Evaluation and Management of Non ST-Segment Elevation Acute Coronary Syndromes

Eric R. Bates, David J. Moliterno, andManesh R. Patel

20.Mimickers of Atherosclerotic Myocardial Infarction: SCAD, Coronary Vasospasm,Myocarditis, and Takotsubo Syndrome

Jacqueline Saw, Jaya Chandrasekhar, SarahZaman, and Harmony Reynolds

21.Chronic Coronary Syndromes

Sripal Bangalore, Ziad Ali, Jagat Narula,John Puskas, and Gregg W. Stone

22.Cardiac Rehabilitation: Current Practice and Future Directions

Alan Rozanski, Saman Setareh-Shenas, andJagat Narula



SECTION IV Diseases of the Great Vessels and Peripheral Vessels

23.Diseases of the Aorta

John A. Elefteriades, Bulat A. Ziganshin,and Jonathan L. Halperin

24.Carotid Artery Disease

Christopher J. White

25.Cerebrovascular Disease

Hugo J. Aparicio, Vasileios Lioutas, ThanhN. Nguyen, and Sudha Seshadri

26.Diagnosis and Management of Diseases of the Peripheral Arteries

Hillary Johnston-Cox, Daniella Kadian-Dodov,and Jeffrey W. Olin



SECTION V Valvular Heart Disease

27.Acute Rheumatic Fever

Liesl Zühlke, Jagat Narula, Mark Engel, andJonathan R. Carapetis

28.Aortic Stenosis

Marie-Annick Clavel, Marc R. Dweck, Martin Leon,and Philippe Pibarot

29.Aortic Regurgitation, Mixed Valvular Heart Disease, and Heart Valve Prostheses

Patrizio Lancellotti, Alexandra Chitroceanu,Simona Sperlongano, Raluca Dulgheru, and Adriana Postolache

30.Mitral Regurgitation

Jeroen J. Bax, Nina Ajmone Marsan, Pietervan der Bijl, Hendrik Treede, Michele DeBonis, Bernard Prendergast, BernardIung, and Victoria Delgado

31.Acquired Tricuspid Valve Diseases

Luigi P. Badano, Ana Pardo, Denisa Muraru,and Jose Louis Zamorano

32.Mitral Stenosis

Vinay K. Bahl and Ravi S. Math

33.Infective Endocarditis

Ann F. Bolger



SECTION VI Rhythm and Conduction Abnormalities

34.Electrophysiologic Anatomy, Mechanisms of Arrhythmias and ConductionDisturbances, and Genetics

Peng-Sheng Chen, MD, Siew Yen Ho, Silvia G.Priori, and Charles Antzelevitch

35.Supraventricular Tachycardia: Atrial Tachycardia, Atrioventricular NodalReentry, and Wolff-Parkinson-White Syndrome

David Spragg and Hugh Calkins

36.Atrial Fibrillation and Atrial Flutter

Anne B. Curtis, Tina Baykaner, and Sanjiv M.Narayan

37.Ventricular Arrhythmias and Sudden Cardiac Death

Justin Hayase, Kalyanam Shivkumar, and JasonS. Bradfield

38.Conduction System Disturbances and Bradyarrhythmias

Pugazhendhi Vijayaraman, Jeffrey Arkles,Jayanthi N. Koneru, and David J. Callans

39.Diagnosis and Management of Syncope

Zachary D. Goldberger, Mohammed Ruzieh, andBlair P. Grubb



SECTION VII Heart Failure

40.Classification of Cardiomyopathies

Eloisa Arbustini, Barry J. Maron, NavneetNarula, and Jagat Narula

41.Dilated Cardiomyopathy

Eloisa Arbustini, Alessandro Di Toro,Lorenzo Giuliani, Mario Urtis, G. William Dec, and Jagat Narula

42.Hypertrophic Cardiomyopathy

Massimiliano Lorenzini and Perry M. Elliott

43.Cardiac Amyloidosis

Morie A. Gertz, Jagat Narula, EdgarArgulian, and Sumeet S. Mitter

44.Restrictive Heart Diseases

Eloisa Arbustini, Alessandro Di Toro,Lorenzo Giuliani, G. William Dec, and Jagat Narula

45.Left Ventricular Noncompaction

Eloisa Arbustini, Alessandra Serio, LorenzoGiuliani, Nupoor Narula, and Alessandro Di Toro

46.Myocarditis

Eloisa Arbustini, Alessandro Di Toro, MarioUrtis, Sean Pinney, and Jagat Narula

47.Obstructive and Nonobstructive Coronary Disease in Heart Failure

Charlotte Lee and G. William Dec

48.Diagnosis and Management of Chronic Heart Failure

Muhammad Shahzeb Khan, Muthiah Vaduganathan,and Javed Butler

49.Diagnosis and Management of Heart Failure With Preserved Ejection Fraction

Jo o Pedro Ferreira, Kavita Sharma, andJaved Butler

50.Evaluation and Management of Acute Heart Failure

Kiran Mahmood, Eric J. Velazquez, andAnuradha Lala

51.Peripartum Cardiomyopathy

Uri Elkayam and Jena Pizula

52.Surgical Management of the Severe Heart Failure Patient: Mechanical CirculatorySupport and Heart Transplantation

Adam D. DeVore, Michelle M. Kittleson,Carmelo A. Milano, Jignesh K. Patel, Joseph G. Rogers, and Jon A. Kobashigawa



SECTION VIII Diseases of the Pericardium

53.Acute Pericarditis

James W. Lloyd, Sushil Allen Luis, Zi Ye,and Jae K. Oh

54.Percardial Effusion and Tamponade

Darryl J. Burstow, Sushil Allen Luis, GarvanC. Kane, and Jae K. Oh

55.Constrictive Pericarditis

William R. Miranda, Kevin L. Greason, JohnM. Stulak, and Jae K. Oh



SECTION IX Cardiopulmonary Disease

56.Diagnosis and Management of Diseases of the Peripheral Venous System

Daniella Kadian-Dodov, Hillary Johnston-Cox,and Jeffrey W. Olin

57.Pulmonary Hypertension

Yogesh N. V. Reddy and Barry A. Borlaug

58.Pulmonary Embolism

Victor F. Tapson

59.Cor Pulmonale: The Heart in Structural Lung Disease

Lewis J. Rubin

60.Sleep-Disordered Breathing

Shahrokh Javaheri , Dirk Pevernagie, and AliJavaheri



SECTION X Critical Cardiovascular Care

61.Evolution of Cardiac Critical Care

Venu Menon and Penelope Rampersad

62.Circulatory and Cardiogenic Shock

Gregory Serrao, Benjamin Bier, and UmeshGidwani

63.Sudden Cardiac Death and Resuscitation

Sanjiv M. Narayan and James P. Daubert

64.Postoperative and Postprocedural Care in the Cardiac Intensive Care Unit

Venu Menon



SECTION XI Adult Congenital Heart Disease

65.Anatomical and Physiological Classification of Adult Congenital Heart Disease

Jasmine Grewal and Alexander R. Opotowsky

66.Shunt Lesions

Ari M. Cedars, Shelby Kutty, and AshishDoshi

67.Right-Sided Lesions

Konstantinos Dimopoulos and AndrewConstantine

68.Left Heart Obstructive Lesions

Jennifer Cohen, David Ezon, Kenan Stern, andAli N. Zaidi

69.Single Ventricle Post Fontan Palliation: Tricuspid Atresia, Pulmonary Atresia,and Hypoplastic Left Heart Syndrome

Marie-A Chaix and Paul Khairy

70.Complex Cyanotic Congenital Heart Disease: The Mixing Lesions

Rafael Alonso-Gonzalez and DanielleMassarella

71.Psychosocial Profiles in Adult Congenital Heart Disease and Transition toAdulthood

Philip Moons



SECTION XII Special Populations and Topics in Cardiovascular Disease

72.Perioperative Evaluation for Noncardiac Surgery

Daniel Alyesh, Prashant Vaishnava, and KimA. Eagle

73.Anesthesia and the Patient with Cardiovascular Disease

David L. Reich, Elvera L. Baron, and Joel A.Kaplan

74.Cardiovascular Disease in Patients With Cancer and Cardiovascular Complicationsof Cancer Therapies

Edward T. H. Yeh

75.Heart Disease in Chronic Kidney Disease

Jared Hooker, Omar Baber, and Usman Baber

76.Rheumatologic Disease and the Cardiovascular System

Emily Carroll and Yousaf Ali

77.Cardiovascular Disease in Patients with HIV

Pravin Manga, Keir McCutcheon, and Nqoba Tsabedse

78. Heart Disease inPregnancy

Dan G. Halpern, Amy Sarma, Katherine E.Economy, and Anne Marie Valente

79.Traumatic Heart Disease

T. Bruce Ferguson, Jr, Austin Rogers, andRobert Allman

80.Women and Ischemic Heart Disease: An Evolution in Knowledge

Leslee J. Shaw, Viviany R. Taqueti, andNanette K. Wenger

81.Race, Ethnicity, Disparities, and Diversity: The Intersection With HeartDisease

Clyde W. Yancy

82.Cardiovascular Disease and Ageing: Cellular and Molecular Mechanisms

Zoltan Ungvari, Dao-Fu Dai, Bela Merkely,and Anna Csiszar

83.Artificial Intelligence and Cardiovascular Care

John S. Rumsfeld, Bobak J. Mortazavi, andHarlan M. Krumholz

84.Cardiovascular Manifestations of COVID-19

Sean P. Pinney, Gennaro Giustino, andJeffrey I. Mechanick