This interdisciplinary book is one of the first practical guides to imaging children with PET. Heavily illustrated, the book provides the reader with key information on technical and clinical issues specific to pediatric PET imaging. Special considerations regarding radiation dosage and sedation, principles of operation, instrumentation, and nuclear medicine regulations are discussed. Subsequent sections present diseases and clinical applications of PET in pediatrics. The discussions are based an exhaustive review of pediatric PET studies by Martin Charron, MD, and a select group of leading international authorities. The scope of pathologies addressed is extensive. Applications in oncology, neurology, psychiatry and other fields are outlined. Future research applications are offered as well. The book not only covers dedicated PET imaging, but also integrates coincidence imaging, PET/CT, and PET/MR. This thorough text is a vital aid to nuclear medicine physicians, radiologists, and oncologists seeking to successfully apply recent innovations in pediatric PET imaging.

Table of contents (31 chapters)
The Nuclear Imaging Technologist and the Pediatric Patient

Green, Maria

Pages 3-20
Sedation of the Pediatric Patient

Kaye, Robin

Pages 21-29
The Biologic Effects of Low-Level Radiation

Charron, Martin

Pages 30-36
Dosage of Radiopharmaceuticals and Internal Dosimetry

Zhu, Xiaowei

Pages 37-46
Pediatric PET Research Regulations

Levine, Geoffrey

Pages 47-58
Issues in the Institutional Review Board Review of PET Scan Protocols

Nelson, Robert M.

Pages 59-71
Ethics of PET Research in Children

Munson, Suzanne (et al.)

Pages 72-91
Physics and Instrumentation in PET

Accorsi, Roberto (et al.)

Pages 92-120
How to Image a Child by PET Computed Tomography

Kaste, Sue C. (et al.)

Pages 121-134
Coincidence Imaging

Bal, Girish (et al.)

Pages 135-171
Brain Tumors

Fisher, Michael J. (et al.)

Pages 173-219
Lymphoma

Palestro, Christopher J. (et al.)

Pages 220-242
Neuroblastoma

Shulkin, Barry L.

Pages 243-255
Wilms' Tumor

Kaste, Sue C. (et al.)

Pages 256-266
Primary Bone Tumors

Howman-Giles, Robert (et al.)

Pages 267-301
Soft Tissue Sarcomas

Hickeson, Marc P.

Pages 302-311
Other Tumors

Yu, Jian Qin (et al.)

Pages 312-320
The Developing Brain

O'Tuama, Lorcan A. (et al.)

Pages 323-333
Neurodevelopmental and Neuropsychiatric Disorders

Glanzman, Marianne (et al.)

Pages 334-360
Epilepsy

Bohnen, Nicolaas I. (et al.)

Pages 361-384
Neurotransmitter Imaging

Fischman, Alan J. (et al.)

Pages 385-403
Cardiovascular Applications

Hernandez-Pampaloni, Miguel

Pages 405-427
Fever of Unknown Origin

Zhuang, Hongming (et al.)

Pages 428-447
Infection and Inflammation

Hickeson, Marc P.

Pages 448-460
Inflammatory Bowel Disease

Alberini, Jean-Louis (et al.)

Pages 461-471
Hyperinsulinism of Infancy: Noninvasive Differential Diagnosis

Santiago-Ribeiro, Maria-Jo o (et al.)

Pages 472-478
Hyperinsulinism of Infancy: Localization of Focal Forms

Hardy, Olga T. (et al.)

Pages 479-484
Multimodal Imaging Using PET and MRI

Pfluger, Thomas (et al.)

Pages 485-501
Current Research Efforts

Ponzo, Fabio (et al.)

Pages 502-524
PET-Computed Tomography Atlas

McCarville, M. Beth

Pages 525-542
Common Artifacts on PET Imaging

Bhargava, Peeyush (et al.)