This book provides state of the art knowledge on a broad range of clinical issues in pancreatic cancer, covering topics from screening and pathophysiology to surgical treatments. In particular, the focus is on current controversies and on evidence-based surgical techniques. Further aspects considered include the management of precancerous lesions, diagnostic methods, perioperative care and nonsurgical treatment. The description of surgical methods is supported by many helpful illustrations and important technical issues are carefully addressed. Determination of resectability and extent of surgery is also discussed. Based on recent developments in surgical techniques, some surgeons are performing more and more radical operations. It is essential, however, that surgical strategy is based on the best available evidence and surgeons will find that this book offers valuable help in achieving this aim. In addition, it will be a great asset in clinical practice for all who are involved or interested in the management of pancreatic cancer.

Table of contents (41 chapters)
Epidemiology
Won, Young-Joo
Pages 3-9
Molecular Alterations in Pancreatic Cancer
Furukawa, Toru
Pages 11-23
Pathological Classification
Xue, Yue (et al.)
Pages 25-51
Controversial Issues in Pathological Diagnosis
Yanagisawa, Akio
Pages 53-65
Operative Specimen Handling and Evaluation of Resection Margins
Verbeke, Caroline Sophie
Pages 67-87
Tumor Markers
Ryu, Ji Kon
Pages 89-92
Imaging Diagnosis of Pancreatic Cancer: CT and MRI
Lee, Jeong Min (et al.)
Pages 95-114
Endoscopic Diagnosis
Itoi, Takao (et al.)
Pages 115-121
PET and Other Functional Imaging
Kang, Keon Wook
Pages 123-129
Staging and Determination of Resectability of Pancreatic Cancer
Miyazawa, Motoki (et al.)
Pages 133-138
Current Issues of Borderline Resectable Pancreatic Ductal Adenocarcinoma
Denbo, Jason W. (et al.)
Pages 139-149
Guidelines for the Management of Pancreatic Cystic Neoplasms
Tanaka, Masao
Pages 151-159
Guideline for the Management of Pancreatic Neuroendocrine Tumor
Spoletini, Gabriele (et al.)
Pages 161-172
The History and Evolution of Pancreaticoduodenectomy
Griffin, James F. (et al.)
Pages 175-183
Major Vascular Resection in Pancreatic Carcinoma
Karstens, Karl-Frederick (et al.)
Pages 185-192
Retroperitoneal Nerve Plexus Dissection During Pancreatoduodenectomy
Fujii, Tsutomu (et al.)
Pages 193-200
Mesenteric Approach for Pancreaticoduodenectomy
Hirono, Seiko (et al.)
Pages 201-206
Artery-First Approach for Pancreatic Cancer
Pandanaboyana, Sanjay (et al.)
Pages 207-213
Mesopancreas Excision for Pancreatic Cancer
Inoue, Yosuke (et al.)
Pages 215-223
Concepts in Isolated Pancreatectomy for Pancreatic Cancer Using the Nakao Mesenteric Approach and Catheter Bypass of the Portal Vein
Nakao, Akimasa
Pages 225-230
Role of Extended Resection in Pancreatic Cancer
Jang, Jin-Young
Pages 231-238
Type of Reconstruction After Pancreatoduodenectomy
Shyr, Yi-Ming (et al.)
Pages 239-246
The Concept of Customized Pancreatoduodenectomy
Kim, Sun-Whe
Pages 247-260
Distal Pancreatectomy with En Bloc Celiac Axis Resection (DP-CAR) for Advanced Pancreatic Body Cancer
Hirano, Satoshi
Pages 261-267
Radical Antegrade Modular Pancreato-splenectomy (RAMPS)
Grossman, Julie G. (et al.)
Pages 269-280
Laparoscopic Distal Pancreatectomy in Pancreatic Cancer
Han, Ho-Seong
Pages 281-284
Robotic Application for Pancreatectomy
Maggi, Jason C. (et al.)
Pages 285-293
Organ-Preserving Pancreatectomy
Kwon, Wooil (et al.)
Pages 295-304
Minimally Invasive Surgery for Pancreatic Cancer
Kim, Song Cheol (et al.)
Pages 305-313
Pancreatic Fistula
Pulvirenti, Alessandra (et al.)
Pages 317-327
Delayed Gastric Emptying
Tani, Masaji
Pages 329-334
Postoperative Bleeding
Choi, Dong Wook (et al.)
Pages 335-347
Rare Complications After Pancreatectomy
Yoon, Dong-Sup
Pages 349-356
Late Metabolic Complications After Pancreatectomy
Yoon, Yoo-Seok
Pages 357-364
Enhanced Recovery Program After Pancreatectomy
Park, Sang-Jae
Pages 365-376
Drain Management After Pancreatectomy
Kawai, Manabu (et al.)
Pages 377-384
Chemotherapy in the Management of Pancreatic Cancer
Chiang, Nai-Jung (et al.)
Pages 387-419
Radiation Therapy
Choi, Jinhyun (et al.)
Pages 421-436
Endoscopic Intervention
Moon, Sung-Hoon (et al.)
Pages 437-444
Personalized Peptide Vaccine for Advanced Pancreatic Cancer
Yutani, Shigeru (et al.)
Pages 445-451
Emerging New Treatment Modalities: Irreversible Electroporation
Martin, Robert C. G.