This book comprehensively summarizes the current state of knowledge on malignancies of the gastrointestinal tract. Dedicated organ-based chapters evaluate current treatments and management and provide information on incidence, etiology and biological characteristics. The state of the art in the radiologic and endoscopic staging of gastrointestinal malignancies is described, and guidance is offered on the role of interventional radiology and interventional gastroenterology in the treatment of these challenging tumors. In addition, the book explores novel and evolving treatments, including personalized systemic therapy and minimally invasive surgical and radiology techniques, and addresses patient-reported outcomes and survivorship challenges. It closes by discussing animal models of gastrointestinal malignancies and examining the significance of the Ras superfamily of GTPases. It will be of benefit to all surgeons, oncologists and other specialists who treat these malignancies, as well as to trainees looking to increase their understanding of the field.

CONTENTS:
1. Gastric and Small Bowel Tumors
2. Pathologic Features of Esophageal and Gastric Malignancies
3. Pathologic Features of Miscellaneous Foregut Malignancies
4. Management Controversies and Treatment Strategies for Borderline Resectable Pancreatic Cancer
5. Pathologic Features of Primary Pancreatic Malignancies
6. Gall Bladder Cancer
7. Diagnosis and Management of Intrahepatic and Extrahepatic Cholangiocarcinoma
8. Hepatocellular Carcinoma: Surgical Management and Evolving Therapies
9. Clinical Features of Metastatic Hepatic Malignancies
10. Repeat Hepatectomy for Colorectal Liver Metastases
11. Minimally Invasive Surgery of the Liver
12. Locoregional Therapies for Primary and Secondary Hepatic Malignancies
13. Pathologic Features of Primary and Metastatic Hepatic Malignancies
14. Robotic Rectal Cancer Surgery
15. Pathologic Features of Primary Colon, Rectal, and Anal Malignancies
16. Importance of Adequate Lymphadenectomy in Gastrointestinal Cancer
17. Circulating Tumor Cells in Gastrointestinal Cancer: Current Practices and Future Directions
18. Cost-Effectiveness Analysis in Cancer Care
19. Gastrointestinal Malignancy: Genetic Implications to Clinical Applications