DESCRIPTION:
Principles and Applications of Therapeutic Ultrasound in Healthcare introduces concepts, principles, construction, and applications of therapeutic ultrasound: from bench to bedside. A comprehensive examination of the industry and medical application of ultrasound therapy, this book highlights working principles, research progress, and system structures of therapeutic ultrasound. It describes the principles of therapeutic ultrasound, details the system construction, introduces current and emerging applications, and discusses developing therapeutic ultrasound technologies.

Divided into two parts, the book first introduces the fundamentals of biomedical acoustics, discusses ultrasound calibration methods, and the structures of available therapeutic ultrasound systems before moving on to the various applications of ultrasound therapy used in clinics. It includes a variety of extensive clinical trials, outcome photos and illustrating figures, and a critical commentary on the challenges in this field.

The author discusses topics that include:
- The derivation of wave equation
- The mathematical solution of the wave propagation
- The phenomena of reflection
- Refraction and transmission in the acoustic field from different acoustic sources
- The radiation pattern of the ultrasound transducer
- The acoustical properties of biological tissues
- Ultrasound-induced bioeffects
- Cavitation
- The design of the ultrasound transducer
- The characterization method of the produced acoustic field

An easy reference offering full coverage of popular ultrasound therapies, Principles and Applications of Therapeutic Ultrasound in Healthcare provides a simple explanation of fundamental acoustics, including wave equation, propagation, nonlinearity, and transducer design. It also discusses other potential applications, and is geared toward academia, industry, and researchers.

CONTENTS:
Wave Equation
Fundamental Equations for an Ideal Fluid
Small-Amplitude 1D Acoustic Wave Equation
3D Wave Equation
Velocity Potential
Speed of Sound
Acoustic Impedance
Solution of Wave Equation
Spherical Waves
Cylindrical Waves
Wave in Solid
Assignment
References

Sound Reflection, Refraction, and Transmission
Acoustic Energy and Intensity
Sound Pressure and Intensity Level
Boundary Conditions
Normal Incidence
Oblique Incidence
Middle Layer Transmission
Assignment
References

Acoustic Field and Wave Radiation
Acoustic Interference
Acoustic Wave Radiation
Transducer Field
Array Transducer Field
Assignment
References

Acoustical Properties of Biological Tissue
Cell and Tissue
Acoustic Attenuation
Wave Equation with Attenuation
Viscosity Relaxation
Attenuation Measurement
Assignment
References

Nonlinear Acoustics
D Nonlinear Dynamic Equation
Nonlinear Equation of State
Nonlinearity Parameters
Nonlinear Acoustic Wave Propagation
Interaction of Finite-Amplitude Sound Waves
Interaction of Sources at Different Frequencies
Propagation of Finite-Amplitude Wave in Viscous Medium
Measurement of Nonlinearity B/A
Assignment
References

Cavitation
Nucleation
Cavitation Threshold
Rectified Diffusion
Bubble Dynamics
Cavitation Effects
Cavitation Measurement
References

Transducer
Piezoelectricity
Equivalent Circuit
Transducer Design
Capacitive Transducer
Transducer Array
References

Acoustic Field Calibration and Measurement
Acoustic Pressure Measurement
Radiation Force Balance
Calorimeter
Holography
Interferometric Measurement
Field Mapping Using Vibrometer
Schlieren Imaging
Light Diffraction Tomography
Light Scanning of Ultrasound Field
Time-Delay Spectrometry
Infrared Thermography
References

Ultrasonic Physiotherapy
Introduction
System Structure and Treatment Protocol
Mechanisms and Bioeffects
Clinical Trials
Discussion
References

Hyperthermia
Rationale of Hyperthermia
Effect of Thermal Conduction and Blood Perfusion
Ultrasound Hyperthermia Technology
Thermometry
Treatment Planning and Control
Ultrasound Hyperthermia-Induced Effects
Clinical Outcome
Combination with Radiation
Hyperthermia-Mediated Drug Release
Future Work
References

Shock Wave Lithotripsy and Treatment
Kidney Stone Disease and SWL History
Development
Limitations in Renal Injury and Stone Fragmentation
Technology and Measurement
Mechanisms of SWL: Stone Fragmentation and Renal Injury
Technical Improvement
Shock Wave Therapy
References

High-Intensity Focused Ultrasound
Introduction
History of HIFU
Advantages of HIFU
System Structure and Operation
Mechanism of HIFU
HIFU Monitoring and Control
Clinical Applications
Clinical Experience
HIFU-Related Therapeutic Methods
Conclusions
References

Ultrasound-Mediated Drug Delivery/Gene Transfection
Introduction
Drug/Gene Delivery Approach
Acoustically Active Drug Vehicles
Sonoporation
Targeted Drug Delivery for Cancer
Gene Therapy
Sonophoresis
Sonothrombolysis
Drug Delivery across the Blood-Brain Barrier (BBB)
Sonodynamic Therapy
Discussion and Future Directions
References