This fifth edition of a successful book provides an overview of fetal and perinatal pathology, concentrating on common problems, especially where the anatomical pathology findings guide the direction of further investigations.
A new feature of this edition is an emphasis on the molecular aspects of pathology in the perinatal setting. There are four new chapters, including one on the genetic and epigenetic basis of development and disease, and over 300 new illustrations. The format of the book remains the same as previous editions with the first half covering general areas in perinatal pathology. The second half is based on organ systems and covers specific pathological entities, now including discussion of the relevant molecular pathology. There is extensive cross-referencing between chapters.
Keeling's Fetal and Neonatal Pathology, 5th edition is aimed at the practising pathologist who is called upon to provide a perinatal pathology service. It is also a valuable resource for the pathology trainee and a reference for obstetricians, maternal and fetal medicine specialists, neonatologists, paediatricians and forensic pathologists.
Features
Explains the developmental basis of pathology seen in the perinatal period
Discusses the pathological basis of clinical outcomes
Provides a genetic overview of much of the normal development and pathology
Contents
The Perinatal Postmortem from a Clinician's Viewpoint.- The Perinatal Necropsy: Methodology.- Genetic and Epigenetic Basis of Development and Disease.- The Placenta and Umbilical Cord.- Perinatal Imaging.- Epidemiology of Fetal and Neonatal Death.- Pathology of Early Pregnancy Loss.- Congenital Abnormalities: Prenatal Diagnosis and Screening.- The Impact of Infection During Pregnancy on the Mother and Baby.- Perinatal Haematology.- Genetic Metabolic Disease.- Fetal Hydrops.- Pathology of Twinning.- Macerated Stillbirth.- Intrapartum Problems.- Prematurity.- Iatrogenic Disease.- Congenital Tumors.- The Cardiovascular System.- The Respiratory System.- The Alimentary Tract and Exocrine Pancreas.- Liver and Gallbladder.- The Urinary System.- The Reproductive System.- The Endocrine System.- The Reticuloendothelial System.- Brain Malformations.- Degenerative and Metabolic Brain Diseases.- Acquired Diseases of the Nervous System.- Skeletal Muscle and Peripheral Nerves.- The Skeletal System.- The Skin.- The Special Senses.- Forensic Aspects of Perinatal Pathology.