Adult hydrocephalus is an insidious yet treatable condition that develops slowly, with usual onset around 60 years of age. It is poorly recognized and many cases are not diagnosed until late in the course of disease, leading to poorer patient outcomes and a high financial cost to healthcare providers. The resulting neurological symptoms include gait/balance problems, loss of bladder control, and a cognitive decline leading to dementia, which is often mistaken for Alzheimer's disease. This book - the first published on this topic since 1993 - provides comprehensive guidelines to improve the speed and accuracy of diagnosis, and covers various neurosurgical techniques used to treat the disease, including the insertion of different types of shunts and endoscopic third ventriculostomy. This is essential reading for neurologists, neurosurgeons, family physicians, and radiologists who may well encounter adult patients with hydrocephalus more often than they realize.

Provides various treatment rationales helping readers to select the interventions that are least likely to cause complications in a specific patient
All of the chapters are written by leading global experts with a wealth of experience diagnosing and managing this condition
Imaging guidelines and diagnostic protocols are clearly explained to enable readers to select the appropriate work-up when hydrocephalus is suspected

Table of Contents

Prologue
Part I. Basic Sciences:
1. Anatomy and physiology of the cerebrospinal fluid system Thomas A. Kosztowski, Aristotelis Filippidis, Rory Goodwin, Benjamin Elder and Daniele Rigamonti
2. Neuropathology of human hydrocephalus Marc R. Del Bigio
3. Animal models of hydrocephalus Marianne Juhler
4. Genetics of hydrocephalus Jun Zhang
5. The epidemiology of hydrocephalus Are Brean and Per Kristian Eide
Part II. Pathophysiology:
6. Pathophysiology of gait dysfunction in normal pressure hydrocephalus Jonathan Pindrik, Amy Bastian and Daniele Rigamonti
7. The pathophysiologic basis of cognitive dysfunction in idiopathic normal pressure hydrocephalus Norman Relkin and Heather Katzen
8. Incontinence and lower urinary tract symptoms in normal pressure hydrocephalus Adam P. Klausner and Samuel P. Robinson
9. Normal pressure hydrocephalus grading scales Masatsune Ishikawa
Part III. Diagnosis:
10. The differential diagnosis of normal pressure hydrocephalus Marianne Juhler, Daniele Rigamonti and Carsten Wikkelso
11. Core imaging in adult hydrocephalus Benjamin D. Elder, Patrick Bankah, Ari M. Blitz, Rory C. Goodwin, Thomas A. Kosztowski, Ignacio Jusué-Torres and Daniele Rigamonti
12. Imaging of the cerebrospinal fluid circulation Olivier Balédent
13. Cerebrospinal fluid dynamics and infusion techniques Cemil Kayis and Gunes A. Aygok
14. Monitoring of intracranial pressure and assessment of cerebrospinal fluid dynamics Marek Czosnyka, Martin U. Schuhmann, Stefano Signoretti, Zofia Czosnyka and John D. Pickard
15. Cerebrospinal fluid biomarkers in idiopathic normal pressure hydrocephalus Andrew A. Tarnaris
Part IV. Treatment and Outcomes:
16. Hydrocephalus shunt procedures Benjamin D. Elder and Daniele Rigamonti
17. Hydrocephalus shunts: principles, hardware, shunt testing Zofia Czosnyka, Krzysztof Cieslicki, John D. Pickard and Marek Czosnyka
18. Management of shunts in normal pressure hydrocephalus: follow-up and late complications Ahmed Mohyeldin, Ammar Shaikhouni and John McGregor
19. Endoscopic third ventriculostomy: indications, technique, outcome, and complications Steffen Fleck, Jörg Baldauf and Henry W. S. Schroeder
20. Outcome of idiopathic normal pressure hydrocephalus Gunes A. Aygok
Part V. Associated Conditions:
21. Normal pressure hydrocephalus syndrome secondary to hemorrhage, infection and malignancy Rory C. Goodwin and Daniele Rigamonti
22. Low-pressure syndromes and cerebrospinal fluid leaks: diagnosis and management Debraj Mukherjee and Wouter I. Schievink
23. Management of the adult with congenital hydrocephalus Jonathan Pindrik and Edward S. Ahn
24. Management of hydrocephalus with associated cerebrospinal fluid pathologies Petra Margarete Klinge
25. Chiari malformation and hydrocephalus in adults Aristotelis S. Filippidis and Harold L. Rekate
26. Pseudotumor cerebri syndrome John D. Pickard and Nicholas Higgins
Epilogue
Index