Vascular malformations of the brain and spine pose many management challenges. This text provides a comprehensive, state-of-the-art review of the natural history, treatment options, and outcomes of patients with these conditions. Despite their relative rarity, these lesions are responsible for devastating injury to individuals and can cause an enduring physical, psychological, and economic burden on patients and families. Many new therapeutic options are now available with the advent of novel surgical, endovascular, and radiosurgical techniques. The basic sciences have fuelled development of small molecule and biologic therapies targeting the molecular basis of disease. Authored by international experts in the fields of neurosurgery, neurology, radiology, and radiation oncology, this book provides state-of-the-art treatment plans and discussions of ideal therapy. This text is aimed at practitioners in the fields of neurology, neurosurgery, neuroradiology, radiation oncology, rehabilitation medicine and allied fields who care for patients with brain and spinal vascular malformations.
Includes comprehensive treatment plans and discussions (surgery, endovascular and radiation treatment options) for arteriovenous malformations of the brain and spine
Written by a group of international experts in fields of neurosurgery, radiology, and radiation oncology
Richly illustrated with diagnostic images and illustrations of key procedures - a key learning tool for practitioners at all career stages
CONTENTS
Preface

Part I. Development, Anatomy, and Physiology of Arteriovenous Malformations of the Central Nervous System:
1. Development of the central nervous system vasculature and the pathogenesis of brain arteriovenous malformations
2. Cranial vascular anatomy and implications for arteriovenous malformation and dural arteriovenous fistula treatment
3. Spinal vascular anatomy and implications for treatment of arteriovenous malformations
4. Physiology and hemodynamics of arteriovenous malformations
5. Natural history of arteriovenous malformations and indications for treatment

Part II. Evaluation and Treatment Considerations for Arteriovenous Malformations:
6. Imaging evaluation of arteriovenous malformations
7. Intraoperative evaluation of blood flow with indocyanine green videoangiography
8. Neuromonitoring for arteriovenous malformation surgery
9. Neuroanesthesia for treatment of arteriovenous malformations
10. Classification of brain and spinal arteriovenous malformations and arteriovenous fistulas

Part III. Surgical Approaches to the Treatment of Arteriovenous Malformations:
11. Surgical approaches and nuances for supratentorial arteriovenous malformations
12. Surgical approaches and nuances for arteriovenous malformations in the posterior fossa
13. Surgical management of cerebral dural arteriovenous fistulas
14. Surgery of spinal arteriovenous malformations and arteriovenous fistulas
15. Surgery of basal ganglia, thalamic, and brainstem arteriovenous malformations

Part IV. Medical, Endovascular, and Radiosurgical Treatment of Arteriovenous Malformations:
16. Complications of arteriovenous malformation rupture and medical management of hemorrhage
17. Endovascular treatment of supratentorial arteriovenous malformations
18. Endovascular treatment of arteriovenous malformations of the posterior fossa
19. Endovascular treatment of arteriovenous fistulas of the brain
20. Endovascular management of vein of Galen malformations
21. Endovascular treatment of spinal arteriovenous malformations and arteriovenous fistulas
22. Radiosurgical basics for the treatment of arteriovenous malformations: indications and techniques
23. Radiosurgery for brain arteriovenous malformations and arteriovenous fistulas
24. Radiosurgery for spinal arteriovenous malformations and arteriovenous fistulas
25. Multidisciplinary treatment of arteriovenous malformations
26. Palliative treatment of inoperable arteriovenous malformations
27. Pediatric arteriovenous malformations: special considerations
28. Management of residual or recurrent arteriovenous malformations

Index.