This book provides a comprehensive, up-to-date review of the pathology of the neoplastic and non-neoplastic diseases that occur in the mediastinum. The pathologic and relevant clinical features are discussed, and detailed diagnostic criteria for various diseases are given, along with information about the most relevant laboratory tests. The features of thymomas, thymic carcinomas, neuroendocrine carcinomas and germ cell tumors are discussed in detail, including the utilization of immunostains and other ancillary tests in diagnosing these diseases. An algorithmic approach to the differential diagnosis of mediastinal lymphomas is given, and a novel clinico-pathologic classification helps readers diagnose and treat thymomas. Cardiac lesions, mesothelioma and other intrathoracic lesions are also reviewed. The book features more than 650 images, and downloadable copies of these are included on a CD-ROM, packaged with the print book. Pathology of the Mediastinum will be of interest to practising surgical pathologists, thoracic surgeons, oncologists and radiologists.
Written by leading authorities in the field with a wealth of experience in diagnosing and managing the diseases discussed
Highly illustrated with over 650 images, which are also included as downloadable copies on a CD-ROM
An algorithmic approach to the differential diagnosis of mediastinal lymphomas provides a quick reference for readers
Contents
Preface
1. The mediastinum Alberto M. Marchevsky and Mark R. Wick
2. Imaging of the mediastinum Xiaoqin Wang and Ajay Singh
3. Inflammatory diseases of the mediastinum Alberto M. Marchevsky and Mark R. Wick
4. The thymus gland Alberto M. Marchevsky and Mark R. Wick
5. Pathology of non-neoplastic conditions of the thymus Alberto M. Marchevsky and Mark R. Wick
6. Low-grade and intermediate-grade malignant epithelial tumors of the thymus: thymomas Alberto M. Marchevsky, Saul Suster and Mark Wick
7. High-grade malignant epithelial tumors of the thymus: primary thymic carcinomas Mark R. Wick, Alberto M. Marchevsky and Saul Suster
8. Neuroendocrine tumors of the thymus Alberto M. Marchevsky, Saul Suster and Mark R. Wick
9. Germ cell tumors of the mediastinum Sean R. Williamson and Thomas M. Ulbright
10. Parathyroid lesions, paragangliomas, thyroid tumors, and pleomorphic adenomas of the mediastinum Mark R. Wick and Alberto M. Marchevsky
11. Hematopoietic neoplasms of the mediastinum Serhan Alkan
12. Cystic lesions of the mediastinum Alberto M. Marchevsky and Mark R. Wick
13. Mesenchymal tumors of the mediastinum Bonnie Balzer, Mark R. Wick and Susan Parson
14. Tell me what you need, so I'll know what to say Frank C. Detterbeck
15. Clinical pathology of disorders of the mediastinum Kent Lewandrowski
16. Surgical pathology of the heart Gregory A. Fishbein, Atsuko Seki and Michael C. Fishbein
17. Morphologic alterations of serous membranes of the mediastinum in reactive and neoplastic settings Aliya N. Husain and Thomas Krausz
Index.