Covers the many ways light can be used to treat diseases not only physical diseases but also mental and psychological diseases
Presents the history and fundamentals of photomedicine for nonspecialists
Explains how light can cause and exacerbate existing diseases
Addresses cutting-edge applications in stem cell biology, nanotechnology, advanced drug delivery, and cell signaling networks
Summary
Providing the most comprehensive, up-to-date coverage of this exciting biomedical field, Handbook of Photomedicine gathers together a large team of international experts to give you a complete account of the application of light in healthcare and medical science. The book progresses logically from the history and fundamentals of photomedicine to diverse therapeutic applications of light, known collectively as phototherapies. It facilitates your understanding of human diseases caused by light, the rationale for photoprotection, and major applications of phototherapy in clinical practice.
The handbook begins with a series of historical vignettes of pioneers from the last two centuries. It also presents the fundamentals of physics and biology as applied to photomedicine. It next examines conditions and diseases caused by light, including skin cancer, dermatoses, and immunosuppression.
The remainder of the book focuses on the most important clinical therapeutic applications of different kinds of light that vary in both wavelength and intensity. The book discusses ultraviolet phototherapy for skin diseases and infections and presents the basic science of photodynamic therapy and its use in cancer therapy and other medical specialties. It then covers mechanistic studies and clinical applications of low-level laser (light) therapy as well as the use of high power or surgical laser therapy in specialties, such as dentistry and dermatology. The book concludes with a collection of miscellaneous types of phototherapy.

History and Fundamentals
Introduction: Historical Vignettes from the Field of Photomedicine
Michael R. Hamblin and Ying-Ying Huang
History and Fundamentals of Lasers and Light Sources in Photomedicine
Edward Victor Ross and Lee Miller
Light-Tissue Interactions
Pradeep K. Gupta, Mahesh K. Swami, and Harishankar Patel
History and Fundamentals of Photodynamic Therapy (PDT)
Tyler G. St. Denis and Michael R. Hamblin
History and Fundamentals of Low-Level Light Therapy (LLLT)
Asheesh Gupta and Michael R. Hamblin
Diseases Caused by Light
Ultraviolet (UV) Effects on Skin
Kris Nys and Patrizia Agostinis
Photocarcinogenesis Nonmelanoma Skin Cancer
Gary M. Halliday, Scott N. Byrne, J. Guy Lyons, and Diona L. Damian
Autoimmune Photodermatoses
John L.M. Hawk
Photoaggravated Dermatoses
PierGiacomo Calzavara-Pinton and Raffaella Sala
Photoaging
Rui Yin and Michael R. Hamblin
UV Radiation (UVR)-Induced Immunosuppression
Mary Norval and Prue H. Hart
The Porphyrias
Eric Gou and Karl E. Anderson
Photoprotection
Chanisada Wongpraparut and Henry W. Lim
Botanical Antioxidants for Photochemoprevention
Eiman Mukhtar, Vaqar Adhami, and Hasan Mukhtar
Reversal of DNA Damage in the Skin with DNA Repair Liposomes
Peter Wolf
Climate Change and UVR Exposure
Mohammad Ilyas
Photochemistry and Photobiology of Vitamin D
Michael F. Holick
Ultraviolet Phototherapy
UVB Phototherapy for Psoriasis
Edidiong Ntuen Kaminska, Piergiacomo Calzavara-Pinton, and Bernhard Ortel
PUVA Therapy
Juliana Basko-Plluska, Herbert Hönigsmann, and Bernhard Ortel
Extracorporeal Photopheresis
Fiona Dignan and Julia Scarisbrick
UVC Therapy for Infections
Tianhong Dai and Michael R. Hamblin
Photodynamic Therapy
Recent Advances in Developing Improved Agents for PDT
Penny Joshi, Courtney Saenz, Joseph R. Missert, and Ravindra K. Pandey
5-Aminolevulinic Acid and Its Derivatives
Asta Juzeniene and Patrycja Mikolajewska
Gentically Encoded Photosensitizers: Structure, Photosensitization Mechanisms, and Potential Application to Photodynamic Therapy
Cristina Flors and Santi Nonell
Light Dosimetry for PDT: Basic Concepts
Henricus J.C.M. Sterenborg, Robert L.P. van Veen, Jan-Bonne Aans, Arjen Amelink, and Dominic J. Robinson
Multimodality Dosimetry
Jarod Finlay
Cell Death and PDT-Based Photooxidative (Phox)-Stress
Abhishek D. Garg and Patrizia Agostinis
Vascular and Cellular Targeted PDT
Shannon M. Gallagher-Colombo and Theresa M. Busch
PDT for Increased Delivery of Anticancer Drugs
Elodie Debefve, Yabo Wang, Thorsten Krueger, and Hubert van den Bergh
Targeting Strategies in Photodynamic Therapy for Cancer Treatment
Marlène Pernot, Céline Frochot, Régis Vanderesse, and Muriel Barberi-Heyob
Enhancing PDT of Cancer with Mechanism-Based Combination Strategies
Lei Zak Zheng, R. Bryan Sears, Iqbal Massodi, Stanley Kimani, and Tayyaba Hasan
Nanoparticles for PDT
Girgis Obaid and David A. Russell
Drug Delivery Systems for PDT
Ryan F. Donnelly
Antimicrobial PDT for Clinical Infectious Diseases
Anja Eichner, Fernanda Pereira Gonzales, and Tim Maisch
PDT and the Immune System
Fatma Vatansever and Michael R. Hamblin
Detection of Bladder Cancer by Fluorescence Cystoscopy: From Bench to Bedside the Hexvix Story
Georges Wagnières, Patrice Jichlinski, Norbert Lange, Pavel Kucera, and Hubert van den Bergh
Photochemical Internalization: From Bench to Bedside with a Novel Technology for Targeted Macromolecule Therapy
Kristian Berg, Anette Weyergang, Anders H gset, and P l K. Selbo
The Story of TOOKAD: From Bench to Bedside
Avigdor Scherz and Yoram Salomon
PDT in Ophthalmology
Patrycja Nowak-Sliwinska, Andrea Weiss, Michel Sickenberg, and Hubert van den Bergh
PDT in Dermatology
Alexis Sidoroff
PDT in the Gastrointestinal Tract
Drew Schembre
Photodynamic Applications in Brain Tumors
Sam Eljamel
PDT for Malignant Pleural Disease
Charles B. Simone, Melissa Culligan, Joseph S. Friedberg, and Keith A. Cengel
Clinical PDT in the Chinese Region
Yih-Chih Hsu and Zheng Huang
PDT and Fluorescent Diagnostics in the Russian Federation
Elena G. Vakulovskaya
Low-Level Light Therapy
Chromophores (Photoacceptors) for LLLT
Tiina I. Karu
LLLT Signaling Pathways
Da Xing and Shengnan Wu
Irradiation Parameters, Dose Response, and Devices
James D Carroll
LLLT: Clearly a New Paradigm in the Management of Cancer Therapy-Induced Mucositis
Rene-Jean Bensadoun
LLLT for Wound Healing
Lilach Gavish
LLLT in the Treatment of Pain
Roberta Chow
LLLT in Arthritis and Tendinopathies
Jan Magnus Bjordal and Rodrigo A.B. Lopes-Martins
LLLT and Light-Emitting Diode Therapy on Muscle Tissue: Performance, Fatigue, and Repair
Cleber Ferraresi and Nivaldo A. Parizotto
LLLT for Stroke and Brain Disease
Takahiro Ando, Ying-Ying Huang, and Michael R Hamblin
LLLT for Nerve and Spinal Cord Regeneration
Nivaldo A. Parizotto
LLLT in Dentistry
Daiane Thais Meneguzzo and Leila Soares Ferreira
LLLT and Stem Cells
Heidi Abrahamse
LLLT for Cosmetics and Dermatology
Pinar Avci, Theodore Nyame, and Michael R. Hamblin
Surgical Laser Therapy
Lasers and Intense Pulsed Light Treatment of Skin
Rui Yin, Garuna Kositratna, and Rox R Anderson
Therapeutic Uses of Lasers in Eye Care
Charles Wormington
Lasers Used in Dentistry
Kirpa Johar and Vida de Arce
Lasers in Urology
Naeem Bhojani and James Lingeman
Lasers in Otolaryngology
James A. Burns and Anca M. Barbu
Laser Targeting to Nanoparticles for Theranostic Applications
James Ramos, Huang-Chiao Huang, and Kaushal Rege
Laser Immunotherapy
Tomas Hode, Xiaosong Li, Mark Naylor, Lars Hode, Peter Jenkins, Gabriela Ferrel, Robert E. Nordquist, Orn Adalsteinsson, John Lunn, Michael R. Hamblin, Luciano Alleruzzo, and Wei R. Chen
Tissue Repair by Photochemical Cross-Llinking
Irene E. Kochevar and Robert W. Redmond
Other Phototherapy and Future Outlook
Optical Guidance for Cancer Interventions
Brian C. Wilson and Robert Weersink
Phototherapy for Newborn Jaundice
Michael Andrew Choma
Biological Evidence of the Efficacy of Light Therapy in Psychiatric Disorders
Anne-Marie Gagné and Marc Hebert
Future Developments in Photomedicine and Photodynamic Therapy
Thierry J. Patrice