Examines diagnosis, monitoring of therapeutic intervention, and future directions of physiologic imaging of brain tumors
Author taps into extensive expertise found in the Johns Hopkins School of Medicine, as well as at other centers such as the University of California at San Francisco, Duke University, and Memorial Sloan-Kettering Cancer Center
This book presents a comprehensive overview of current state-of-the-art clinical physiological imaging of brain tumors. It focuses on the clinical applications of various modalities as they relate to brain tumor imaging, including techniques such as blood oxygen level dependent functional magnetic resonance imaging, diffusion tensor imaging, magnetic source imaging/magnetoencephalography, magnetic resonance perfusion imaging, magnetic resonance spectroscopic imaging, amide proton transfer imaging, high angular resolution diffusion imaging, sodium imaging, and molecular imaging. Featuring contributions from renowned experts in functional imaging, this book examines the diagnosis and characterization of brain tumors, details the application of functional imaging to treatment planning and monitoring of therapeutic intervention, and explores future directions in physiologic brain tumor imaging. Intended for neuro-oncologists, neurosurgeons, neuroradiologists, residents, and medical students, Functional Brain Tumor Imaging is a unique resource that serves to advance patient care and research in this rapidly developing field.

TABLE OF CONTENTS
Section I: Diagnosis and Characterization of Brain Tumors.- MR perfusion imaging ASL, T2* DSC and T1 DCE methods.- Diffusion Tensor Imaging.- Molecular imaging.- Role of PET in Neuro-Oncology.- MR Spectroscopic Imaging.- Section II: Physiologic Imaging for Planning and Monitoring of Therapeutic Intervention.- BOLD fMRI for Pre-surgical Planning.- BOLD fMRI for Pre-surgical Planning.- DTI for Pre-surgical Planning.- MSI/MEG for Pre-surgical Planning.- Role of BOLD and DTI in Radiation Therapy Planning.- BOLD and DTI Assessment of Brain Plasticity.- MR Perfusion Imaging for Monitoring Treatment Response.- MR Spectroscopic Imaging Role in Assessing Tumor Progression vs. Treatment Effects.- PET Role in Assessing Tumor Progression vs. Treatment Effects.- Role of MRSI and PET in Assessing Therapeutic Response.- Section III: Future Directions in Physiologic Brain Tumor Imaging.- Role of Novel MR Perfusion Sequences in Brain Tumor Imaging VASO, iVASO, APT.- Evolving Role of BOLD Imaging in Monitoring Therapeutic Intervention.- Advanced Diffusion Imaging HARDI, DSI, New Approaches to Fiber Tracking.- Ultra-High Field Diffusion Imaging.- Ultra-High Field MRSI.- Ultra-High Field Non-Proton Magnetic Resonance Imaging, including Sodium Imaging.- Future Clinical Applications of Molecular Imaging Nanoparticles, Cellular Probes, Imaging of Gene Expression.- Future Role of MSI/MEG in Brain Tumor Research