The book is split into four parts 1) definition, classification and a list of uremic toxins, 2) application of MS for uremic toxin research, 3) description of selected uremic toxins such as chemical structure, metabolism, analytical methods, serum levels, toxicity and clinical implication, and removal methods, and 4) therapeutic removal of uremic toxins by hemodialysis, peritoneal dialysis and oral sorbent.

SECTION 1: UREMIC TOXINS

Chapter 1. Uremic Toxins: An Integrated Overview of Definition and Classification
Richard J. Glassock and Shaul G. Massry

Chapter 2. Classification and a List of Uremic Toxins
Nathalie Neirynck, Rita De Smet, Eva Schepers, Raymond Vanholder, and Griet Glorieux

Chapter 3. Analysis of Uremic Toxins with Mass Spectrometry
Toshimitsu Niwa

SECTION 2: SELECTED UREMIC TOXINS

Chapter 4. Indoxyl Sulfate
Toshimitsu Niwa

Chapter 5. p-Cresyl Sulfate
Anneleen Pletinck, Raymond Vanholder, and Griet Glorieux

Chapter 6. 3-Carboxy-4-methyl-5-propyl-2-furanpropionic Acid
Toshimitsu Niwa

Chapter 7. Phenylacetic Acid
Anna Schulz and Joachim Jankowski

Chapter 8. Homocysteine and Hydrogen Sulfide: Two Opposing Aspects in the Pathobiology of Sulfur Compounds in Chronic Renal Failure
Alessandra F. Perna and Diego Ingrosso

Chapter 9. Guanidino Compounds
Sunny Eloot, Griet Glorieux, Peter Paul De Deyn, and Raymond Vanholder

Chapter 10. Asymmetric Dimethylarginine
Vladimír Teplan and Jaroslav Racek

Chapter 11. Nicotinamide Metabolites
Przemyslaw Rutkowski and Boleslaw Rutkowski

Chapter 12. Dicarbonyls (Glyoxal, Methylglyoxal, and 3-Deoxyglucosone)
Naila Rabbani and Paul J Thornalley

Chapter 13. Glucose Degradation Products in Peritoneal Dialysis
Monika Pischetsrieder and Sabrina Gensberger

Chapter 14. Dinucleoside Polyphosphates
Joachim Jankowski and Vera Jankowski

Chapter 15. Parathyroid Hormone
Shaul G. Massry and Miroslaw Smogorzewski

Chapter 16. 2-Microglobulin
Suguru Yamamoto, Junichiro James Kazama, Hiroki Maruyama, Ichiei Narita, and Fumitake Gejyo

Chapter 17. Cytokines
Björn Anderstam, Bengt Lindholm, and Peter Stenvinkel

Chapter 18. Free Immunoglobulin Light Chains
Gerald Cohen and Walter H. Hörl

Chapter 19. Advanced Glycation End-Products (AGEs)
Naila Rabbani and Paul J Thornalley

Chapter 20. Oxidized Albumin
Maurizio Bruschi, Giovanni Candiano, Laura Santucci, and Gian Marco Ghiggeri

SECTION 3: THERAPEUTIC REMOVAL OF UREMIC TOXINS

Chapter 21. Therapeutic Removal of Uremic Toxins by Hemodialysis
Tammy L. Sirich, Pavel Aronov, and Timothy W. Meyer

Chapter 22. Therapeutic Removal of Uremic Toxins by Peritoneal Dialysis
Malgorzata Debowska, Elvia García-López, Jacek Waniewski, and Bengt Lindholm

Chapter 23. Therapeutic Removal of Uremic Toxins by Oral Sorbent
Toshimitsu Niwa

Index