Contents Chapter 1: Pharmacology: The Chemical Control of Physiology Chapter 2: Drug Affinity and Efficacy Chapter 3: Predicting Agonist Effect Chapter 4: Drug Antagonism: Orthosteric Drug Effects Chapter 5: Allosteric Drug Effects Chapter 6: Enzymes as Drug Targets Chapter 7: Pharmacokinetics I: Permeation and Metabolism Chapter 8: Pharmacokinetics II: Distribution and Multiple Dosing Chapter 9: In Vivo Pharmacology Chapter 10: Safety Pharmacology Chapter 11: Answers to Chapter Questions Chapter 12: Derivations and Proofs