INTRODUCTION TO IMMUNOLOGY
Introduction
Immune responses
Infection and immunity
Immunopathology and immunotherapy
Thinking about immunology
THE IMMUNE SYSTEM
Introduction
Host defence against infection
The anatomical basis of immunity
The cellular basis of immunity
The molecular basis of immunity
Immune responses and disease
Learning outcomes
INFECTION AND IMMUNITY
Introduction
Pathogens and infectious disease
Host defence against infection
Infection and immunity in action
Immunity and vaccines
Learning outcomes
Questions and answers
FUNCTIONAL ANATOMY OF THE IMMUNE SYSTEM
Introduction
Natural barriers
Functional anatomy of innate immunity
Functional anatomy of adaptive immunity
Development of blood cells and organs of immunity
Stem cell and gene therapy
Learning outcomes
Questions and answers
Further Study Questions
INNATE IMMUNITY
Introduction
Induction of innate immunity
"Tissue-resident cells" of innate immunity
Recruited effectors of innate immunity
Haematopoiesis and myeloid cells
Vaccines and adjuvants
Learning outcomes
Questions and answers
Further Study Questions
T CELL-MEDIATED IMMUNITY
Introduction
The Major Histocompatibility Complex (MHC)
Antigen presentation
The anatomical basis of T cell responses
T lymphocyte activation
Effector and memory functions of T cells in infection
T cell development & selection
Adoptive cell therapy
Learning outcomes
Questions and answers
Further study questions
ANTIBODY-MEDIATED IMMUNITY
Introduction
Antibody structure and function
B cell responses
B cell memory, antibodies, and long-term resistance to re-infection
B cell differentiation and selection
Therapeutic antibodies
Learning outcomes
Questions and answers
Further study questions
IMMUNITY, DISEASE AND THERAPY
Introduction
What are the mechanisms of tissue damage caused by the immune system?
Why do we make harmful immune responses to harmless? antigens?
Immunopathology and therapy in action
Transplantation immunology
Tumour immunity
Conclusions
Learning outcomes
Questions and answers