Introduction - Kaufmann/Kabelitz

The immune response to infectious agents


I. General Methods

Radbruch A - Phenotyping and isolation of functionally distinct leukocyte populations; Schütze S - Magnetic isolation of subcellular compartments; Berzofsky J - Prediction of MHC ligands and T-cell epitopes; McMichael A - Quantitative analysis of T-cell responses; Schurr E - Genetics of susceptibility and resistance to infection; Wiker H - Proteomic approaches to study immunity in infection; Sioud M - siRNA as a tool to study immune responses in infection; Schröder JM - Isolation and characterization of antimicrobial peptides; Karin M - Toll - and NOD-like receptors in anti-infective immunity; von Andrian UH - Visualization of immune responses in vivo


II. Murine Models


A. In vitro analysis



Czuprynski CJ - Isolation of lymphocytes from infected animals; Busch DH - Killer cell assays; Kiyono H - Quantification of murine T-cell cytokine responses; Gordon S - Isolation and functional charactzerization of macrophages

B. In vivo analysis


Ehlers S - Measuring immune responses in vivo; Belkaid Y - Control of infection by regulatory T-cells; Stockinger B - Th17 cells in inflammation

C. Specific Models


Orme IM - Murine models of tuberculosis; Muller I - The leishmaniasis model; Autenrieth IB - Murine models of infection with extracellular bacteria; Flynn JL - Local immune responses in the lung; Romani L - Murine models of fungal infections; Powrie F - Immunity in the gut; Reddehase MJ - Murine cytomegalovirus infection; Lingnau K/von Gabain A - Boosting of immune responses by adjuvants


III. Human System

Banchereau J - Subpopulations of human dendritic cells; Yssel H - Measuring human cytokine responses; Seitzer U - Measuring immune responses in situ; Garcia JV - Humanized mice for the analysis of human immune responses

IV. Appendix

Benoist C - The NIH knock-out mouse project; Beutler B - Forward genetic analysis to understand innate immunity