Table of contents Treatment of pediatric bone sarcomas.- Molecular biology of pediatric bone sarcomas.- Surgical options for limb salvage in immature patients with extremity sarcoma.- Location of sarcomas within the bone. The growth plate.- Location of malignant bone tumors.- Historical histologic study about the barrier effect of the physis against metaphyseal osteosarcoma.- Growth plate involvement in malignant bone tumors: Relationship between imaging methods and histological findings.- Imaging-based indications for resection with epiphyseal preservation.- Removal of metaphyseal malignant bone tumors in children with preservation of the epiphysis. Epiphysiolysis before excision.- Clinical results. - Control of disease Histological study of margins.- Other techniques for epiphyseal preservation (intraepiphyseal osteotomy).- Advantages of epiphysiolysis before excision.- Questions and answers.