Manual of Pathology of the Human Placenta, Second Edition is a concise, practical manual of placental pathology. While references are made to the more encyclopedic Pathology of the Human Placenta, this Manual is designed as a user-friendly, easy-to-read bench manual that can be used in the grossing room as well as at the microscope. Features of the text include: - A section on the approach to the placental specimen, providing suggestions on what to do, as well as when and how to do it. - Discussion of detailed development and normal histology of all parts of the placenta for those wanting to learn about specific areas of the placenta. - Discussion of placental lesions, disease processes related to the placenta, neoplasms, and trophoblastic lesions. - An overview of the legal implications of placental examination and future directions. - "Suggestions for Examination and Report" includes key points in gross examination, sectioning, and diagnosis. Suggestions for comments in the surgical pathology report guide the reader in problematic situations or when the diagnosis or diagnostic implications are unclear. - An abundance of tables summarize pertinent information and provide easy access to the differential diagnoses of various lesions. The descriptive text is enhanced by 345 color illustrations. Manual of Pathology of the Human Placenta, Second Edition is a must-have reference for every pathologist, resident and pathology assistant.

Foreword by Kurt Benirschke.............................................................. vii
Preface to the First Edition................................................................... ix
Preface to the Second Edition.............................................................. xi
Section I Approach to the Specimen
1 Evaluation of the First-Trimester Products
of Conception................................................................................. 3
2 Evaluation of the Second-Trimester
Products of Conception................................................................. 13
3 Macroscopic Evaluation of the Second- and
Third-Trimester Placenta.............................................................. 23
4 Microscopic Evaluation of the Second- and
Third-Trimester Placenta.............................................................. 43
Section II Development and Normal Histology
5 Early Placental Development....................................................... 59
6 Chorionic Villi: Histology
and Villous Development............................................................. 69
7 Overview and Microscopic Survey of the Placenta.................. 85
8 Extravillous Trophoblast, Trophoblastic Invasion,
and Fibrinoid.................................................................................. 109
Section III Multiple Gestation
9 Multiple Gestation: General Aspects.......................................... 121
10 Multiple Gestation: Twin Variants
and Related Conditions................................................................ 141
Contents
xiv Preface to the Second Edition
Section IV Abnormalities of the Placenta
11 Abortion and the Placenta in Chromosomal Anomalies......... 165
12 Postpartum Hemorrhage, Subinvolution
of the Placental Site, and Placenta Accreta................................ 185
13 Placental Shape Aberrations......................................................... 203
14 Pathology of the Fetal Membranes............................................. 219
15 Pathology of the Umbilical Cord................................................. 247
Section V Disease Processes and the Placenta
16 Infectious Diseases......................................................................... 281
17 Maternal Diseases Complicating Pregnancy............................. 321
18 Placental Malperfusion................................................................. 335
19 Miscellaneous Placental Lesions.................................................. 355
20 Placental Abnormalities in Fetal Conditions............................. 379
21 Fetal Thrombotic Vasculopathy................................................... 401
Section VI Neoplasms and Gestational Trophoblast Disease
22 Neoplasms....................................................................................... 415
23 Hydatidiform Moles...................................................................... 427
24 Choriocarcinoma............................................................................ 447
25 Lesions of Extravillous Trophoblast............................................ 459
Section VII Legal Considerations and New Directions
26 Legal Considerations..................................................................... 475
27 New Directions: What is New in Placental Studies?................ 487
Appendix A............................................................................................. 495
Appendix B............................................................................................. 499
Index........................................................................................................ 525