Contents:
Experimental intracerebral hemorrhage iron, hemoglobin and free radicals
Hua, Y., Keep, R. F., Hoff, J. T., Xi, G.:
Deferoxamine therapy for intracerebral hemorrhage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
Clark, J. F., Loftspring, M., Wurster, W. L., Beiler, S., Beiler, C., Wagner, K. R., Pyne-Geithman, G. J.:
Bilirubin oxidation products, oxidative stress, and intracerebral hemorrhage . . . . . . . . . . . . . . . . . . . . . . . . 7
Song, S., Hua, Y., Keep, R. F., He, Y., Wang, J., Wu, J., Xi, G.:
Deferoxamine reduces brain swelling in a rat model of hippocampal intracerebral hemorrhage . . . . . . . . . . . 13
Rojas, H., Lekic, T., Chen, W., Jadhav, V., Titova, E., Martin, R. D., Tang, J., Zhang, J.:
The antioxidant effects of melatonin after intracerebral hemorrhage in rats . . . . . . . . . . . . . . . . . . . . . . . . . 19
Bao, X., Wu, G., Hu, S., Huang, F.:
Poly(ADP-ribose) polymerase activation and brain edema formation by hemoglobin
after intracerebral hemorrhage in rats . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23
He, Y., Hua, Y., Song, S., Liu, W., Keep, R. F., Xi, G.:
Induction of autophagy in rat hippocampus and cultured neurons by iron . . . . . . . . . . . . . . . . . . . . . . . . . . 29
Titova, E., Ostrowski, R. P., Rowe, J., Chen, W., Zhang, J. H., Tang, J.:
Effects of superoxide dismutase and catalase derivates on intracerebral hemorrhage-induced
brain injury in rats . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33
Yamashita, S., Okauchi, M., Hua, Y., Liu, W., Keep, R. F., Xi, G.:
Metallothionein and brain injury after intracerebral hemorrhage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37
Experimental intracerebral hemorrhage inflammation and thrombin
Sharp, F., Liu, D.-Z., Zhan, X., Ander, B. P.:
Intracerebral hemorrhage injury mechanisms: glutamate neurotoxicity, thrombin, and Src . . . . . . . . . . . . . . 43
Gong, Y., Xi, G., Hu, H., Gu, Y., Huang, F., Keep, R. F., Hua, Y.:
Increase of brain thrombin activity after experimental intracerebral hemorrhage. . . . . . . . . . . . . . . . . . . . . . 47
Gao, Z., Wang, J., Thiex, R., Rogove, A. D., Heppner, F. L., Tsirka, S. E.:
Microglial activation and intracerebral hemorrhage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51
O'Lynnger, T., He, Y., Hu, H., Hua, Y., Muraszko, K. M., Xi, G.:
Concomitant intracerebral infusion of tissue plasminogen activator and thrombin leads to brain injury . . . . . . 55
Wu, J., Yang, S., Xi, G., Song, S., Fu, G., Keep, R. F., Hua, Y.:
Microglial activation and brain injury after intracerebral hemorrhage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59
Gong, Y., Xi, G., Wan, S., Gu, Y., Keep, R. F., Hua, Y.:
Effects of aging on complement activation and neutrophil infiltration after intracerebral hemorrhage . . . . . . . 67
Experimental intracerebral hemorrhage other mechanisms
Keep, R. F., Xiang, J., Ennis, S. R., Andjelkovic, A., Hua, Y., Xi, G., Hoff, J. T.:
Blood brain barrier function in intracerebral hemorrhage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73
Chopp, M., Li, Y.:
Treatment of stroke and intracerebral hemorrhage with cellular and pharmacological
restorative therapies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79
Titova, E., Kevil, C. G., Ostrowski, R. P., Rojas, H., Liu, S., Zhang, J. H., Tang, J.:
Deficiency of CD18 gene reduces brain edema in experimental intracerebral hemorrhage in mice . . . . . . . . . 85
Grossetete, M., Rosenberg, G. A.:
Tissue inhibitor of matrix metalloproteinase-3 (TIMP-3) lacks involvement in bacterial
collagenase-induced intracerebral hemorrhage in mouse . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89
Nakamura, T., Kuroda, Y., Okabe, N., Shibuya, S., Kawai, N., Tamiya, T., Xi, G., Keep, R. F., Itano, T., Nagao, S.:
Radial glia marker expression following experimental intracerebral hemorrhage . . . . . . . . . . . . . . . . . . . . . 95
Hartman, R. E., Rojas, H. A., Lekic, T., Ayer, R., Lee, S., Jadhav, V., Titova, E., Tang, J., Zhang, J. H.:
Long-term effects of melatonin after intracerebral hemorrhage in rats . . . . . . . . . . . . . . . . . . . . . . . . . . . . 99
Rohde, V., Uzma, N., Thiex, R., Samadani, U.:
Management of delayed edema formation after fibrinolytic therapy for intracerebral hematomas:
preliminary experimental data . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101
Li, Y., Ogle, M. E., Wallace IV, G. C., Lu, Z.-Y., Yu, S. P., Wei, L.:
Erythropoietin attenuates intracerebral hemorrhage by diminishing matrix metalloproteinases
and maintaining blood brain barrier integrity in mice . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105
Qin, Z., Xi, G., Keep, R. F., Silbergleit, R., He, Y., Hua, Y.:
Hyperbaric oxygen for experimental intracerebral hemorrhage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 113
Titova, E., Ostrowski, R. P., Zhang, J. H., Tang, J.:
Effect of amantadine sulphate on intracerebral hemorrhage-induced brain injury in rats . . . . . . . . . . . . . . . 119
Experimental intracerebral hemorrhage model development and characterization
Hartman, R. E., Rojas, H., Tang, J., Zhang, J.:
Long-term behavioral characterization of a rat model of intracerebral hemorrhage . . . . . . . . . . . . . . . . . . 125
Kuroiwa, T., Okauchi, M., Hua, Y., Schallert, T., Keep, R. F., Xi, G.:
Neurological deficits and brain edema after intracerebral hemorrhage in Mongolian gerbils . . . . . . . . . . . . 127
VIII Contents
Lekic, T., Tang, J., Zhang, J. H.:
Rat model of intracerebellar hemorrhage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 131
Lekic, T., Tang, J., Zhang, J. H.:
A rat model of pontine hemorrhage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 135
Human intracerebral hemorrhage
Wang, Y. F., Wu, J. S., Mao, Y., Chen, X. C., Zhou, L. F., Zhang, Y.:
The optimal time-window for surgical treatment of spontaneous intracerebral hemorrhage:
result of prospective randomized controlled trial of 500 cases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141
Morgan, T., Zuccarello, M., Narayan, R., Keyl, P., Lane, K., Hanley, D.:
Preliminary findings of the minimally-invasive surgery plus rtPA for intracerebral hemorrhage
evacuation (MISTIE) clinical trial . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 147
Xia, C. Y., Zhang, R., Mao, Y., Zhou, L. F.:
Pediatric cerebrovascular diseases: report of 204 cases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153
Ding, H. Y., Han, X., Lv, C. Z., Dong, Q.:
Xenon-CT study of regional cerebral blood flow around hematoma in patients with basal
ganglia hemorrhage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 161
Qiu, T. M., Zhang, Y., Wu, J. S.:
Preliminary application of pyramidal tractography in evaluating prognosis of patients
with hypertensive intracerebral hemorrhage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 165
Experimental intracranial hemorrhage (non-intracerebral hemorrhage)
Rosell, A., Foerch, C., Murata, Y., Lo, E. H.:
Mechanisms and markers for hemorrhagic transformation after stroke. . . . . . . . . . . . . . . . . . . . . . . . . . . . 173
Ayer, R. E., Zhang, J. H.:
The clinical significance of acute brain injury in subarachnoid hemorrhage and opportunity
for intervention. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 179
Su, H., Hao, Q., Shen, F., Zhu, Y., Lee, C. Z., Young, W. L., Yang, G. Y.:
Development of a cerebral microvascular dysplasia model in rodents . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185
Hu, S. L., Hu, R., Li, F., Liu, Z., Xia, Y. Z., Cui, G. Y., Feng, H.:
Hyperbaric oxygen preconditioning protects against traumatic brain injury at high altitude . . . . . . . . . . . . . 191
Human intracranial hemorrhage (non-intracerebral hemorrhage)
Kim, H., Marchuk, D. A., Pawlikowska, L., Chen, Y., Su, H., Yang, G. Y., Young, W. L.:
Genetic considerations relevant to intracranial hemorrhage and brain arteriovenous malformations . . . . . . . . 199
Pearl, J. D., Macdonald, R. L.:
Vasospasm after aneurysmal subarachnoid hemorrhage: need for further study . . . . . . . . . . . . . . . . . . . . . 207
Kawai, N., Nakamura, T., Tamiya, T., Nagao, S.:
Regional cerebral blood flow and oxygen metabolism in aneurysmal subarachnoid hemorrhage:
positron emission tomography evaluation of clipping versus coiling