The Third Edition of Molecular Biology: Genes to Proteins is a comprehensive guide through
the basic molecular processes and genetic phenomena of both prokaryotic and eukaryotic cells.
Designed for undergraduate and fi rst year graduate students, this multi-purpose text has been
completely updated to include many important advances made in the fi eld of molecular biology.
Maintaining the original structure-function approach evident in the fi rst two editions of David
Freifelder's classic text, this book provides students with an accessible overview of molecular
biology before moving into more in-depth discussions. Broken into six sections, topics are
strategically arranged to cover basic information that is necessary in understanding the more
advanced topics focused on in later sections.
SECTION STRUCTURE
Section 1 and 2: Protein Structure and Function and Nucleic Acids and Nucleoproteins provide
the information required to understand the chemical basis of molecular biology.
Section 3: Genetics and Virology provides information required to understand the biological basis
of molecular biology.
Section 4: DNA Metabolism explores DNA replication, repair, and recombination in bacteria,
eukaryotes and archaeons.
Section 5: RNA Synthesis and Processing examines mechanisms that bacteria, eukaryotes,
and archaeons use to synthesize RNA, regulate RNA syntheses, and process transcripts to form
mature RNA molecules.
Section 6: Protein Synthesis describes the structure and function of the bacterial protein
synthetic machinery in bacteria, eukaryotes and archaeons.Table of Contents
Preface
Chapter 1: Introduction to Molecular Biology
Chapter 2: Protein Structure
Chapter 3: Protein Structure
Chapter 4: Deoxyribonucleic Acid Structure
Chapter 5: Nucleic Acid Technology
Chapter 6: Chromosome Structure
Chapter 7: Genetic Analysis in Molecular Biology
Chapter 8: Viruses in Molecular Biology
Chapter 9: DNA Replication
Chapter 10: DNA Damage and Repair
Chapter 11: Recombination
Chapter 12: Transposons and Other Mobile Elements Found in Genomes
Chapter 13: Bacterial RNA Polymerase
Chapter 14: Regulation of Bacterial Gene Transcription
Chapter 15: RNA Polymerase II: Basal Transcription
Chapter 16: RNA Polymerase II: Regulation
Chapter 17: RNA Polymerase II: Cotranscriptional and Posttranscriptional
Processes
Chapter 18: Ribosomal RNA, Transfer RNA, and Organellar RNA Synthesis
Chapter 19: Protein Synthesis: The Genetic Code
Chapter 20: Protein Synthesis: The Ribosome