Latest comprehensive knowledge in molecular mechanism of pancreatic disease
Detailed description of diagnosis and treatment
Abundantly illustrated with approx. 300 color illustrations

This book is based on the latest comprehensive data about molecular mechanism of acute pancreatitis, chronic pancreatitis and pancreatic cancer. The diagnostic techniques including histology, radiology, sonography etc. are based on the sensitivity and specificity of the respective methods. Special focus is given to the indication and contraindication to surgical techniques.

The book contains specific treatment modality and results for the first time after long-term outcome evaluation. Surgical techniques are displayed with colored sketches series.

Table of contents

Section 1 - Anatomy of the Pancreas

Chapter 1-Development of the Pancreasand Response to Disease - D. E. Bockman
Chapter 2-Congenital Anomalies of the Pancreas and the Extrahepatic Bile Ducts - H. Fujii, Y. Matsumoto, K. Sudo
Chapter 3-Surgical Vascular Anatomy and Histology - Y. Mikami, A. Otsuka, M. Unno

Section 2 - Physiology and Pathophysiology of the Pancreatic Functions

Chapter 4-Pancreatic Exocrine Secretion - P. Layer, J. Keller
Chapter 5-Physiology and Pathophysiology of Endocrine Pancreatic Secretion - B. Gallwitz, U. R. Fölsch
Chapter 6-Sphincter of Oddi Physiology and Pathophysiology - M. Staritz

Section 3 - Clinical Standards of Diagnostic Measures

Chapter 7-Ultrasound -S. Tanaka
Chapter 8-Contrast-Enhanced CT and MRI -H.-J. Brambs
Chapter 9-Endoscopic Retrograde Cholangiopancreatography - H. Saisho
Chapter 10-Fine-Needle Aspiration Biopsy of the Pancreas - K. Yamao, H. N. Mizuno, K. Takahashi, Y. Shimizu, T.Koshikawa
Chapter 11-FDG-PET and PET/CT in Pancreatic Cancer - S. N. Reske
Chapter 12-Laboratory Diagnosis of Exocrine and Endocrine Dysfunctions in Inflammatory and Neoplastic Lesions - K. Schütte , S. Kahl, P. Malfertheiner
Chapter 13-Guidelines, Clinical Evaluation, Short Track - J. Mössner

Section 4 - Acute Pancreatitis

Chapter 14-Etiology and Epidemiology of Acute Pancreatitis - P. G. Lankisch, P. Maisonneuve, A. B. Lowenfels
Chapter 15-Epidemiology and Intervention During the Clinical Course of Biliary Acute Pancreatitis - R. C. Carter, C. W. Imrie Chapter 16- Pathogenesis and Pathophysiology of Acute Pancreatitis - M. L. Steer, G. Perides
Chapter 17-Natural Course of Acute Pancreatitis - H. G. Beger, B. M. Rau
Chapter 18-Classification of Severe Acute Pancreatitis - R. Isenmann
Chapter 19.1-Biochemical Diagnosis, Staging, and Prediction - B. M. Rau
Chapter 19.2-Imaging Diagnosis of Acute Pancreatitis - E. J. Balthazar
Chapter 20-Nonsurgical Management of Acute Pancreatitis - P. A. Banks, K. J. Mortele
Chapter 21.1-Indications for the Surgical Management of Necrotizing Pancreatitis - H. G. Beger, B. M. Rau
Chapter 21.2-Debridement and Closed Packing for the Treatment of Necrotizing Pancreatitis - M. Reinblatt, C. Fernandez-del-Castillo, A. L. Warshaw
Chapter 21.3-Necrosectomy and Redressing - P. Götzinger
Chapter 21.4-Necrosectomy and Closed Lavage - B. M. Rau, H. G. Beger
Chapter 21.5-Infected Necrosis Minimally Invasive Necrosectomy - R. Carter, A. P. Wysocki
Chapter 21.6-Benefits and Limitations of Necrosectomy - O. Mann, T. Strate, E. Yekebas, J. Izbicki
Chapter 22-Surgical Management of Pancreatic Abscess - R. Bittner, B. M. Rau, H. G. Beger
Chapter 23-Surgical Management of Pseudocysts after Acute Pancreatitis - B. M. Rau, H. G. Beger
Chapter 24-Interventional Management of Pancreatic Fluid Collections and Abscesses - T. H. Baron
Chapter 25-Pancreatic and Intestinal Fistulas - G. Tsiotos, J. Tsiaoussis
Chapter 26-Late Outcome after Necrosectomy - I. H. Nordback, J. Sand

Section 5 - Chronic Pancreatitis

Chapter 27-Mechanisms of Pain in Chronic Pancreatitis - P. Di Sebastiano, F. F. Di Mola
Chapter 28-Natural Course of Chronic Pancreatitis - J. Enrique Domínguez-Muñoz
Chapter 29-Chronic Pancreatitis: Inflammatory Mass in the Head of the Pancreas Pacemaker of Chronic Pancreatitis - H. G. Beger, F. Gansauge, M. Schwarz, B. Poch
Chapter 30-Diagnosis: Functional Testing, Radiological Work-up of Chronic Pancreatitis - M. Kahl, J. Keller, P. Layer
Chapter 31-Medical Management of Chronic Pancreatitis - P. G. Lankisch, H. Lübbers, R. Mahlke
Chapter 32-Tropical Chronic Pancreatitis - H. Ramesh
Chapter 33-Hereditary Chronic Pancreatitis: Diagnosis and Management - N. Teich, V. Keim
Chapter 34-Endoscopic Interventional Treatment - R. Jakobs, J. F. Riemann
Chapter 35-Indication for Surgical Treatment in Chronic Pancreatitis - H. G. Beger, B. Poch
Chapter 36-Pancreatic Duct Drainage Procedures - R. A. Prinz, M. Gaffud, M. Edwards
Chapter 37-Duodenum-Preserving Pancreatic Head Resection - H. G. Beger, B. M. Rau, B. Poch
Chapter 38-Pancreaticoduodenctomy for Chronic Pancreatitis With or Without Pylorus Preservation - L. W. Traverso
Chapter 39-Central Pancreatectomy - C. Iacono, L. Bortolasi, G. Serio
Chapter 40-Distal Pancreatectomy in Patients with Chronic Pancreatitis - J. Lunger, K. Mair, M. Junger, M. H. Schoenberg
Chapter 41-Total Pancreatectomy - I. Ihse
Chapter 42-Surgical Treatment of Pseudocysts in Chronic Pancreatitis - R. Grützmann, H. D. Saeger
Chapter 43-Late Outcome After Medical and Surgical Treatment of Chronic Pancreatitis - L. Gullo, R. Pezzilli

Section 6 - Pancreatic Cancer

Chapter 44-Epidemiology of Pancreatic Cancer - A. B. Lowenfels, P. Maisonneuve
Chapter 45-Pathology of Pancreatic Cancer - R. H. Hruban, A. Maitra, N. Fukushima
Chapter 46-Genetic Pathways in Pancreatic Tumorigenesis - E. Gallmeier, S. E. Kern
Chapter 47-The Clinical Assessment of Pancreatic Cancer - E. J. Shin, M. I. Canto
Chapter 48-The Staging of Pancreatic Cancer - J. R. Rodríguez, C. Fernandez-del Castillo
Chapter 49-Oncological Management of Pancreatic Cancer in Advanced Stages - D. Laheru
Chapter 50-Indications for Resection of Pancreatic Cancer - O. J. Hines, H. A. Reber
Chapter 51-The Kausch-Whipple Pancreatectomy - C. R. Ferrone, M. F. Brennan
Chapter 52-Pylorus-Preserving Pancreaticoduodenectomy - R. D. Schulick, J. L. Cameron
Chapter 53-Management of Tumor Invasion/Adhesion to the Superior Mesenteric-Portal Vein During Pancreatectomy -
F. Mosca, U. Boggi, M. Del Chiaro
Chapter 54-Margin Status Following Pancreaticoduodenectomy for Pancreatic Adenocarcinoma: Implications of R Status -
C. P. Raut, G. Varadhachary, H. Wang, E. P. Tamm, J. B. Fleming, D. B. Evans
Chapter 55-Subtotal Left Resection for Pancreatic Cancer - A. Nakeeb, B. Safar
Chapter 56-Total Pancreatectomy for Pancreatic Cancer - J. Y. Tracey, M. Bouvet, A. R. Moossa
Chapter 57-Laparoscopic Management of Pancreatic Neoplasms - C. G. S. Hüscher, C. Ponzano, M. Di Paola
Chapter 58-Bypass Procedures in the Treatment of Nonresectable Carcinoma of the Head of the Pancreas - M. G. House, K. D. Lillemoe
Chapter 59-Resected Pancreatic Cancer - G. R. Varadhachary, J. L. Abbruzzese
Chapter 60-Management of Locally Advanced and Recurrent Pancreas Cancer - A. Jimeno, M. Hidalgo
Chapter 61-Survival After Medical and Surgical Treatment of Pancreatic Adenocarcinoma - J. F. Tseng, C. Fernandez-del Castillo, A. L. Warshaw

Section 7 - Endocrine Tumors of the Pancreas

Chapter 62 -Pancreatic Endocrine Tumors: Epidemiology, Pathology, Pathophysiology, and Diagnosis - C. Shibata, Y. Funayama, I. Sasaki
Chapter 63-Surgical Treatment of Insulinomas - M. Sunamura, S. Fukuyama
Chapter 64-Surgical Treatment of the Gastrinoma - M. Imamura, I. Komoto
Chapter 65-Surgical Treatment of Rare Endocrine Tumors - S. Egawa, M. Sunamura, S. Matsuno, M. Unno
Chapter 66-Outcome after Surgical Treatment of Endocrine Pancreatic Tumors - S. Fukuyama, S. Matsuno, S. Egawa, M. Sunamura

Section 8 - Periampullary Tumors

Chapter 67-Histopathology of Tumors of the Papilla of Vater - W. Kimura
Chapter 68-Clinical Diagnosis of Adenoma of the Papilla of Vater - K. Shiratori
Chapter 69-Clinical Diagnosis of Periampullary Carcinoma - T. Kamisawa, A. Okamoto
Chapter 70-Endoscopic Management of Adenoma - H. Maguchi, M. Osanai, A. Katanuma, K. Takahashi
Chapter 71-Surgical Management of Adenoma - S. Ikeda, Y. Yasunami
Chapter 72-Surgical Treatment of Carcinoma of the Ampulla of Vater - K. Yamaguchi, M. Tanaka
Chapter 73-Surgical Resection of Distal Common Bile Duct Carcinoma - T. Rikiyama, M. Unno, S. Matsuno
Chapter 74-Cancer of the Duodenum Surgical Treatment - T. Imaizumi, M. Ishii, K. Tobita, S. Douwaki, H. Makuuchi
Chapter 75-Long-Term Outcome After Resection of Periampullary Carcinoma - H. Amano, T. Takada

Section 9 - Cystic Neoplasia of the Pancreas

Chapter 76-Cystic Neoplasms of the Pancreas Pathological Aspects - T. Furukawa
Chapter 77-Clinical Diagnosis and Staging - M. Tanaka
Chapter 78-Surgical Treatment of Cystic Tumors of the Pancreas - T. Mori, N. Abe, M. Sugiyama, Y. Atomi

Section 10 - Congenital Anomalies of the Pancreas

Chapter 79-Congenital Cysts: Diagnosis, Clinical Impact, and Management - G. Klöppel, H. D. Saeger
Chapter 80-Pancreas Divisum Diagnosis and Endoscopic Management - N. Soehendra, T. L. Ang, Y. Zhong, S. Seewald
Chapter 81-Surgical Treatment of Pancreas Divisum - H. G. Beger, P. Poch
Chapter 82-Biliopancreatic Maljunction: Classification, Diagnosis, and Treatment - T. Onogawa, T. Rikiyama, M. Unno, S. Matsuno

Section 11 - Pancreatic Injury

Chapter 83-Pancreatic Trauma: Diagnosis, Treatment, Complications, and Late Outcome - J. M. Mayer, P. Tuncyurek

Section 12 - Transplantation of the Pancreas

Chapter 84-Islet Transplantation and Results - C. Ricordi, A. Pileggi
Chapter 85-Pancreas Transplantation - U. T. Hopt