Statistics are complicated, but to a large extent this is a reflection of the way in which they are taught. In this book, Dr Bahkai takes a back-to-basics approach to explaining statistics specifically for a medically literate audience. Based on the successful Practical Issues in Clinical Trial Design series published in Remedica's flagship journal Clinical Researcher, and supplemented by key contributions from other leading international experts, each article provides essential background information to each topic, explores its meaning, and explains how and when it should be applied. Readers will gain not only an understanding of the basics of medical statistics, but also critical insight into how to review and evaluate clinical trial evidence.

Readership:
Medical students, statistics students, clinical researchers, pharmaceutical sales representatives.

Content:
The place of observational studies and randomized controlled trials; Interpreting P values; Confidence intervals; The number needed to treat; Relative risk ratios and odds ratios; Understanding survival analyses in randomized controlled trials; Choosing the right sample size for a randomized controlled trial; Methods of randomization in clinical trials; Practical issues in trial design: methods of blinding or masking in clinical trials; Understanding equivalence trials; Design and evaluation of bioequivalence studies; Power calculations in non-inferiority trials; Interim monitoring in clinical trials; Crossover trials in clinical research; Meta-analysis in clinical research; Intention-to-treat analysis; Subgroup analysis in clinical trials; Unique aspects of multicenter trials; Understanding endpoints in clinical trials; Identifying and controlling for confounding factors in clinical trials; Principles of health economic analyses; Insights for evaluating a clinical trial.