Thoroughly updated for its Second Edition, this volume is the most comprehensive, current reference on perioperative transfusion medicine and coagulation. It provides complete information on all current blood products and transfusion risks, transfusion and coagulation issues during the preoperative, intraoperative, and postoperative periods, and specific concerns in each surgical subspecialty. Eighteen new chapters in this edition cover blood shortages, economic concerns, emergency needs, virus transmission, parasitic and septic risks, immunosuppression risks, non-infectious risks, production and storage issues, hemoglobin-based oxygen-carrying solutions, perfluorocarbon-based oxygen-carrying solutions, preoperative plateletphoresis, volume resuscitation, antifibrinolytics, aprotinin, DDAVP, platelet inhibitors, burn patients, and post-surgical stress response.
FEATURES:


Details what you need to know about the storage and administration of blood

Focuses on indications for transfusion, methods to avoid, pharmacologic adjustments, and technical equipment usage

Dr. Spiess is well known in the field and in the surgical setting

Contributors are from a broad base of specialties: (anesthesiologists, surgeons, blood banking specialists)

Includes current infectious disease concerns (AIDS)

Differentiates the needs of different patient types

NEW TO THIS EDITION:

Many new chapters including blood shortages, economics, virus transmission, parasitic and septic risks, emergency needs, immunosuppression risks, non-infectious risks, production and storage issues

Contents


1. A History of Transfusion
2. The Contemporary Economics of Transfusion
3. Blood Supplies Now and in the Future
4. Ethics of Transfusion
5. Legal Aspects of Transfusion

The Physiologic Basis for Blood Management: A New Look
6. A Physiologic Basis for the Transfusion Trigger
7. The Physiology of Anemia in Acute and Chronic Illness
8. The Physiology of Hemostasis: Protein Reactions and Control
9. Platelet Physiology: Cellular and Protein Interactions
10. Physiology of Erythropoiesis to include iron Ken Bridges and David Henry
11. New Concepts of Oxygen Transport as They Apply to Transfusion Medicine Respiratory Function of Hemoglobin

Transfusion Risks
12. Infectious Risks of Transfusion: Michael Busch.
13. Immunomodulation by Transfusion
14. Transfusion Reactions/ Other Adverse Events of Transfusion

Blood Component Therapy
15. Understanding the Transfusion Service
16. Allogeneic Blood Therapy
17. Storage Lesions
18. Coagulation Therapy Products
19. Platelets: A Primer
20. Quality Control and Hospital Blood Utilization Oversight

Alternatives to Allogeneic Blood
21. Pre-Operative Autologous Donation
22. Erythropoetin Therapy
23. Hemoglobin Based Oxygen Carriers
24. Perfluorocarbon Emulsions

Trauma and the Bleeding Patient
25. Initial Resuscitation of the Hemorrhaging Patient
26. Transfusion and Coagulation Therapy in Trauma and Burns
27. Massive Transfusion

Coagulation Issues
28. Coagulation Products to be Utilized in the Perioperative Period
29. Coagulation Monitoring for Surgery
30. Anticoagulant Therapy Implications for Surgery
31. Management of Patients with Congenital Clotting Deficiencies who need Surgery:
32. Perioperative Management of the Hypercoagulable Patient:
33. Pharmacologic Approaches to Decrease Bleeding
34. Fibrin Glue/Platelet Gels

Anesthesia Considerations
35. Monitoring of Oxygen Supply and Consumption
36. Anesthesia Techniques in Blood Conservation
37. Perioperative Red Cell Salvage and Autotransfusion
38. Intraoperative Acute Normovolemic Hemodilution
39. Platelet Rich Plasma Utilization/ Platelet Salvage
40. Hypothermia and Hemorrhage

Transfusion and Surgical Subspecialties
41. Surgery in Patients with Red Cell Disorders
42. Surgery in the Patient Who Refuses Transfusion/Bloodless Surgery
43. Coagulation Transfusion and Cardiac Surgery
44. Major Vascular Surgery
45. Solid Organ Transplantation, Blood Usage and Coagulation Problems
46. Orthopedic Surgery Blood Usages

Transfusion Issues In Other Specialities
47. Obstetrics and Gynecology
48. Hemorrhage in Pediatrics
49. Transfusion and Coagulation Dysfunction in Neurosurgery
50. Transfusion in Oncology Pat Ford and David Henry

Post-Operative Transfusion Issues
51. Outcomes and Transfusion
52. The Transfusion Decision
53. Undertransfusion Is it a Legitimate Concern?
54. Overall Strategies of Blood Conservation