This new book brings together leading research from around the globe. Leukemia is cancer that begins in blood cells. In people with leukemia, the bone marrow produces abnormal white blood cells. The abnormal cells are leukemia cells. At first, leukemia cells function almost normally. In time, they may crowd out normal white blood cells, red blood cells, and platelets.
The scope of the book includes the four common types of leukemia: Chronic lymphocytic leukemia (chronic lymphoblastic leukemia, CLL) most often affecting people over age 55. Chronic myeloid leukemia (chronic myelogenous leukemia, CML) affects mainly adults. Acute lymphocytic leukemia (acute lymphoblastic leukemia, ALL) the most common type of leukemia in young children. Acute myeloid leukemia (acute myelogenous leukemia, AML) which occurs in both adults and children. New advances in diagnosis, pathogenesis and therapy are presented.


Chapter 1 - Chronic Myelogenous Leukemia (pp. 1-26)
Authors / Editors: Müller, Ludmila and Pawelec, Graham (University of Tübingen Medical School, Germany)

Chapter 2 - The Immune Response to Chronic Myeloid Leukaemia (pp. 27-59)
Authors / Editors: Clark, Richard E. (Royal Liverpool University Hospital, Liverpool)

Chapter 3 - Pathogenesis of Testicular Acute Lymphoblastic Leukaemia (pp. 61-81)
Authors / Editors: El Morsi, Hisham and Jewell, Andrew (Kingston University, Surrey) Yong, Kwee Lan and Patterson, Keith (University College London, London)

Chapter 4 - Acute Tumor Lysis Syndrome Induced by Corticosteroids (pp. 83-94)
Authors / Editors: Duzova, Ali (Hacettepe University Faculty of Medicine, Ankara, TURKEY)

Chapter 5 - Paraffin Section Immunotyping of Leukaemias (pp. 95-111)
Authors / Editors: Juneja, S. (Royal Melbourne Hospital, Melbourne, Australia) Westerman, D. and Seymour, J. F. (Peter MacCallum Cancer Center, Melbourne, Australia)

Chapter 6 - Cellular Immunotherapy of Leukemia (pp. 113-138)
Authors / Editors: Yasukawa, Masaki (Ehime University School of Medicine, Ehime, Japan)

Chapter 7 - Therapeutic Activity of Cladribine in Patients with B-cell Chronic Lymphocytic Leukemia (pp. 139-161)
Authors / Editors: Robak, Tadeusz (Medical University of Lodz, Poland)

Chapter 8 - Biology, Natural History and Clinical Features of TEL/AML 1-Positive Childhood Leukaemias (pp. 163-184)
Authors / Editors: Zuna, Jan (Medical School Charles University Prague, Czech Republic)