Widely considered the premier text in pediatric infectious diseases, Feigin and Cherry's Textbook of Pediatric Infectious Diseases, 9th Edition: 2-Volume Set, provides authoritative, up-to-date coverage of this rapidly changing field. Extensively revised by Drs. James Cherry, Sheldon L. Kaplan, Gail J. Demmler-Harrison, William J. Steinbach, Peter J. Hotez, and new editor John V. Williams, this two-volume reference delivers the information you need on epidemiology, public health, preventive medicine, clinical manifestations, diagnosis, treatment, and much more. It serves as a reliable, everyday resource for practicing ID specialists, and an invaluable reference for medical students, residents, and fellows in ID, pediatricians and internists, and others who work with neonates, children, and adolescents or in public health.

Discusses infectious diseases according to organ systems that may be affected, as well as individually by microorganisms, placing emphasis on clinical manifestations that may be related to the organism causing the disease.
Provides detailed information regarding the best means to establish a diagnosis, explicit recommendations for therapy, and the most appropriate uses of diagnostic imaging.
Includes expanded information on Q fever, antibiotic resistance and antibiotic agents, human coronaviruses, pox viruses, and infections in the compromised host, and contains new COVID-19 content across numerous chapters.
Features a new chapter on antimicrobial stewardship, and new coverage of antivirals for pox viruses.
Reflects today's more aggressive infectious and antibiotic-resistant organisms as well as emerging and re-emerging infectious diseases.
Contains hundreds of full-color images (many are new!), including clinical photos, radiographic images, drawings, charts, and graphs.
Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices. Additional digital ancillary content may publish up to 6 weeks following the publication date.
Author Information
Edited by James Cherry, MD, Distinguished Professor of Pediatrics, David Geffen School of Medicine at UCLA; Attending Physician, Pediatric Infectious Diseases, Mattel Children's Hospital UCLA, Los Angeles, CA; Sheldon L. Kaplan, MD, Professor and Vice-Chairman for Clinical Affairs, Head, Section of Infectious Diseases, Department of Pediatrics, Baylor College of Medicine; Chief, Infectious Disease Service, Texas Children's Hospital, Houston, TX; Gail J. Demmler-Harrison, MD, Professor, Department of Pediatrics, Section of Infectious Diseases, Baylor College of Medicine; Attending Physician, Infectious Diseases Service, Texas Children's Hospital, Houston, TX; William Steinbach, MD, Associate Professor of Pediatrics, Molecular Genetics and Microbiology, Department of Pediatrics, Department of Molecular Genetics and Microbiology, Attending Physician, Division of Pediatric Infectious Diseases, Duke University Medical Center, Durham, North Carolina; Peter J Hotez, MD, PhD, FAAP, FASTMH and John V Williams, MD


Part 1 - Host-Parasite Relationships and the Pathogenesis of Infectious Diseases

1. Molecular Determinants of Microbial Pathogenesis
2. Normal and Impaired Immunologic Responses to Infection
3. The Host Response to Infections: The Omics Revolution
4. Fever: Pathogenesis and Treatment
5. The Human Microbiome
6. Epidemiology and Biostatistics of Infectious Diseases
Part 2 - Infection of Specific Organ Systems

Section 1 - Upper Respiratory Tract Infections

7. The Common Cold
8. Infections of the Oral Cavity
9. Pharyngitis (Pharyngitis, Tonsillitis, Tonsillopharyngitis, and Nasopharyngitis)
10. Uvulitis
11. Peritonsillar, Retropharyngeal, and Parapharyngeal Abscesses
12. Cervical Lymphadenitis
13. Parotitis
14. Rhinosinusitis
15. Otitis Externa
16. Otitis Media
17. Mastoiditis
18. Croup (Laryngitis, Laryngotracheitis, Spasmodic Croup, Laryngotracheobronchitis, Bacterial Tracheitis, and Laryngotracheobronchopneumonitis) and Epiglottitis (Supraglottitis)
Section 2 - Lower Respiratory Tract Infections

19. Acute Bronchitis
20. Chronic Bronchitis
21. Bronchiolitis and Infectious Asthma
22. Pediatric Community-Acquired Pneumonia
23. Empyema and Lung Absess
24. Children's Interstitial Lung Disease and Hypersensitivity Pneumonitis
25. Cystic Fibrosis
Section 3 - Infections of the Heart

26. Infective Endocarditis
27. Infectious Pericarditis
28. Myocarditis
29. Acute Rheumatic Fever
30. Mediastinitis
Section 4 - Central Nervous System Infections

31. Bacterial Meningitis Beyond the Neonatal Period
32. Parameningeal Infections.
33. Fungal Meningitis
34. Eosinophilic Meningitis
35. Aseptic Meningitis and Viral Meningitis
36. Encephalitis and Meningoencephalitis
37. Parainfectious and Postinfectious Disorders of the Nervous System
37a. Parainfectious and Postinfectious Demyelinating Disorders of the Central Nervous System
37b. Infection-Associated Myelitis and Myelopathies of the Spinal Cord
37c. Guillain-Barreì Syndrome
Section 5 - Genitourinary Tract Infections

38. Urethritis
39. Cystitis and Pyelonephritis
40. Renal Abscess
41. Prostatitis
42. Genital Infections
Section 6 - Gastrointestinal Tract Infections

43. Esophagitis
44. Approach to Patients with Gastrointestinal Tract Infections and Food Poisoning
45. Clostridium Difficile Infection
46. Whipple Disease
Section 7 - Liver Diseases

47. Hepatitis
48. Cholangitis and Cholecystitis
49. Pyogenic Liver Abscess
50. Reye Syndrome
Section 8 - Other Intra-Abdominal Infections

51. Appendicitis and Pelvic Abscess
52. Pancreatitis
53. Peritonitis and Intra-Abdominal Abscess
54. Retroperitoneal Infections
Section 9 - Musculoskeletal Infections

55. Osteomyelitis
56. Septic Arthritis
57. Bacterial Myositis and Pyomyositis
Section 10 - Skin Infections

58. Cutaneous Manifestatiions of Systemic Infections
59. Roseola Infantum (Exanthem Subitum)
60. Skin Infections
60a. Bacterial Skin Infections
60b. Viral and Fungal Skin Infections
Section 11 - Ocular Infectious Diseases

61. Ocular Infections
Section 12 - Systemic Infectious Diseases

62. Bacteremia and Septic Shock
63. Fever Without Source and Fever of Unknown Origin
64. Toxic Shock Syndrome
65. Pediatric Acute Respiratory Distress Syndrome
Section 13 - Infections of the Fetus and Newborn

66. Approach to Infections in the Fetus and Newborn
Section 14 - Infections of the Compromised Host

67. Primary Immunodeficiency Diseases
68. The Febrile Neutropenic Patient
69. Opportunistic Infections in Hematopoietic Stem Cell Transplantation
70. Infections in Pediatric Heart Transplantation
71. Infections in Pediatric Lung Transplantation
72. Opportunistic Infections in Liver and Intestinal Transplantation
73. Opportunistic Infections in Kidney Transplantation
74. Infections Related to Prosthetic or Artificial Devices
75. Infections Related to Craniofacial Surgical Procedures
76. Infections in Burn Patients
Section 15 - Unclassified Infectious Diseases

77. Kawasaki Disease
78. Chronic Fatigue Syndrome
Part 3 - Infections with Specific Microorganisms

Section 16 - Bacterial Infections

79. Nomenclature for Aerobic and Anaerobic Bacteria
Subsection 1 - Gram-Positive Cocci

80. Staphylococcus aureus Infections (Coagulase-Positive Staphylococci)
81. Coagulase-Negative Staphylococcal Infections
82. Group A, Group C, and Group G Beta Hemolytic Streptococcal Infections
83. Group B Streptococcal Infections
84. Enterococcal and Viridans Streptococcal Infections
85. Pneumococcal Infections
86. Miscellaneous Gram-Positive Cocci
Subsection 2 - Gram-Negative Cocci

87. Moraxella catarrhalis
88. Meningococcal Disease
89. Gonococcal Infections
Subsection 3 - Gram-Positive Bacilli

90. Diphtheria
91. Anthrax
92. Bacillus Cereus and Other Bacillus Species
93. Arcanobacterium haemolyticum
94. Erysipelothrix rhusiopathiae
95. Listeriosis
96. Tuberculosis
97. Other Mycobacteria
98. Leprosy and Buruli Ulcer: The Major Cutaneous Mycobacterioses
99. Nocardia
100. Corynebacterium and Rhodococcus
Subsection 4 - Gram-Negative Bacilli

101. Citrobacter
102. Enterobacter
103. Extraintestinal Pathogenic Escherichia coli
104. Diarrhea-Causing and Dysentery-Causing Escherichia coli
105. Klebsiella
106. Morganella morganii
107. Proteus
108. Providencia
109. Shigella
110. Serratia
111. Salmonella
112. Plague (Yersinia pestis)
113. Other Yersinia Species.
114. Miscellaneous Enterobacteriaceae
115. Aeromonas
116. Pasteurella multocida
117. Cholera
118. Vibrio parahaemolyticus
119. Vibrio vulnificus
120. Miscellaneous Non-Enterobacteriaceae Fermentative Bacilli
121. Acinetobacter
122. Achromobacter (Alcaligenes)
123. Eikenella corrodens
124. Elizabethkingia and Chryseobacterium Species
125. Pseudomonas and Related Genera
126. Stenotrophomonas (Xanthomonas) maltophilia
Subsection 5 - Gram-Negative Coccobacilli

127. Aggregatibacter species
128. Brucellosis
129. Pertussis and Other Bordetella Infections
130. Klebsiella granulomatis
131. Campylobacter jejuni
132. Tularemia
133. Haemophilus influenzae
134. Other Haemophilus Species (Ducreyi, Haemolyticus, Influenzae Biogroup Aegyptius, Parahaemolyticus, and Parainfluenzae) and Aggregatibacter (Haemophilus) aphrophilus
135. Helicobacter pylori
136. Kingella kingae
137. Legionnaires' Disease, Pontiac Fever, and Related Illnesses
138. Streptobacillus moniliformis (Rat-Bite Fever)
139. Bartonella Infections
Subsection 6 - Treponemataceae

140. Lyme Disease
141. Relapsing Fever
142. Leptospirosis
143. Spirillum minus (Rat-Bite Fever)
144. Syphilis
145. Nonvenereal Treponematoses
Subsection 7 - Anaerobic Bacteria

146. Clostridial Intoxication and Infection
147. Infant Botulism
148. Tetanus
149. Actinomycosis
150. Bacteroides, Fusobacterium, Prevotella, and Porphyromonas
Section 17 - Viral Infections

151. Classification and Nomenclature of Viruses
Subsection 1 (DNA) - Parvoviridae

152. Human Parvovirus B19
153. Human Bocaviruses
Subsection 2 (DNA) - Polyomaviridae

154. Human Polyomaviruses
155. Human Papillomaviruses
Subsection 3 (DNA) - Adenoviridae

156. Adenoviruses
Subsection 4 (DNA) - Hepatoviridae

157. Hepatitis B and D Viruses
Subsection 5 (DNA) - Herpesviridae

158. Herpes Simplex Viruses 1 and 2
159. Cytomegalovirus
160. Epstein-Barr Virus
161. Human Herpesviruses 6A, 6B, 7, and 8
162. Varicella-Zoster Virus
Subsection 6 (DNA) - Poxviridae

163. Smallpox (Variola Virus)
164. Monkeypox and Other Poxviruses
165. Mimiviruses
Subsection 1 (RNA) - Picornaviridae

166. Enteroviruses, Parechoviruses, and Saffold Viruses
167. Rhinoviruses
168. Hepatitis A Virus
Subsection 2 (RNA) - Caliciviridae

169. Calicivirus (Norovirus, Sapovirus, Vesivirus, Lagovirus, Nebovirus)
170. Hepatitis E Virus
Subsection 3 (RNA) - Reoviridae

171. Reoviruses
172. Orbiviruses, Coltiviruses, and Seadornaviruses
173. Rotavirus
Subsection 4 (RNA) - Togaviridae

174. Rubella Virus
175. Alphaviruses
175a. Eastern Equine Encephalitis
175b. Western Equine Encephalitis
175c. Venezuelan Equine Encephalitis
175d. Chikungunya
175e. Ross River Virus Arthritis
175f. Other Alphaviral Infections
Subsection 5 - Flaviviridae

176. Flaviviruses
176a. St. Louis Encephalitis
176b. West Nile Virus
176c. Yellow Fever
176d. Dengue, Dengue Hemorrhagic Fever, and Severe Dengue
176e. Japanese Encephalitis
176f. Murray Valley Encephalitis
176g. Tick-Borne Encephalitis
176h. Zika Virus Infections
176i. Other Flaviral Infections
177. Hepatitis C Virus
Subsection 6 - Orthomyxoviridae

178. Influenza Viruses
Subsection 7 - Paramyxoviridae

179. Parainfluenza Viruses
180. Measles Virus
181. Mumps Virus
182. Respiratory Syncytial Virus
183. Human Metapneumovirus
Subsection 8 Rhabdoviridae

184. Rabies Virus
Subsection 9 - Arenaviridae and Filoviridae

185. Lymphocytic Choriomeningitis Virus
186. Arenaviral Hemorrhagic Fevers
187. Filoviral Hemorrhagic Fever: Marburg and Ebola Virus Fevers
Subsection 10 - Coronaviridae and Toroviridae

188. Human Coronaviruses, Including Middle East Respiratory Syndrome Coronavirus
Subsection 11 - Bunyaviridae

189. Hantaviruses.
190. La Crosse Encephalitis and Other California Serogroup Viruses
191. Other Bunyaviridae
191a. Rift Valley Fever
191b. Crimean-Congo Hemorrhagic Fever
191c. Phlebotomus Fever (Sandfly Fever)
191d. Oropouche Fever
191e. Toscana Virus
Subsection 12 - Retroviridae

192. Human Retroviruses
192a. Oncoviruses (Human T-Cell Lymphotropic Viruses) and Lentiviruses (Human Immunodeficiency Virus Type 2)
192b. Human Immunodeficiency Virus and Acquired Immunodeficiency Syndrome
Subsection 13 - Prion-Related Diseases

193. Transmissible Spongiform Encephalopathies (Creutzfeldt-Jakob Disease, Gerstmann-Sträussler-Scheinker Disease, Kuru, Fatal Familial Insomnia, New Variant Creutzfeldt-Jakob Disease, Sporadic Fatal Insomnia)
Section 18 - Chlamydia

194. Chlamydia Infections
Section 19 - Rickettsial Diseases

195. Rickettsial and Ehrlichial Diseases
Section 20 - Mycoplasma

196. Mycoplasma and Ureaplasma Infections
Section 21 - Fungal Diseases

197. Classification of Fungi
198. Aspergillosis
199. Blastomycosis
200. Candidiasis
201. Coccidioidomycosis
202. Paracoccidioidomycosis
203. Cryptococcosis
204. Histoplasmosis
205. Sporotrichosis
206. Mucormycosis and Entomopthoramycosis
207. Fusariosis and Scedosporiosis
208. Miscellaneous Mycoses
Section 22 - Parasitic Diseases

209. Classification and Nomenclature of Human Parasites
Subsection 1 - Protozoa

210. Amebiasis
211. Blastocystis hominis and Blastocystis spp. Infection
212. Entamoeba coli Infection
213. Giardiasis
214. Dientamoeba fragilis Infections
215. Trichomonas Infections
216. Balantidium coli Infection
217. Cryptosporidiosis
218. Cyclosporiasis, Cystoisosporiasis, and Microsporidiosis
219. Babesiosis
220. Malaria
221. Leishmaniasis
222. Trypanosomiasis
223. Naegleria, Acanthamoeba, and Balamuthia Infections
224. Toxoplasmosis
225. Pneumocystis Pneumonia
Subsection 2 - Nematodes

226. Parasitic Nematode Infections
Subsection 3 - Cestodes

227. Cestodes
Subsection 4 - Trematodes

228. Foodborne Trematodes
229. Schistosomiasis
Subsection 5 - Arthropods

230. Arthropods
Section 23 - Global Health

231. Global Health
232. International Travel Issues for Children
233. Infectious Disease Considerations in International Adoptees and Refugees
Part 4 - Therapeutics

234. Antibiotic Resistance
235. The Pharmacokinetic-Pharmacodynamic Interface: Determinants of Anti-Infective Drug Action and Efficacy in Pediatrics
236. Antibacterial Therapeutic Agents
237. Antimicrobial Prophylaxis
238. Outpatient Intravenous Antimicrobial Therapy for Serious Infections
239. Antiviral Agents
240. Antifungal Agents
241. Drugs for Parasitic Infections
242. Immunomodulating Agents
243. Probiotics
Part 5 - Prevention of Infectious Diseases

244. Health Care-Associated Infections
245. Active Immunizing Agents
246. Passive Immunization
Section 24 - Other Preventative Considerations

247. Public Health Aspects of Infectious Disease Control
248. Infections in Out-of-Home Child Care
249. Animal and Human Bites
250. Bioterrorism
Part 6 - Approach to the Laboratory Diagnosis of Infectious Diseases

251. Bacterial Laboratory Diagnosis
252. Fungal Laboratory Analysis: Specimen Collection, Direct Detection, and Culture
253. Viral Laboratory Diagnosis
254. Parasitic Laboratory Diagnosis