Discover a comprehensive and up-to-date reference resource for bone marrow pathology, complete with an extensive list of references

The diagnosis and treatment of bone marrow pathologies is one of the most critical areas of medical research and care. For years, Bone Marrow Pathology has served as the essential reference and teaching tool in the field of haematology, with an authoritative treatment of the subject written by acknowledged leaders in the field. Now fully updated to reflect urgent new changes to the theory and practice of haematology, it promises to serve a new generation of practitioners.


In the book, the characteristics and function of normal bone marrow are extensively discussed. Bone marrow pathology, including both aspirate films and trephine biopsy sections, is examined in a clinical context. The content is augmented by discussion of the peripheral blood findings and supplementary bone marrow tests. Readers of the sixth edition of Bone Marrow Pathology will also find:

Lavish illustrations with high-quality images of bone marrow and other associated images
Incorporation of new classifications including the WHO and International Consensus classifications, as well as new and expanded research areas
Emphasis on practical tools including differential diagnosis and common problems and pitfalls
A practical, integrated approach to diagnosis
Perfect for trainee and consultant haematologists and haematopathologists, Bone Marrow Pathology will also prove itself invaluable for cytogeneticists, molecular geneticists and anyone working in immunophenotyping.


About the Author

Barbara J. Bain is Professor of Diagnostic Haematology in the Centre for Haematology, Department of Immunology and Inflammation, Imperial College London, UK, and Honorary Consultant Haematologist, Imperial College NHS Trust, St Mary's Hospital, London.


David M. Clark is a Consultant Haematopathologist at the Haematological Malignancy Diagnostic Service, Nottingham University Hospitals NHS Trust and Honorary Clinical Senior Lecturer, Department of Medicine, Imperial College London.


Bridget S. Wilkins is a Consultant Haematopathologist at Guy's and St Thomas' Hospital NHS Foundation Trust, London and Hampshire Hospitals NHS Foundation Trust, Winchester, as well as Honorary Clinical Senior Lecturer, Department of Medicine, Imperial College London.


Vishakha Sovani is Consultant Haematopathologist at the Haematological Malignancy Diagnostic Service Nottingham, Nottingham University Hospitals NHS Trust.

Preface to the Sixth Edition

Acknowledgements

Abbreviations

1 The normal bone marrow: examining and reporting bone marrow specimens 1

2 Special techniques applicable to bone marrow diagnosis 63

3 Infection and reactive changes 115

4 Acute myeloid leukaemia mixed phenotype acute leukaemia the myelodysplastic neoplasms/syndromes and histiocytic and dendritic cell neoplasms 197

5 Myeloproliferative and myelodysplastic/myeloproliferative neoplasms and related conditions 276

6 Lymphoproliferative disorders 357

7 Plasma cell neoplasms and related conditions 507

8 Disorders of erythropoiesis granulopoiesis and thrombopoiesis 563

9 Miscellaneous disorders 613

10 Metastatic and non- haemopoietic tumours 675

11 Diseases of bone 716

Appendix 731

Index 742