Steroid Hormone Receptors in Endocrine Physiology and Diseases covers the role of steroid hormones in human physiology and receptor activity in the pathophysiology of disease. The book discusses how these receptors can be used as therapeutic targets for the treatment of conditions from cancer to aging, offering immediate applications of biochemical principles into clinical applications such as diagnosis and treatment. This book is a valuable reference for graduate and postdoctoral scientists but is also ideal for medical students interested in the functional role of various steroid hormone receptors in a wide variety of endocrine related diseases.Steroid hormone receptors (SHRs) are known to play vital roles in normal physiology through the control of development, differentiation, metabolic homeostasis and reproduction. Due to their involvement in various pathological and disease conditions, SHRs are also important therapeutic targets in several disorders including inflammation, autoimmune diseases, hormone-dependent cancers, osteoporosis and cardiovascular diseases.

Discusses the importance of steroid hormone receptors in the physiology and pathophysiology of various endocrine related diseases
Provides state-of-the-art information based on key research findings in the field, along with hypotheses and perspectives for future directions for basic and translational research and clinical applications
Offers a comprehensive description of the challenges associated with steroid hormone receptors-based therapies


1. A Historical Overview of Steroid Hormones and Their Receptors in Physiology and Pathology

2. Steroid Hormone Receptors in Endocrine Cancers

3. Steroid Hormone Receptors in Inflammation

4. Steroid Hormone Receptors in Hypertension and Cardiovascular Diseases

5. Steroid Hormone Receptors in Aging and Neurodegenerative Diseases

6. Steroid Hormone Receptors in Metabolic Disorders

7. Steroid Hormone Receptors in Autoimmune Diseases

8. Summary and Future Perspectives