Kuby Immunology is supported in Achieve, Macmillan's online learning system. Achieve is the culmination of years of development work put toward creating the most powerful online learning tool for biology students. It houses all of our renowned assessments, multimedia assets, e-books, and instructor resources in a powerful new platform.

Achieve supports educators and students throughout the full range of instruction, including assets suitable for pre-class preparation, in-class active learning, and post-class study and assessment.

Achieve content includes:

Achieve Online Homework Each Achieve chapter is accompanied by a digital homework assignment. Author-created end-of-chapter questions have been adapted into a variety of advanced question types, including cumulative questions. Scaffolded support of hints, answer-specific feedback, and stepped-out solutions provide a formative assessment experience.
In-Class and Remote Learning Activities In many classrooms, in-person and remote, student engagement is key to addressing misconceptions and reinforcing important concepts. The Kuby Immunology authors have provided instructions and materials for a variety of activities they use in their own classrooms to engage students. This digital update adds new concept map activities as well as instructions for adapting in-class activities for remote learning. These tried-and-true activities range in length and complexity and can serve as a springboard for active learning in the classroom.
Case Studies EC1 Kuby Immunology case studies explore immune function, disease, and treatment through the application of primary research and data. Students are led through a series of experiments and challenged to interpret the data and draw conclusions. By integrating experimental techniques from immunology, molecular biology, and biochemistry, these case studies teach students to think critically and synthesize their knowledge of immunology and other branches of science.
New Big Picture problems: With the importance of connecting concepts, and building on information, we've now added a brand new Big Picture question, easily identified, in each chapter.
Adaptive Quizzes: Adaptive Quizzes (formerly known as LearningCurve) now have more questions to ensure that students find the adaptive/extra questions useful in each chapter.
New In-Class Group Work activity: We've created a big picture concept map, for in-class group work, that is included within the Active Lecture Slides.
Active Lecture Slides include revised PowerPoint slide decks, with included iClicker questions in each chapter, so an instructor can easily include in class questions.


Kuby Immunology is now supported in Achieve, Macmillan's online learning system. Achieve is the culmination of years of development work put toward creating the most powerful online learning tool for biology students. It houses all of our renowned assessments, multimedia assets, e-books, and instructor resources in a powerful new platform.

Updates to the text

The new Chapter 17, Infectious Disease and Public Health, now includes discussions on patterns of infection, reservoirs, modes of transmission, and portals of entry. We also include public health topics such as emerging and reemerging diseases, zoonotic infections, and the role of anthropogenic factors, cultural factors, and public health measures in the emergence and spread of infectious disease.

The new Chapter 18, Immunization and Vaccines, highlights recent advances in vaccine development and expands discussion on the many vaccine formulations, designs, and additives and their advantages and disadvantages. An expanded section on vaccine development highlights basic research, correlates of protection, the testing and approval process, and the logistical and socio-cultural considerations required of vaccination programs.

The revised Chapter 13, Barrier Immunity: The Immunology of Mucosa and Skin, now includes a section on The Immune System of the Respiratory Tract. Both Chapter 13 and Chapter 14, The Immune Response in Space and Time, use SARS-CoV-2 as an example of how the immune system responds to a viral infection.

Five new feature boxes provide additional detail on pandemic-related topics:

Clinical Focus Box 4-3: Evading Innate Immunity: SARS CoV-2 Teases the Innate Immune System
Clinical Focus Box 17-1: Virus-induced Cytokine Storms and Inflammatory Syndromes
Evolution Box 17-2: Where Do Coronaviruses Come From?
Clinical Focus Box 17-3: Herd Immunity and the Moving Target of R0
Advances Box 18-1: The Relay Race to COVID-19 Vaccines


1 Overview of the Immune System
2 Cells, Organs, and Microenvironments of the Immune System
3 Recognition and Response
4 Innate Immunity
5 The Complement System
6 The Organization and Expression of Lymphocyte Receptor Genes
7 The Major Histocompatibility Complex and Antigen Presentation
8 T-Cell Development
9 B-Cell Development
10 T-Cell Activation, Differentiation, and Memory
11 B-Cell Activation, Differentiation, and Memory
12 Effector Responses: Cell- and Antibody-Mediated Immunity
13 The Barrier Immunity: Immunology of Mucosa and Skin
14 The Adaptive Immune Response in Time and Space
15 Allergy, Hypersensitivities, and Chronic Inflammation
16 Tolerance, Autoimmunity, and Transplantation
17 Infectious Disease and Public Health
18 Immunization and Vaccines
19 Immunodeficiency Disorders
20 Cancer and the Immune System