Ophthalmic Pathology: The Evolution of Current Concepts examines how our current understanding of morphologic disease, nomenclature and classification over the last century came about. The book explores the historical context and the modern trends of ocular nosology, emphasizing the science of disease classification. Chapters highlight major studies and developments surrounding approximately 50 disorders whose diagnoses are established by pathology, corresponding to a historical road map of current nomenclature, methods of disease classification, and the role of diagnostic morphology. Using a streamlined, highly illustrated format, this book provides a unique historic and evolutionary perspective into current views on the morphology of eye disease.


About Curtis E. Margo

Dr. Margo is an Ophthalmology Specialist in Tampa, FL, and has over 47 years of experience in the medical field. He graduated from Emory University School of Medicine medical school in 1974 and currently is Professor and Director of Ophthalmic Pathology at University of South Florida. His research interests include ocular pathology, clinical methods in ophthalmology, history of medicine and clinical epidemiology. He has published numerous books and book chapters, more than 300 articles and has over 5,000 citations. In 2019, Dr Curtis was the recipient of the Senior Achievement Award, by the American Academy of Ophthalmology.


Part I. Conjunctival and Ocular Neoplasia

1. Modern notion of cancer

2. In situ cancer

3. Epithelial tumors of conjunctiva

4. Conjunctival dysplasia and carcinoma in situ

5. Melanocytic tumors of conjunctiva

6. In situ melanoma

7. Uveal melanoma

8. Intraocular melanocytoma

9. Retinoblastoma

10. Retinocytoma

11. Ocular lymphoma

12. Medulloepithelioma

13. Hamartoma and choristoma



Part II. Conjunctival and Ocular Inflammations

1. Conjunctivitis

2. Sympathetic ophthalmia

3. Lens-induced inflammation

4. Toxocariasis

5. Intraocular granulomatous inflammation

6. Autoimmune inflammation of cornea and sclera

7. Reactive lymphoid hyperplasia



Part III. Ocular and Conjunctival Degenerations and Miscellaneous

1. Pterygium and pinguecula

2. Stromal dystrophies of the cornea

3. Corneal endothelial proliferations

4. Open-angle glaucoma

5. Cataracts and artificial intraocular lenses

6. Cavernous degeneration of optic nerve

7. Epiretinal membranes

8. Age-related macular degeneration

9. Papilledema



Part IV. Eyelid and Orbit

1. Basal cell carcinoma

2. Sebaceous carcinoma

3. Squamous cell carcinoma

4. Adnexal cancers

5. Mesenchymal tumors

6. Indolent lymphomas

7. High-grade lymphomas

8. Idiopathic inflammations

9. Rhabdomyosarcoma

10. Langerhans histiocytosis

11. Xanthomatous inflammations

12. Optic nerve meningioma

13. Optic nerve glioma

14. Germ cell tumors

15. Vascular tumors and malformations

16. The leukemias



Part V. The Influencers

1. Histochemistry

2. Electron microscopy

3. Immunohistochemistry

4. Adjuvant laboratory studies and molecular diagnostics

5. Cytology

6. Cancer grading and staging

7. Subspecialty training