This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners and trainees at all levels of experience and training. Covering all aspects of cytology, including gynecologic, non-gynecologic exfoliative, fine-needle aspiration, and imaging, it incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today's practice. Richly illustrated and easy to use, Diagnostic Pathology: Cytopathology, third edition, is a visually stunning, one-stop resource for every practicing pathologist, cytotechnologist, resident, cytopathology fellow, and cytotechnology student as an ideal day-to-day reference or as a reliable training resource.

Table of Contents
R. Mody, MD

8 Cytopreparation, Instrumentation, and Automated

Screening in Gynecologic Cytology

Michael J. Thrall, MD and Debora A. Smith, CT(ASCP)

10 Specimen Adequacy in Cervicovaginal Cytology

Dina R. Mody, MD and George G. Birdsong, MD

SECTION 2: BENIGN AND INFECTIOUS

CONDITIONS

14 Normal Pap Test

Nikolaos Chantziantoniou, BSc, ART(CSMLS), CFIAC and Dina R. Mody, MD

16 Infectious and Other Organisms in Pap Tests

Nikolaos Chantziantoniou, BSc, ART(CSMLS), CFIAC and Dina R. Mody, MD

18 Nonneoplastic Findings, Mimics, and Artifacts

Ekene I. Okoye, MD and Dina R. Mody, MD

SECTION 3: SQUAMOUS CELL

ABNORMALITIES AND MIMICS

28 Low-Grade Squamous Intraepithelial Lesion and

Mimics

Dina R. Mody, MD

30 High-Grade Squamous Intraepithelial Lesion and

Mimics

Dina R. Mody, MD and Ekene I. Okoye, MD

34 Atypical Squamous Cells of Undetermined

Significance

Nikolaos Chantziantoniou, BSc, ART(CSMLS), CFIAC and Dina R. Mody, MD

36 Atypical Squamous Cells, Cannot Rule Out High-

Grade Squamous Intraepithelial Lesion

Dina R. Mody, MD and Nikolaos Chantziantoniou, BSc, ART(CSMLS), CFIAC

38 Squamous Cell Carcinoma of Cervix, Variants and

Mimics

Dina R. Mody, MD

SECTION 4: GLANDULAR CELL

ABNORMALITIES AND MIMICS

46 Endocervical Adenocarcinoma In Situ, Variants and

Mimics

Dina R. Mody, MD

52 Endocervical Adenocarcinoma, Variants and Mimics

Dina R. Mody, MD

56 Adenocarcinoma, Minimal Deviation

Dina R. Mody, MD

58 Endometrial Cancers: Usual Types, Variants, and Mimics

Ekene I. Okoye, MD and Dina R. Mody, MD

64 Atypical Glandular Cells: Endocervicals, Endometrials, and Glandulars, NOS

Dina R. Mody, MD

70 Endometrial Cells in Pap Test and Glandular Cells Status Post Hysterectomy

Dina R. Mody, MD and Ekene I. Okoye, MD

SECTION 5: EXTINE

CARCINOMAS AND OTHER

MALIGNANCIES OF FEMALE GENITAL

TRACT

74 Extrauterine Carcinomas and Presentations in Cervicovaginal Cytology

Dina R. Mody, MD

76 Small Cell Neuroendocrine Carcinoma of Cervix

Dina R. Mody, MD

80 Other Uncommon Malignancies in Cervicovaginal Cytology

Dina R. Mody, MD

SECTION 6: MOLECULAR TESTING IN

GYNECOLOGIC CYTOLOGY

86 HPV and Other Molecular Testing in Gynecologic Cytology

Michael J. Thrall, MD

SECTION 7: DIRECTLY SAMPLED

ENDOMETRIAL CYTOLOGY

92 Directly Sampled Endometrial Cytology

Yuko Sugiyama, MD, PhD, FIAC and Dina R. Mody, MD

SECTION 8: ANAL CYTOLOGY

98 Anal Cytology

Michael J. Thrall, MD

Part II: Exfoliative Cytopathology

SECTION 1: RESPIRATORY TRACT

INCLUDING LUNG FNAS

102 Specimen Types in Respiratory Cytology and Adequacy Criteria

Michael J. Thrall, MD

104 Benign and Reactive Changes

Michael J. Thrall, MD

108 Pneumocystis Pneumonia and Mimics

Michael J. Thrall, MD

110 Fungal Organisms in Respiratory Cytology

Michael J. Thrall, MD

112 Parasitic Organisms in Respiratory Cytology

Michael J. Thrall, MD

114 Viral Infections (Cytomegalovirus, Herpesvirus, and Others)

Michael J. Thrall, MD

116 Mycobacteria and Other Bacterial Infections

Michael J. Thrall, MD

118 Sarcoidosis and Other Immune-Related Conditions

Michael J. Thrall, MD

120 Pulmonary Alveolar Proteinosis and Mimics

Michael J. Thrall, MD

122 Miscellaneous Findings Including Contaminants

Michael J. Thrall, MD

124 Adenocarcinoma

Michael J. Thrall, MD

128 Squamous Cell Carcinoma

Michael J. Thrall, MD

130 Small Cell Carcinoma

Michael J. Thrall, MD

132 Large Cell Neuroendocrine Carcinoma

Michael J. Thrall, MD

134 Carcinoid and Atypical Carcinoid

Michael J. Thrall, MD

136 Rare Benign and Low Malignant Potential Tumors

Michael J. Thrall, MD

138 Rare Malignant Tumors

Michael J. Thrall, MD

140 Pulmonary Lymphoma

Michael J. Thrall, MD

142 Pulmonary Metastasis

Michael J. Thrall, MD

SECTION 2: GASTROINTESTINAL TRACT

146 Specimen Types in Gastrointestinal Cytology and Normal Cellular Components

Blythe K. Gorman, MD and Dina R. Mody, MD

148 Parasitic Infections

Blythe K. Gorman, MD and Dina R. Mody, MD

150 Viral Infections

Blythe K. Gorman, MD and Dina R. Mody, MD

152 Esophagitis and Barrett Esophagus

Blythe K. Gorman, MD and Dina R. Mody, MD

154 Esophageal Adenocarcinoma

Blythe K. Gorman, MD and Dina R. Mody, MD

156 Esophageal Squamous Cell Carcinoma

Blythe K. Gorman, MD

158 Gastritis and Intestinal Metaplasia

Blythe K. Gorman, MD and Dina R. Mody, MD

160 Gastric Adenocarcinoma

Blythe K. Gorman, MD and Dina R. Mody, MD

162 Gastric Lymphoma

Blythe K. Gorman, MD and Dina R. Mody, MD

164 Ampulla/Bile Duct/Pancreatic Duct Reactive

Changes

Blythe K. Gorman, MD and Dina R. Mody, MD

166 Ampulla/Bile Duct/Pancreatic Duct Adenocarcinoma

Blythe K. Gorman, MD and Dina R. Mody, MD

168 Colorectal Adenoma/Carcinoma

Blythe K. Gorman, MD and Dina R. Mody, MD

170 Neuroendocrine Tumor/Carcinoma

Blythe K. Gorman, MD and Dina R. Mody, MD

172 Spindle Cell Neoplasms of Gastrointestinal Tract,

Including Gastrointestinal Stromal Tumors

Blythe K. Gorman, MD and Dina R. Mody, MD

SECTION 3: CEREBROSPINAL FLUID

176 Normal Cerebrospinal Fluid and Contamination by Normal Elements

Hidehiro Takei, MD and Michael J. Thrall, MD

180 Infectious Meningitis

Hidehiro Takei, MD and Michael J. Thrall, MD

182 Aseptic and Mollaret Meningitis

Hidehiro Takei, MD and Michael J. Thrall, MD

184 Subarachnoid Hemorrhage

Hidehiro Takei, MD and Michael J. Thrall, MD

186 Neurodegenerative Diseases

Hidehiro Takei, MD and Michael J. Thrall, MD

188 Primary Brain Tumors

Hidehiro Takei, MD and Michael J. Thrall, MD

190 Leukemia and Lymphoma

Hidehiro Takei, MD and Michael J. Thrall, MD

192 Metastasis in CSF

Hidehiro Takei, MD and Michael J. Thrall, MD

SECTION 4: PLEURAL, PERITONEAL,

PERICARDIAL, AND PELVIC FLUID AND

WASHINGS

196 Normal Cellular Components, Reactive Mesothelial Proliferations, and Reporting Terminology

Donna M. Coffey, MD and Michael J. Thrall, MD

200 Infectious Conditions

Donna M. Coffey, MD and Michael J. Thrall, MD

202 Autoimmune Diseases

Donna M. Coffey, MD and Michael J. Thrall, MD

204 Malignant Effusion, Mesothelioma

Donna M. Coffey, MD and Michael J. Thrall, MD

208 Malignant Effusion, Carcinomas

Donna M. Coffey, MD and Michael J. Thrall, MD

212 Malignant Effusion, Sarcomas

Donna M. Coffey, MD, Nour Sneige, MD, and Michael J. Thrall, MD

214 Lymphoid Effusions and Lymphomas

Donna M. Coffey, MD and Michael J. Thrall, MD

216 Primary Effusion Lymphoma

John M. Stewart, MD, PhD and Michael J. Thrall, MD

218 Endometriosis and Endosalpingiosis

Donna M. Coffey, MD, Nour Sneige, MD, and Michael J.

Thrall, MD

220 Ovarian Neoplasms

Donna M. Coffey, MD and Michael J. Thrall, MD

222 Immunocytochemistry, Histochemistry, and Other Ancillary Techniques

Donna M. Coffey, MD and Michael J. Thrall, MD

SECTION 5: URINARY CYTOLOGY

228 Normal Urinary Cytology, Specimen Types, and Reporting Terminology

Michael J. Thrall, MD and Rose Anton, MD

232 Ileal Conduit Specimens

Rose Anton, MD and Michael J. Thrall, MD

234 Noninfectious Benign Conditions

Rose Anton, MD and Michael J. Thrall, MD

236 Infectious Benign Conditions

Rose Anton, MD and Michael J. Thrall, MD

238 Reactive Urothelial Changes

Rose Anton, MD and Michael J. Thrall, MD

240 Low-Grade Urothelial Lesions

Rose Anton, MD and Michael J. Thrall, MD

242 High-Grade Urothelial

Dysplasia/Carcinoma/Carcinoma In Situ

Rose Anton, MD and Michael J. Thrall, MD

244 Squamous Cell Carcinoma of Urinary Bladder

Rose Anton, MD, Nour Sneige, MD, and Michael J. Thrall, MD

246 Adenocarcinoma of Urinary Bladder

Rose Anton, MD, Nour Sneige, MD, and Michael J. Thrall, MD

248 Other Malignancies in Urinary Cytology

Rose Anton, MD, Nour Sneige, MD, and Michael J. Thrall, MD

250 Renal Pelvic Cytology

Blythe K. Gorman, MD and Michael J. Thrall, MD

252 Ancillary Testing, UroVysion, and Others

Gene Landon, MD, Nancy P. Caraway, MD, and Michael J.

Thrall, MD

Part III: Fine-Needle Aspiration, Superficial

SECTION 1: OVERVIEW

256 Superficial Aspiration Technique

Rose Anton, MD and Dina R. Mody, MD

SECTION 2: THYROID GLAND

260 Ultrasound-Guided Thyroid Fine-Needle Aspiration

Paula J. Woodward, MD

266 Thyroid Fine-Needle Aspiration Reporting Terminology and Specimen Adequacy

Dina R. Mody, MD

268 Adenomatous (Benign Follicular) Nodule

Mojgan Amrikachi, MD and Dina R. Mody, MD

270 Chronic Lymphocytic/Hashimoto Thyroiditis

Mojgan Amrikachi, MD and Dina R. Mody, MD

272 Granulomatous Thyroiditis

Mojgan Amrikachi, MD and Dina R. Mody, MD

274 Graves Disease/Diffuse Toxic Goiter

Mukul K. Divatia, MD and Dina R. Mody, MD

276 Pigmented Thyroid Lesions and Crystals

Mukul K. Divatia, MD and Dina R. Mody, MD

278 Atypia of Undetermined Significance/Follicular

Lesion of Undertermined Significance

Dina R. Mody, MD

282 Follicular Neoplasm/Suspicious for a Follicular Neoplasm

Dina R. Mody, MD

286 Follicular Neoplasm, Hürthle Cell (Oncocytic) Type

Mojgan Amrikachi, MD and Dina R. Mody, MD

288 Papillary Thyroid Carcinoma, Classic Variant

Mojgan Amrikachi, MD and Dina R. Mody, MD

292 Papillary Thyroid Carcinoma Variants

Mojgan Amrikachi, MD and Dina R. Mody, MD

300 Medullary Thyroid Carcinoma

Mojgan Amrikachi, MD and Dina R. Mody, MD

304 Poorly Differentiated Thyroid Carcinoma

Susan L. Haley, MD and Dina R. Mody, MD

306 Anaplastic Thyroid Carcinoma

Susan L. Haley, MD and Dina R. Mody, MD

308 Thyroid Lymphoma

Susan L. Haley, MD and Dina R. Mody, MD

310 Metastatic Carcinoma to Thyroid

Susan L. Haley, MD and Dina R. Mody, MD

312 Other Nonneoplastic and Neoplastic Thyroid Lesions Encountered on Thyroid FNA

Mojgan Amrikachi, MD and Dina R. Mody, MD

SECTION 3: PARATHYROID GLAND

320 Parathyroid Cyst, Adenoma, and Carcinoma

Susan L. Haley, MD, Rose Anton, MD, and Dina R. Mody, MD

SECTION 4: LYMPH NODES

OVERVIEW

326 Indications for Aspiration and Techniques

Rose Anton, MD and Dina R. Mody, MD

328 FNA Sample Prep and Triage in Evaluating Suspected Lymphoma

John M. Stewart, MD, PhD and Savitri Krishnamurthy, MD

BENIGN, INFECTIOUS, AND REACTIVE HYPERPLASIA

330 Inflammatory and Reactive Lymphoid Hyperplasia

Rose Anton, MD and Savitri Krishnamurthy, MD

332 Granulomatous Lymphadenitis, Infectious and Sarcoid

Rose Anton, MD and Savitri Krishnamurthy, MD

336 Rosai-Dorfman Disease

Rose Anton, MD, John M. Stewart, MD, PhD, and Savitri

Krishnamurthy, MD

METASTATIC MALIGNANCIES

338 Metastatic Malignancies (Carcinoma, Melanoma)

Rose Anton, MD and Dina R. Mody, MD

340 HPV-Positive Head and Neck Squamous Cell

Carcinoma

Mary R. Schwartz, MD and Dina R. Mody, MD

NODAL B-CELL LYMPHOMA

344 Small Lymphocytic Lymphoma

Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD

346 Lymphoplasmacytic Lymphoma

Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD

348 Mantle Cell Lymphoma

Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD

350 Nodal Marginal Zone Lymphoma

Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD

352 Follicular Lymphoma

Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD

354 Burkitt Lymphoma

Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD

356 Large B-Cell Lymphoma

Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD

EXTRANODAL B-CELL LYMPHOMA

358 Plasmacytoma

Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD

360 Mediastinal Large B-Cell Lymphoma

Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD

362 Plasmablastic Lymphoma

John M. Stewart, MD, PhD, Nancy P. Caraway, MD, and Savitri Krishnamurthy, MD

T-CELL LYMPHOMA

364 Peripheral T-Cell Lymphoma

Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD

366 Mycosis Fungoides

Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD

368 Angioimmunoblastic Lymphoma

Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD

370 ALK(+) Anaplastic Large Cell Lymphoma

Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD

372 T-Cell Lymphoblastic Lymphoma

Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD

HODGKIN LYMPHOMA

374 Nodular Lymphocyte-Predominant Hodgkin Lymphoma

Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD

376 Classical Hodgkin Lymphoma

Nancy P. Caraway, MD, John M. Stewart, MD, PhD, and Savitri Krishnamurthy, MD

SECTION 5: SALIVARY GLAND

OVERVIEW

380 Approach to Interpretation of Salivary Gland Aspiration Biopsies and Reporting Terminology (Milan System)

Dina R. Mody, MD

BENIGN LESIONS

384 Normal Salivary Gland and Sialadenitis on Aspiration

Rose Anton, MD and Dina R. Mody, MD

386 Cysts

Rose Anton, MD and Dina R. Mody, MD

388 Pleomorphic Adenoma

Rose Anton, MD and Dina R. Mody, MD

390 Warthin Tumor

Rose Anton, MD and Dina R. Mody, MD

392 Myoepithelioma

Rose Anton, MD and Dina R. Mody, MD

393 Oncocytoma, Salivary Gland

Dina R. Mody, MD

MALIGNANT NEOPLASMS

394 Adenoid Cystic Carcinoma

Rose Anton, MD and Dina R. Mody, MD

396 Acinic Cell Carcinoma

Rose Anton, MD and Dina R. Mody, MD

398 Mucoepidermoid Carcinoma

Rose Anton, MD and Dina R. Mody, MD

400 Basaloid Neoplasms, Benign and Malignant

Hidehiro Takei, MD and Dina R. Mody, MD

402 Carcinoma Ex Pleomorphic Adenoma

Hidehiro Takei, MD and Dina R. Mody, MD

404 Adenocarcinoma, Not Otherwise Specified

Hidehiro Takei, MD and Dina R. Mody, MD

406 Polymorphous Low-Grade Adenocarcinoma

Hidehiro Takei, MD and Dina R. Mody, MD

408 Salivary Duct Carcinoma

Hidehiro Takei, MD and Dina R. Mody, MD

410 Secretory Carcinoma

Michael J. Thrall, MD

412 Myoepithelial Carcinoma

Shubhada Kane, MD and Michael J. Thrall, MD

413 Cribriform Adenocarcinoma

Shubhada Kane, MD and Michael J. Thrall, MD

of Fine-Needle Aspiration of Breast, Techniques

and Triple Test

Savitri Krishnamurthy, MD

BENIGN BREAST LESIONS

422 Inflammatory and Granulomatous Conditions

Savitri Krishnamurthy, MD

424 Fat Necrosis

Savitri Krishnamurthy, MD

426 Nonproliferative and Proliferative Changes in Breast

Savitri Krishnamurthy, MD

430 Radial Scar/Complex Sclerosing Lesion

Savitri Krishnamurthy, MD

432 Gynecomastia

Savitri Krishnamurthy, MD

434 Mucocele-Like Lesion

Savitri Krishnamurthy, MD

BENIGN NEOPLASMS

436 Fibroadenoma

Savitri Krishnamurthy, MD

440 Granular Cell Tumor of Breast

Savitri Krishnamurthy, MD

442 Papillary Neoplasms

Savitri Krishnamurthy, MD

448 Myofibroblastoma, Mammary

Savitri Krishnamurthy, MD

MALIGNANT NEOPLASMS

450 Ductal Carcinoma and Variants of Invasive Mammary

Carcinoma

Savitri Krishnamurthy, MD

458 Lobular Carcinoma

Savitri Krishnamurthy, MD

460 Phyllodes Tumor

Savitri Krishnamurthy, MD

462 Angiosarcoma and Other Sarcomas

Savitri Krishnamurthy, MD

466 Lymphomas and Metastatic Tumors

Savitri Krishnamurthy, MD

NIPPLE DISCHARGE

470 Cytology Specimens for Risk Assessment of Breast

Cancer

Savitri Krishnamurthy, MD

SECTION 7: SKIN AND SUBCUTANEOUS

CYTOLOGY

474 Cutaneous and Adnexal Cytology

Mary R. Schwartz, MD and Dina R. Mody, MD

Part IV: Fine-Needle Aspiration,

Deep Organs and Tissues

SECTION 1: OVERVIEW

480 Techniques and Modalities of Deep Aspiration

Biopsies

Paula J. Woodward, MD and Ashraf Thabet, MD

SECTION 2: MEDIASTINUM

OVERVIEW

486 Anatomic Compartments and Constituent Tumors

Ming Guo, MD and Savitri Krishnamurthy, MD

NONNEOPLASTIC LESIONS

488 Mediastinal Cysts and Inflammatory Lesions

Ming Guo, MD and Savitri Krishnamurthy, MD

NEOPLASMS

490 Thymoma

Ming Guo, MD and Savitri Krishnamurthy, MD

492 Thymic Carcinoma

Ming Guo, MD and Savitri Krishnamurthy, MD

494 Germ Cell Tumors

Ming Guo, MD and Savitri Krishnamurthy, MD

496 Neurogenic Tumors

Ming Guo, MD and Savitri Krishnamurthy, MD

498 Metastatic Tumors of Mediastinum

Ming Guo, MD and Savitri Krishnamurthy, MD

SECTION 3: LIVER

OVERVIEW

502 Cytology of Normal Liver

Rose Anton, MD, Nour Sneige, MD, and Dina R. Mody, MD

504 Inflammatory and Infectious Conditions of Liver

Rose Anton, MD, Nour Sneige, MD, and Dina R. Mody, MD

BENIGN HEPATIC NEOPLASMS

506 Hepatocellular Adenoma

Rose Anton, MD, Nour Sneige, MD, and Dina R. Mody, MD

508 Focal Nodular Hyperplasia

Rose Anton, MD, Nour Sneige, MD, and Dina R. Mody, MD

510 Hemangioma, Liver

Rose Anton, MD, Nour Sneige, MD, and Dina R. Mody, MD

MALIGNANT NEOPLASMS

512 Hepatocellular Carcinoma

Rose Anton, MD, Nour Sneige, MD, and Dina R. Mody, MD

514 Hepatoblastoma

Rose Anton, MD, Nour Sneige, MD, and Dina R. Mody, MD

516 Liver Metastasis

Rose Anton, MD, Nour Sneige, MD, and Dina R. Mody, MD

SECTION 4: KIDNEY

OVERVIEW

520 Cytology of Normal Kidney

Yimin Ge, MD

BENIGN LESIONS AND NEOPLASMS

522 Renal Cysts

Yimin Ge, MD

524 Angiomyolipoma

Yimin Ge, MD

526 Oncocytoma, Kidney

Yimin Ge, MD

528 Metanephric Adenoma

Yimin Ge, MD and Jun Zhang, MD, MS

530 Metanephric Stromal Tumor

Yimin Ge, MD and Norma Quintanilla, MD

531 Xanthogranulomatous Pyelonephritis/Malakoplakia

Yimin Ge, MD

MALIGNANT NEOPLASMS

532 Clear Cell Renal Cell Carcinoma

Yimin Ge, MD

536 Papillary Renal Cell Carcinoma

Yimin Ge, MD

538 Clear Cell Papillary Renal Cell Carcinoma

Michael J. Thrall, MD

540 Chromophobe Renal Cell Carcinoma

Yimin Ge, MD

542 Collecting Duct Carcinoma

Yimin Ge, MD and Jun Zhang, MD, MS

543 Renal Medullary Carcinoma

Yimin Ge, MD

544 Mucinous Tubular and Spindle Cell Carcinoma of Kidney

Yimin Ge, MD

545 Carcinoid Tumor

Yimin Ge, MD

546 Primary Renal Sarcomas in Adults

Yimin Ge, MD and Jun Zhang, MD, MS

547 Renal Lymphomas

Yimin Ge, MD and Jun Zhang, MD, MS

548 Nephroblastoma (Wilms Tumor)

Yimin Ge, MD, Jun Zhang, MD, MS, and Norma

Quintanilla, MD

550 Clear Cell Sarcoma of Kidney

Yimin Ge, MD and Norma Quintanilla, MD

552 Congenital Mesoblastic Nephroma

Yimin Ge, MD and Norma Quintanilla, MD

554 Rhabdoid Tumor of Kidney

Yimin Ge, MD and Norma Quintanilla, MD

555 Metastatic Tumors to Kidney

Yimin Ge, MD

TUMORS OF RENAL PELVIS

556 Urothelial Carcinoma

Yimin Ge, MD

SECTION 5: ADRENAL GLAND

OVERVIEW

560 Cytology of Normal Adrenal Gland

Yimin Ge, MD

ADRENAL CORTICAL LESIONS

562 Adrenal Cortical Adenoma

Yimin Ge, MD

564 Adrenal Cortical Carcinoma

Yimin Ge, MD

566 Metastatic Tumors to Adrenal Gland

Yimin Ge, MD

ADRENAL MEDULLARY LESIONS

568 Pheochromocytoma

Yimin Ge, MD

SECTION 6: PANCREAS

OVERVIEW

572 Cytology of Normal Pancreas

Uma Kundu, MD and Dina R. Mody, MD

574 Pancreatic Cytology Reporting Terminology, Cyst

Evaluation

Dina R. Mody, MD and Mary R. Schwartz, MD

NONNEOPLASTIC LESIONS

576 Pancreatitis

Uma Kundu, MD and Dina R. Mody, MD

578 Lymphoepithelial Cyst of Pancreas

Dina R. Mody, MD

579 Intra- and Peripancreatic Splenules

Dina R. Mody, MD

NEOPLASMS

580 Serous Microcystic Adenoma

Uma Kundu, MD and Savitri Krishnamurthy, MD

582 Mucinous Cystic Neoplasm

Uma Kundu, MD and Savitri Krishnamurthy, MD

584 Intraductal Papillary Mucinous Neoplasm

Uma Kundu, MD and Savitri Krishnamurthy, MD

586 Solid Pseudopapillary Neoplasm

Gene Landon, MD and Savitri Krishnamurthy, MD

588 Pancreatic Neuroendocrine Tumor

Gene Landon, MD and Savitri Krishnamurthy, MD

590 Pancreatic Ductal Adenocarcinoma

Gene Landon, MD and Savitri Krishnamurthy, MD

592 Unusual Variants of Ductal Carcinoma

Savitri Krishnamurthy, MD

596 Acinar Cell Carcinoma

Savitri Krishnamurthy, MD

598 Lymphoma and Secondary Tumors of Pancreas

Savitri Krishnamurthy, MD

SECTION 7: BONE

OVERVIEW

602 Approach to Cytologic/Small Biopsy Diagnosis of

Primary Bone Tumors

Dina R. Mody, MD

NEOPLASMS

604 Chondromas of Bone and Soft Tissue

Mukul K. Divatia, MD and Dina R. Mody, MD

606 Chondroblastoma

Dina R. Mody, MD

608 Giant Cell Tumor

Dina R. Mody, MD

610 Osteoblastoma

Dina R. Mody, MD

612 Adamantinoma

Dina R. Mody, MD

614 Langerhans Cell Histiocytosis

Dina R. Mody, MD

616 Chordoma

Dina R. Mody, MD

618 Osteosarcoma

Savitri Krishnamurthy, MD

622 Chondrosarcoma

Savitri Krishnamurthy, MD

626 Ewing Sarcoma

Savitri Krishnamurthy, MD

630 Bone Lymphoma

Dina R. Mody, MD

632 Metastatic Tumors of the Bone

Dina R. Mody, MD

SECTION 8: SOFT TISSUE

OVERVIEW

636 Approach to Cytologic/Small Biopsy Diagnosis of Primary Soft Tissue Lesions

Dina R. Mody, MD

ADIPOCYTIC TUMORS

638 Benign Adipose Tissue Tumors

Uma Kundu, MD and Savitri Krishnamurthy, MD

640 Liposarcoma

Uma Kundu, MD and Savitri Krishnamurthy, MD

FIBROBLASTIC/MYOFIBROBLASTIC LESIONS

644 Fibrosarcoma

Uma Kundu, MD and Savitri Krishnamurthy, MD

646 Myofibroblastoma

Uma Kundu, MD and Savitri Krishnamurthy, MD

648 Low-Grade Myofibroblastic Sarcoma

Uma Kundu, MD and Savitri Krishnamurthy, MD

FIBROHISTIOCYTIC TUMORS

650 Giant Cell Tumor of Tendon Sheath

Uma Kundu, MD and Savitri Krishnamurthy, MD

652 Undifferentiated Pleomorphic Sarcoma

Uma Kundu, MD and Savitri Krishnamurthy, MD

TUMORS OF MUSCLE ORIGIN

654 Smooth Muscle Tumors

Gene Landon, MD and Savitri Krishnamurthy, MD

656 Skeletal Muscle Tumors

Gene Landon, MD and Savitri Krishnamurthy, MD

VASCULAR TUMORS

660 Hemangioma, Soft Tissue

Gene Landon, MD and Michael J. Thrall, MD

662 Epithelioid Hemangioendothelioma

Gene Landon, MD and Michael J. Thrall, MD

664 Angiosarcoma

Gene Landon, MD and Savitri Krishnamurthy, MD

OTHER TUMORS

666 Other Reactive and Neoplastic Soft Tissue Entities

Dina R. Mody, MD

668 Mesenchymal Chondrosarcoma

Dina R. Mody, MD

669 Solitary Fibrous Tumor

Dina R. Mody, MD

670 Intramuscular Myxoma

Gene Landon, MD and Savitri Krishnamurthy, MD

672 Synovial Sarcoma

Gene Landon, MD and Savitri Krishnamurthy, MD

674 Epithelioid Sarcoma

Gene Landon, MD and Savitri Krishnamurthy, MD

676 Alveolar Soft Part Sarcoma

Uma Kundu, MD and Savitri Krishnamurthy, MD

678 Clear Cell Sarcoma of Soft Tissue

Uma Kundu, MD and Savitri Krishnamurthy, MD

680 Desmoplastic Small Round Cell Tumor

Uma Kundu, MD and Savitri Krishnamurthy, MD

SECTION 9: OPHTHALMIC AND

NEUROPATHOLOGY

684 Approach to Ophthalmic Cytology

Patricia Chévez-Barrios, MD

688 Ophthalmic Cytopathology, Infectious

Patricia Chévez-Barrios, MD

692 Ophthalmic Cytopathology, Neoplastic

Patricia Chévez-Barrios, MD

698 Neuropathology Squash Preparations, Infectious

Andreana L. Rivera, MD, Suzanne Z. Powell, MD, and Hidehiro Takei, MD

702 Neuropathology Squash Preparations, Glial Neoplasms

Suzanne Z. Powell, MD, Andreana L. Rivera, MD, and Hidehiro Takei, MD

706 Neuropathology Squash Preparations, Nonglial Neoplasms

Andreana L. Rivera, MD, Suzanne Z. Powell, MD, and Hidehiro Takei, MD

Part V: Management and Ancillary

Testing

SECTION 1: CYTOPREPARATORY AND

QUALITY MANAGEMENT

712 Cytopreparatory Techniques and Instrumentation in Nongynecologic Cytology

Debora A. Smith, CT(ASCP) and Dina R. Mody, MD

718 Quality Improvement and Laboratory Management for Cytopathology

Debora A. Smith, CT(ASCP) and Dina R. Mody, MD

SECTION 2: ANCILLARY TESTING

726 Immunocytochemistry

Savitri Krishnamurthy, MD

730 Molecular Techniques

Savitri Krishnamurthy, MD