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Over the last 18 years, there have been many advances in the field of intraoperative monitoring. This new edition of Neurophysiology in Neurosurgery: A Modern Approach provides updates on the original techniques, as well as other more recent methodologies that may either prove beneficial or are commonly used in neuromonitoring. The purpose of this book is to describe the integration of neuromonitoring with surgical procedures. Each methodology is discussed in detail as well as chapters describing how those methodologies are applied to multiple surgical procedures and the evidence used to support those uses. The second edition features a surgical procedure section, which focuses on specific surgical procedures and the type of monitoring used during these procedures. The original chapters have been updated, expanded, and the structure modified to ensure the book is beneficial to both physiologists and surgeons. This book is written for neurosurgeons, neurophysiologists, neurologists, anesthesiologists, interventional neuroradiologists, orthopedic surgeons, and plastic surgeons.

Provides a valuable educational tool that describes the theoretical and practical aspects of intraoperative monitoring through example
Presents in-depth descriptions of the most advanced techniques in intraoperative neurophysiological monitoring and mapping
Features a surgical procedures section that focuses on specific surgical procedures and the type of monitoring used during these procedures

Neurosurgeons, neurophysiologists, neurologists, anesthesiologists, interventional neuroradiologists, orthopedic surgeons, and plastic surgeons


Jay L. Shils, Ph.D., D.ABNM, FASNM, FACNS is currently the director of intraoperative neurophysiological monitoring at Rush University Medical School and an Associate Professor in the department of Anesthesiology at Rush Medical Center. He received his Bachelor of Science degree in electrical engineering from Syracuse University, and both his masters and PhD in Bio-Engineering at The University of Pennsylvania using with his thesis dissertation subject The Bispectrum of the Human Electroencephalogram to investigate interactions in the visual system and study EEG in epilepsy. Dr. Shils has been involved in intraoperative neuromonitoring since 1994 specializing in microelectrode neurophysiology for movement disorders. Dr. Shils is the co-editor of two neuromodulation related books which is one of his primary interests and the first edition of this book. Dr, Shils is a past president of the ASNM and the ISIN and is the founding secretary of the ISIN. Dr. Shils is the present secretary of the ASNM. Over the years Dr. Shils has presented at over 100 national and international has published on MER, DBS, neuromodulation, and intraoperative monitoring techniques.

Director of Intraoperative Neurophysiological Monitoring and Associate Professor in Anesthesiology, Rush University Medical Center, Chicago, IL, USA.

Francesco Sala is Professor and Chair of Neurosurgery at the University of Verona, in Italy. His main clinical and research interests are Pediatric Neurosurgery and Intraoperative Neurophysiology. In 1998-1999 he was Clinical Fellow in Intraoperative Neurophysiology, under the supervision of Dr. Vedran Deletis, at the Institute for Neurology and Neurosurgery in New York. Upon his return to Italy, he established the Intraoperative Neurophysiology Unit at the Institute of Neurosurgery in Verona where, in the past twenty years, more than 3000 elective neurosurgical procedures have been performed under neurophysiological guidance. In 2005 he was one of the co-founders of the International Society for Intraoperative Neurophysiology, where he has served as Secretary (2009-2011), Chairman of the Education Committee (2011-2013), and President (2013-2015). Prof. Sala is particularly committed to the training of young neurosurgeons and the development of intraoperative neurophysiology in the global neurosurgical community. Since 2010 he teaches at the Training Courses of the European Association of Neurosurgical Societies (EANS), and he's currently an Executive Board member of the EANS. In 2016 he was appointed as first Chair of the Neuromonitoring Committee of the World Federation of Neurosurgical Societies.

Professor and Chair of Neurosurgery, Department of Neurosciences, Biomedicine and Movement Sciences, Verona University Hospital, Italy.

Kathleen Seidel, is board certified neurosurgeon, staff physician and associate professor of the Department of neurosurgery at the Inselspital, University Hospital Bern, Switzerland. Since 2008 at the Inselspital, she has established the unit of intraoperative neurophysiology. After a fellowship in ION with Vedran Deletis in New York, she is providing training to other professionals, hosting international observers and focusing on advance of ION modalities to improve patient safety in technical high-risk surgeries. Providing expertise in neurosurgery and intraoperative neurophysiology, she is a routinely invited speaker at international courses and congresses. She has published numerous ION papers and key papers concerning subcortical brain mapping and mapping of the spinal cord. Currently, she serves as the head of the scientific committee of the society of intraoperative neurophysiology (ISIN). Recently, she was awarded with the prestigious Theodor Kocher Prize of Bern University, which honors its best academics across its faculties for their exceptional and innovative scientific achievements.

Head of the Unit of Intraoperative Neurophysiology. Attending Physician and Associate Professor, Department of Neurosurgery, Inselspital, Bern University Hospital, Bern, Switzerland.

PART I: Introduction to Intraoperative Neurophysiology
a. Historical perspective

PART II: Intraoperative Neurophysiology: Neurophysiological perspective
a. Neurophysiology of the motor system: basics and IOM techniques
b. Neurophysiology of the somatosensory system: basics and IOM techniques
c. Neurophysiology of the auditory system: basics and IOM techniques
d. Neurophysiology of the visual system: basics and IOM techniques
e. Neurophysiology of language and other cognitive systems
f. Neurophysiology of critical brainstem and spine reflexes

PART III: Safety and Anesthesia in Intraoperative Neurophysiology
a. Safety
b. Principles of Anesthesia

PART IV: Intraoperative Neurophysiology: Surgical perspective
a. Supratentorial surgery
b. Infratentorial surgery
c. Spine and Spinal Cord Surgery
d. Surgery of the Peripheral Nervous System
e. Vascular Neurosurgery
f. Functional Neurosurgery

Part V: Conclusions on current challenges of neuromonitoring
a. Analysis of Costs and Benefits
b. Evidence Based Medicine and Intraoperative Neurophysiology
c. Current trends and threats
Academic Press Ltd.
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