Landau-Kleffner syndrome (LKS) is a rare childhood neurological syndrome. It is characterised by a sudden or gradual loss of ability to understand of express language (aphasia) and usually occurs inchildren between the ages of 3 and 7 years. Rolandic epilepsy is the most common epilepsy syndrome in childhood with involvement of the oropharyngeal manifestations, hypersalivation and arrest ofspeech. These two syndromes are considered to be aspects of the epilepsy-aphasia spectrum"" with common rolandic epilepsy being the mildest form and LKS the most severe.

CONTENTS:
1. Introduction
2. History of Landau-Kleffner syndrome (LKS) 3. Classifications issues
4. Speech perceptor and brain organization of language: relevant features for LKS and EAS
5. The different clinical facts of LKS
6. Developmental aspects of LKS / EAS and the overlap with developmental language disorder and autism spectum disorder
7. Evolution of LKS, short - mid and long term outcome
8. From rolandic epicepsy to LKS
9. Laboratory (eeg, brain imaging, genetics and neuroinmunology) investigations for LKS / EAS
10. Physiopathology of speech, language and other proonged epileptic dysfunction in LKS, ecsws and related syndromes
11. Functional neuroimaging investigations in idiopathic focal epilepsies of chilhook with cognitive and behavioural impairment
12. Drug management of cognitive impairements in LKS and other EAS syndromes
13. Speech and language, educational and phychological remediation
14. Personal testimonies and unpublished cases
15. Sumary and conclusions