This comprehensive handbook on the implementation of short course radiotherapy for the treatment of breast cancer is intended as an up-to-date resource for the clinician. The book opens with a series of chapters on underlying principles and diverse relevant topics, including pathologic anatomy of early-stage breast cancer, radiobiology of accelerated breast irradiation, quality assurance and radiation safety, surgical considerations in partial breast irradiation, and impact of oncoplastic surgery on adjuvant radiotherapy. Individual sections are then devoted to hypofractionated whole breast radiotherapy, accelerated partial breast irradiation, and intraoperative radiotherapy. Each section includes details of patient selection, physics, techniques, data, and toxicity. The reader is provided with clear guidance on the appropriate use of accelerated forms of adjuvant radiotherapy for treatment of early-stage breast cancer and on various emerging treatment approaches.
APBI: History, Rationale, and Controversies
White, Julia
Pages 3-21
Pathological Anatomy of Early-Stage Breast Cancer: Defining the Target
Kirby, Anna M.
Pages 23-38
The Radiobiology of Breast Radiotherapy
Khan, Atif J. (et al.)
Pages 39-52
Quality Assurance and Radiation Safety for Breast Irradiation
Thomadsen, Bruce (et al.)
Pages 53-75
Surgical Considerations in Partial-Breast Irradiation
Beitsch, Peter D.
Pages 77-95
Impact of Oncoplastic Surgery on Adjuvant Radiation Therapy
Vora, Nayana L. (et al.)
Pages 97-104
Comparison of True Cost Between Modalities in a Changing American Healthcare System
Schutzer, Matthew E. (et al.)
Pages 105-118
Patient Selection for Hypofractionated Whole Breast Radiation Therapy for Treatment of Early-Stage Breast Cancer
Freedman, Gary M.
Pages 121-135
Physics of Hypofractionated Whole Breast Irradiation
Kainz, Kristofer (et al.)
Pages 137-152
New York University Experience and Prone Positioning
Balogun, Onyinye (et al.)
Pages 153-167
The Canadian Experience with Hypofractionation
Arsenault, Julie (et al.)
Pages 169-180
United Kingdom Experience: Clinical Trial Evolution, Techniques, Data, and Toxicity
Yarnold, John (et al.)
Pages 181-193
Patient Selection for Accelerated Partial Breast Irradiation (APBI)
Cuttino, Laurie W.
Pages 197-206
Physics of APBI
Todor, Dorin A.
Pages 207-227
Overview of Outcomes with Accelerated Partial Breast Irradiation
Shah, Chirag (et al.)
Pages 229-244
The Evolution of Brachytherapy Techniques and the Current Arizona Approach
Kuske, Robert R.
Pages 245-271
Intracavitary Brachytherapy: Techniques, Data, Toxicity
Patel, Rakesh R.
Pages 273-283
External-Beam Accelerated Partial Breast Irradiation
Sabolch, Aaron (et al.)
Pages 285-302
Patient Selection for IORT
Harris, Eleanor (et al.)
Pages 305-315
Physics of Intraoperative Radiotherapy for the Breast
Mourtada, Firas
Pages 317-325
A Risk-Adapted Approach to Breast Radiation Using Targeted Intraoperative Radiotherapy (TARGIT)
Vaidya, Jayant S. (et al.)
Pages 327-346
Intraoperative Technique with Electrons
Lemanski, Claire (et al.)
Pages 347-359
Ultrashort Courses of Breast Radiotherapy
Khan, Atif J. (et al.)
Pages 363-372
Breast Conservation Therapy Without Capsular Contracture in Augmented Women Using Interstitial Brachytherapy
Kuske, Robert R.
Pages 373-385
Noninvasive Image-Guided Breast Brachytherapy (NIBB)
Hepel, Jaroslaw T.
Pages 387-402
APBI (Accelerated Partial Breast Irradiation) for in Breast Recurrence Following WBI
Hanoun-Levi, Jean-Michel
Pages 403-413
Preoperative Partial Breast
Mowery, Yvonne M. (et al.)
Pages 415-440
Hypofractionated Regional Nodal Irradiation for Breast Cancer
Poppe, Matthew (et al.)
Pages 441-464
Stereotactic Treatment for Oligometastatic Breast Cancer
Chmura, Steven J. (et al.)
Pages 467-481
Hypofractionated Palliative Radiation Therapy for Breast Cancer
Lutz, Stephen T.
Pages 483-491