Fully updated throughout, the second edition of the Manual of Botulinum Toxin Therapy provides practical guidance on the use of Botox in a wide variety of disorders. New chapters have been added on the use of botulinum toxin in wound healing, in focal hand dystonia and in thoracic outlet syndrome, as well as others. There are new chapters on the use of botulinum toxins in conjunction with ultrasound guidance. Using clear line-drawings the Manual describes the relevant injection sites for each condition and gives comparative dosage tables for the various formulations of toxins used in different muscle groups. Throughout the emphasis is on technique and the book can be used as both a teaching aid and in bedside guidance. The manual will be of use to neurologists, otolaryngologists, urologists, ophthalmologists, dermatologists, internists, pain management specialists, rehabilitation specialists and plastic surgeons, and any other clinicians discovering the potential of botulinum toxin.

Preface
1. The pretherapeutic history of botulinum toxin Frank J. Erbguth
2. Botulinum toxin: history of clinical development Daniel Truong and Mark Hallett
3. Pharmacology of botulinum neurotoxins Daniel Truong and Mark Hallett
4. Immunological properties of botulinum neurotoxins Hans Bigalke, Dirk Dressler and Jürgen Frevert
5. Treatment of cervical dystonia Daniel Truong, Karen Frei and Cynthia L. Comella
6. Examination and treatment of complex cervical dystonia Gerhard Reichel
7. Ultrasound guidance for botulinim toxin therapy: cervical dystonia Katharine E. Alter
8. Treatment of blepharospasm Carlo Colosimo, Dorina Tiple and Alfredo Berardelli
9. Botulinum toxin in oromandibular dystonia Roongroj Bhidayasiri, Francisco Cardoso and Daniel Truong
10. Treatment of focal hand dystonia Barbara Illowsky Karp, Chandi Prasad Das, Daniel Truong and Mark Hallett
11. Botulinum toxin therapy of laryngeal muscle hyperactivity syndromes Daniel Truong, Arno Olthoff and Rainer Laskawi
12. The use of botulinum toxin in otorhinolaryngology Ranier Laskawi, Arno Olthoff and Oleg Olegovich Ivanov
13. Treatment of hemifacial spasm Karen Frei
14. Spasticity Mayank S. Pathak and Allison Brashear
15. The use of botulinum toxin in spastic infantile cerebral palsy Ann Tilton and H. Kerr Graham
16. The use of botulinum toxin in spasticity using ultrasound guidance Andrea Santamato, Franco Molteni and Pietro Fiore
17. The use of botulinum toxin in tic disorders and essential hand and head tremor Joseph Jankovic
18. Treatment of stiff-person syndrome with botulinum toxin Diana Richardson and Bahman Jabbari
19. Botulinum toxin applications in ophthalmology Peter Roggenkamper and Allan Scott
20. Cosmetic uses of botulinum toxins Joshua Spanogle, Christopher Zachary and Dee Anna Glaser
21. Hyperhidrosis Henning Hamm and Markus K. Naumann
22. Botulinum toxin-A treatment for ischemic digits and chronic pain Michael W. Neumeister and Kelli Webb
23. Botulinum toxin in wound healing Holger G. Gassner
24. Use of botulinum toxin in neuropathic pain Szu-Kuan Yang and Chaur-Jongh Hu
25. The use of botulinum toxin in the management of headache disorders Stephen D. Silberstein
26. The use of botulinum toxin in musculoskeletal pain and arthritis Jasvinder A. Singh
27. Treatment of plantar fasciitis with botulinum neurotoxins Bahman Jabbari and Shivam Om Mittal
28. Use of botulinum toxin in the treatment of low back pain José De Andrés and Gustavo Fabregat
29. Use of botulinum toxin in the treatment of piriformis syndrome Loren M. Fishman and Sarah B. Schmidhofer
30. Ultrasound guided botulinum toxin injections for thoracic outlet syndrome Katharine E. Alter
31. Botulinum toxin in the gastrointestinal tract Vito Annese and Daniele Gui
32. Botulinum toxin application in urological disorders Stefano Carda and Brigitte Schurch
Index