Description

This reference examines the cellular, molecular, and genetic mechanisms involved in airway inflammation, as well as the pathophysiology, epidemiology, and etiology of asthma exploring strategies to prevent cellular injury and oxidative tissue damage, inhibit key inflammatory pathways, and identify disease-specific targets to reduce the induction, progression, and exacerbation of disease.

Table of Contents

PARTIAL CONTENTS
Pathophysiology of Airway Inflammation in Asthma
Paula J. Busse and William W. Busse
Primary Human Lung Cells in the Evaluation of Airway Determination
Tannishia Goggans and Serpil C. Erzurum
Airway pH Homeostasis in Asthma and Other Inflammatory Lung Diseases
John Hunt and Benjamin Gaston
Minitoring of Exhales Breath to Assess Airway Inflammation in Asthma
Peter J. Barnes
The Modulatory Effets of Carbon Monoxide on the Inflammatory Response
Francis Whalen, Augustine M. K. Choi, and Jigme M. Sethi
Reactive Nitrogen Species and Tyrosine Nitration in Airway Inflammation
Albert van der Vliet, Jason P. Eiserich, Brian Morrissey, and Carroll E. Cross
S-Nitrosothiols in Lung Inflammation
Harvey E. Marshall, Loretta G. Que, Jonathan S. Stamler, and Benjamin Gaston
Contribution of Different Nitric Oxide Synthase Isoforms to Allergen-Induced Airway Hyperresponsiveness and Inflammation: Lessons from Murine Models
George T. DeSanctis and El-Bdaoui Haddad
Molecular Mechanisms of Increased Nitric Oxide Airway Inflammation
Weiling Xu and Serpil C. Erzurum
Regulation of Nitric Oxide Synthesis by Inducible Nitric Oxide Synthase
Pawel Kolodziejski, and N. Tony Eissa
Novel Strategies for Selective Inhibition of Inducible Nitric Oxide Synthase
John F. Parkinson
Leukocyte Recruitment in Allergic Pulmonary Inflammation
Bruce S. Bochner
Neutrophil Emigration in the Lungs
Claire M. Doerschuk
Dendritic Cells
A. Karolina Palucka and Jacques Banchereau
The Roles of Mast Cells in Airway Hyper-reactivity, Inflammation, and Remodeling and Immunoregulation in Asthma
John L. Faul and Stephen J. Galli
Mast Cells Exocytosis in Airway Inflammation
Roberto Adachi, Rupesh Nigam, and Burton Dickey