Summary

This seventh edition of Medical Immunology, now in a full-color presentation, continues to provide a succinct clinical review of the human response to infection while being firmly grounded in science. The authors, distinguished and experienced educators, have been able to anticipate readers' conceptual challenges and use illustrations, diagrams, and algorithms throughout to simplify complex concepts. With an emphasis on clinical applications, methodological advances, immunological diseases, and innovative interventions, this tried and true guide navigates readers through state-of-the-sciences technologies and demonstrates their implementation in the day-to-day clinical practice of immunology.

Key Features

Stresses both the basic scientific concepts and clinical correlations to medical practice.
Progresses logically from normal immune function to abnormalities and clinical diseases.
Reviews the diagnosis, pathogenesis, and management of autoimmune diseases in a concise, manageable and visual manner
Continues to be the only current medically-focused immunology text available
Provides a succinct review of human response to infection with a focus on diagnostic and clinical immunology


Table of Contents

Table of Contents

Chapter 1: Introduction

Gabriel Virella

Chapter 2: Leucocytes and Lymphoid Tissues: The Framework of the Immune System

Gabriel Virella

Chapter 3: Major Histocompatibility Complex

Ellen Klohe and Janardan P. Pandey

Chapter 4: The Adaptive Immune Response: Antigens, Lymphocytes and Accessory Cells

Gabriel Virella and John Sleasman

Chapter 5: Immunoglobulins: Structure and Diversity

Gabriel Virella

Chapter 6: Immunoglobulins: Metabolism and Biological Properties

Gabriel Virella

Chapter 7: Genetics of Immunoglobulins: Ontogenic, Biological and Clinical Implications

Janardan P. Pandey

Chapter 8: Antigen-Antibody Reactions

Gabriel Virella

Chapter 9: The Complement System in Health and Disease

Carl Atkinson

Chapter 10: Monocyte and Lymphocyte Membrane Markers: Ontogeny and Clinical Significance

Scott Sugden, Damien Montamat-Sicotte, Karen Yam, Joseph Murphy, Bader Yassine Diab, and Virginia Litwin

Chapter 11: Cell-Mediated Immunity

José C. Crispín And Gabriel Virella

Chapter 12: Adaptive Humoral Immunity and Immunoprophylaxis

Gabriel Virella

Chapter 13: Phagocytic Cells and their Functions

Gabriel Virella And John Sleasman

Chapter 14: Anti-Infectious Innate and Adaptive Immune Responses

Carl Atkinson and Gabriel Virella

Chapter 15: Diagnostic Applications of Immunology

Ajay Grover, Virginia M. Litwin and Gabriel Virella

Chapter 16: Tolerance and Autoimmunity

George C. Tsokos and Gabriel Virella

Chapter 17: Organ-Specific Autoimmune Diseases

G. Virella and George C. Tsokos

Chapter 18: Systemic Lupus Erythematosus

George C. Tsokos

Chapter 19: Rheumatoid Arthritis

George C. Tsokos and Gabriel Virella

Chapter 20: Overview of Hypersensitivity

Gabriel Virella

Chapter 21: IgE-mediated (Immediate) Hypersensitivity

Albert F. Finn, Jr. and Gabriel Virella

Chapter 22: Immunohematology

Armand Glassman and Gabriel Virella

Chapter 23: The Pathogenic Role of Antigen-Antibody Complexes

Gabriel Virella and George C. Tsokos

Chapter 24: Immune System Modulators

Richard Silver and Stephen Elmore

Chapter 25: Transplantation Immunology

Satish N. Nadig and Jane C. Kilkenny

Chapter 26: Tumor Immunology

Juan Carlos Varela

Chapter 27: Lymphocyte and Plasma Cell malignancies

Juan Varela and Gabriel Virella

Chapter 28: Diagnosis of Immune Deficiency Diseases

John W. Sleasman and Gabriel Virella

Chapter 29: Primary Immunodeficiency Diseases

John Sleasman and Gabriel Virella

Chapter 30: AIDS and other Acquired Immunodeficiencies

John Sleasman and Gabriel Virella