Description
Advances in the Canine Cranial Cruciate Ligament, Second Edition presents in-depth, focused, and updated coverage of current knowledge on cruciate ligament rupture, using a multidisciplinary, evidence-based approach.

Presents a state-of-the-art summary of the most recent knowledge on this important cause of lameness in dogs
Led by a highly respected surgeon and researcher, with chapters written by leading experts in the field
Provides an update to the groundbreaking first edition, with six new chapters
Author Information

Peter Muir, BVSc, MVetClinStud, PhD, Diplomate ACVS, ECVS, is the Melita Grunow Family Professor of Companion Animal Health at the University of Wisconsin-Madison School of Veterinary Medicine in Madison, Wisconsin, USA.

Table of Contents
About the Editor

Foreword

Kenneth A. Johnson

Foreword
R. Randy Basinger, ACVS Foundation

Preface
Peter Muir

Acknowledgement

Contributing Authors

Section I: Structure & Function

Introduction
Peter Muir

Chapter 1: Morphology and function of the cruciate ligaments
Hilde de Rooster, Eithne Comerford

Chapter 2: Biomechanics of the cruciate ligaments
Susannah J. Sample

Chapter 3: Cruciate ligament remodeling and repair
Connie S. Chamberlain, Erin E. Crowley, Ray Vanderby Jr.

Chapter 4: Meniscal structure and function
Antonio Pozzi, James L. Cook

Chapter 5: Biomechanics of the normal and cranial cruciate-deficient stifle
Antonio Pozzi, Stanley E. Kim

Section II: Etiopathogenesis of Cruciate Ligament Rupture

Introduction
Peter Muir

Chapter 6: Histology of cranial cruciate ligament rupture
Kei Hayashi

Chapter 7: Genetics of cranial cruciate ligament rupture
Lauren A. Baker, Peter Muir

Chapter 8: Cruciate ligament matrix metabolism and development of laxity
Eithne Comerford

Chapter 9: Morphological risk factors for cruciate ligament rupture
Eithne Comerford

Chapter 10: Role of nitric oxide production and matrix protease activity in cruciate ligament degeneration
David E. Spreng, Simone Forterre

Chapter 11: Role of antibodies to collagen type I and II
Hilde De Rooster, Eithne Comerford

Chapter 12: Synovitis precedes stifle instability associated with cruciate ligament rupture
Jason A. Bleedorn

Chapter 13: Role of synovial immune responses in stifle synovitis
Peter Muir

Section III: Clinical Features

Introduction
Peter Muir

Chapter 14: Epidemiology of cranial cruciate ligament rupture
Lauren A. Baker, Peter Muir

Chapter 15: History and clinical signs of cruciate ligament rupture
Peter Muir

Chapter 16: Partial rupture of the cranial cruciate ligament
Peter Muir

Chapter 17: Caudal cruciate ligament rupture
Peter Muir

Chapter 18: Stress imaging of the stifle
Stanley E. Kim 234

Chapter 19: Stifle ultrasonography
Cristi R. Cook

Chapter 20: Computed tomography (CT) of the stifle
Ingrid Gielen, Henri van Bree

Chapter 21: Magnetic resonance imaging of the stifle
Peter V. Scrivani

Chapter 22: Risk prediction of cruciate ligament rupture using stifle diagnostic imaging
Peter Muir

Section IV: Surgical Treatment

Introduction
Peter Muir

Chapter 23: Arthroscopy and arthrotomy of the stifle
Brian S. Beale, Donald A. Hulse, Antonio Pozzi, Peter Muir

Chapter 24: Joint Lavage
Peter Muir

Chapter 25: Extracapsular stabilization
Selena Tinga, Stanley E. Kim

Chapter 26: Intra-articular repair for cranial cruciate ligament rupture in the dog
Jeffery J. Biskup, Michael G. Conzemius

Chapter 27: Tibial plateau leveling osteotomy
Susan L. Schaefer

Chapter 28: Tibial tuberosity advancement
Randy J. Boudrieau

Chapter 29: Closing cranial wedge osteotomy and triple tibial osteotomy
Simon C. Roe

Chapter 30: Treatment of excessive tibial plateau angle
Michael P. Kowaleski

Chapter 31: Surgical management of cranial cruciate ligament rupture combined with patella luxation
Anke Langenbach, Denis J. Marcellin-Little

Chapter 32: Biomechanics of the cranial cruciate ligament deficient stifle treated by tibial osteotomies
Antonio Pozzi, Stanley E. Kim, Selena Tinga

Chapter 33: Arthroscopic follow-up after surgical stabilization of the stifle
Brian S. Beale, Donald A. Hulse

Chapter 34: Cranial cruciate ligament debridement
David E. Spreng

Chapter 35: Surgical treatment of concurrent meniscal injury
Samuel P. Franklin, James L. Cook, Antonio Pozzi

Chapter 36: Meniscal release
Antonio Pozzi, James L. Cook

Chapter 37: Progression of arthritis after stifle stabilization surgery
Susannah J. Sample

Chapter 38: Clinical outcomes after surgical treatment for cruciate ligament rupture
Mary Sarah Bergh, Steven C. Budsberg

Chapter 39: Success and failure after stifle stabilization surgery
Michael G. Conzemius, Richard B. Evans

Chapter 40: Diagnosis and management of orthopaedic infection after stifle surgery
Noel Moens

Section V: Medical Management of Cruciate Ligament Rupture

Introduction
Peter Muir

Chapter 41: Medical therapy for stifle osteoarthritis
Steven C. Budsberg

Chapter 42: Rehabilitation for dogs with cranial cruciate ligament rupture
Denis J. Marcellin-Little, Courtney J. Arnoldy

Section VI: Future Directions

Introduction
Peter Muir

Chapter 43: Clinical research design and patient-orientated outcomes
Dorothy C. Brown

Chapter 44: Total knee replacement in the dog
Matthew J. Allen, William D. Liska, Valentina Brioschi

Chapter 45: Regenerative medicine and cranial cruciate ligament repair
Gabriel S. Perrone, Martha M. Murray, Patrick Vavken

Chapter 46: Disease-modifying medical and cell-based therapy
Susannah J. Sample, Peter Muir