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Description Handbook of Immunoassay Technologies: Approaches, Performances, and Applications unravels the role of immunoassays in the biochemical sciences. During the last four decades, a wide range of immunoassays has been developed, ranging from the conventional enzyme-linked immunosorbent assays, to the smartphone-based point-of-care formats. The advances in rapid biochemical procedures, novel biosensing schemes, fully integrated lab-on-a-chip platforms, prolonged biomolecular storage strategies, device miniaturization and interfacing, and emerging smart system technologies equipped with personalized mobile healthcare tools are paving the way to next-generation immunoassays, and are all discussed in this comprehensive text.
Immunoassays play a prominent role in clinical diagnostics as they are the eyes of healthcare professionals, helping them make informed clinical decisions via confirmed disease diagnosis, and thus enabling favorable health outcomes. The faster and reliable diagnosis of infections will further control their spread to uninfected persons. Similarly, immunoassays play a prominent role in veterinary diagnostics, food analysis, environmental monitoring, defense and security, and other bioanalytical settings. Therefore, they enable the detection of a plethora of analytes, which includes disease biomarkers, pathogens, drug impurities, environmental contaminants, allergens, food adulterants, drugs of abuse and various biomolecules.
Key Features Provides a valuable increase of understanding of cellular and biomedical functions Gives the most updated resource in the field of immunoassays, providing the comprehensive details of various types of immunoassays that need to be performed in healthcare, and in industrial, environmental and other biochemical settings Discusses all multifarious aspects of immunoassays Describes the immunoassay formats, along with their principle of operation, characteristics, pros and cons, and potential biochemical and bioanalytical applications Provides extensive knowledge and guided insights as detailed by experienced, renowned experts and key opinion makers in the field of immunoassays Readership Researchers in biochemistry, molecular immunology, biomedical engineering, healthcare professionals and other multidisciplinary scientific disciplines. Laboratory researchers and academics who use immunoassay as a tool including pathologists, biochemists, clinical and veterinary chemists, students and researchers in immunology, biochemistry and medicine
Table of Contents Immunoassays: An Overview Antibody Immobilization and Surface Functionalization Chemistries for Immunodiagnostics Monoclonal Antibody Generation by Phage Display: History, State-of-the-art, and Future Bioanalytical Requirements and Regulatory Guidelines for Immunoassays Enzyme-linked Immunoassays Surface Plasmon Resonance-based Immunoassays: Approaches, Performance and Applications Lateral Flow Immunoassays Paper-based Immunoassays Acoustic Wave based Immunoassays Interferometry based Immunoassays Nano- and Micro-Materials based Immunoassays Microcantilever-based sensors Quartz crystal microbalance based sensors Electrochemical Immunosensors: Fundamentals and Applications in Clinical Diagnostics Lab-on-a-Chip Immunoassays Smartphone-based Immunoassays Immunoassays: Future Prospects and Possibilities