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The Liver: Oxidative Stress and Dietary Antioxidants takes a novel approach to the science of oxidative stress in liver disease by recognizing that diseases are multifactorial and oxidative stress is a single component. It highlights oxidative stress in relation to other processes, such as apoptosis, cell signaling and receptor mediated responses, and includes the therapeutic usage of natural antioxidants in the diet and food matrix, along with coverage of pharmacological and natural agents designed to counteract oxidative stress. Written for research scientists, gastroenterologists, food scientists, hepatologists and physicians, this trans-disciplinary guide will help advance medical sciences and enable new preventative and treatment strategies.
Key Features Provides a framework for in-depth analysis of the basic processes of oxidative stress, from molecular biology, to whole organs in relation to the liver Bridges the trans-disciplinary divide between the basic science and mechanisms of liver disease and oxidative stress to advance medical sciences and enable preventative and treatment strategies Contains contributions from leading national and international experts, including those from world renowned institutions Readership Research scientists, gastroenterologists, nutritionists and physicians
Table of Contents Oxidative Stress and the Liver 1. Oxidative stress in hepatitis C infection Birke Bartosch 2. Peroxidases and oxidative stress in fatty livers Lixin Zhu 3. Alterations in nucleocytoplasmic localization of the methionine cycle induced by oxidative stress during liver disease Maria Angeles Pajares 4. Oxidative stress in iron toxicity of the liver Kosha Mehta 5. Cardiac glycosides and oxidative stress in liver cancer Rengul Cetin-Atalay 6. Acetaldehyde effects on cellular redox state. Luis Enrique Gomez-Quiroz 7. The role of glyoxalase-I in oxidant stress of liver damage Marcus Hollenbach 8. Antioxidants 1 Reactive oxygen and nitrogen species and liver ischemia-reperfusion injury an overview Fabienne T.E. Alban, Rowan F. van Golen, Daniel Gyamfi and Michal Heger
Antioxidants and the Liver 9. Antioxidants 2 Reactive oxygen and nitrogen species and liver ischemia-reperfusion injury: role of arginine and glutamine Fabienne T.E. Alban, Rowan F. van Golen, Daniel Gyamfi and Michal Heger 10. Antioxidants 2 Reactive oxygen and nitrogen species and liver ischemia-reperfusion injury: role of lipoic acid Fabienne T.E. Alban, Rowan F. van Golen, Daniel Gyamfi and Michal Heger 11. Oxidative stress as crucial factor in liver disease: Potential Therapeutic effect of Antioxidants H.A. Hassan 12. L-NAME as a synthetic antioxidant in liver injury Adnan Ayhanci, Sila Appak and Mustafa Cengiz 13. Vitamin C, oxidative stress and liver protection Rocio IR Macias 14. Lycopene, liver protection and oxidative stress Kazim Sahin 15. Vitamin E protection against hyperthyroidism-induced liver oxidative stress Paola Venditti 16. Citric acid an antioxidant in liver O. M. E. Abdel-salam 17. Resveratrol and protection in hepatic steatosis: antioxidant effects Maria Puy Portillo 18. Astaxanthin, a marine carotenoid against hepatic oxidative stress: A systematic review. C.V. Anuradha 19. Effects of melatonin as an antioxidant in liver Vijay K. Bharti 20. Antioxidant role of the Mayan fruit canistel (Pouteria campechiana) in liver protection T. Sivasudha 21. Endogenous mitochondrial aldehyde dehydrogenase-2 as an antioxidant in liver Yanfeng Wang 22. Comparing antioxidants in liver disease: L-carnitine, N-acetylcysteine and genistein Kaan Demiroren 23. Coenzyme Q10, liver protection and oxidative stress Farnaz Farsi, Pezhman Alavinejad Sr. and Nava Morshedzadeh 24. Carnosine as a putative antioxidant in usage against liver disease S. Dogru-Abbasoglu 25. Dioscin as a natural saponin and protection in oxidative stress in hepatic fibrosis J. Peng 26. Gallic acid as a putative antioxidant in usage against liver disease Jesus Morlett-Chavez 27. Oleuropein as an antioxidant and liver protection Seung Kew Yoon 28. Garlic and Liver Diseases George L. Tipoe, Jia Xiao, Liangliang Zou, Rui Zhang and Hao Gao