Features

Describes nutritional effects in segments that focus on energy balance, macronutrient quantity and quality, dietary food groups and patterns, and the relationship of these to cardiometabolic health
Features information on novel approaches for promoting metabolic health including behavioral modification, intermittent fasting to achieve calorie restriction, the Paleolithic diet and bariatric surgery
Discusses the relationship of early life nutrition, the gut microbiome and endocrine disruptors to chronic disease, and their modulation by diet
Includes nutritional management strategies for individuals with childhood and adolescent obesity
Provides chapter-specific concluding remarks that summarize the current state of knowledge, and that are aimed at guiding clinicians and healthcare professionals to seek evidence-based practices for promotion of cardiometabolic health

Summary

Nutrition plays a key role in prevention of cardiovascular disease, the leading cause of death worldwide. Diet influences a broad spectrum of cardiometabolic risk factors, notably a cluster including excess adiposity, dyslipidemia, impaired glucose metabolism and high blood pressure. In the face of the rapidly increasing incidence of obesity and diabetes, maintaining cardiometabolic health through adoption of a healthy lifestyle is a top public health priority.

Table of Contents

Contents

Preface

Editors

Contributors

Section I Energy Balance, Adiposity, and

Cardiometabolic Health

Chapter 1 Regulation of Food Intake: The Gut Brain Axis

Surya Panicker Rajeev, Ian W. Seetho, and John P. H. Wilding

Chapter 2 Overeating Behavior and Cardiometabolic Health: Mechanisms and Treatments

Ashley E. Mason and Frederick M. Hecht

Chapter 3 Energy Balance and Regulation of Body Weight: Are All Calories Equal?

Kevin D. Hall

Chapter 4 Diets for Weight Loss

George A. Bray and Patty W. Siri-Tarino

Chapter 5 Weight Loss by Surgical Intervention: Nutritional Considerations and Influence

on Health

Karim Kheniser and Sangeeta Kashyap

Chapter 6 Physical Activity and Cardiometabolic Health

Andrea M. Brennan and Robert Ross

Chapter 7 Diet as a Potential Modulator of Body Fat Distribution

Sofia Laforest, Genevi ve B. Marchand, and Andr Tchernof

Chapter 8 Nutritional Considerations for Cardiometabolic Health in Childhood and

Adolescent Obesity

Elizabeth Prout Parks, Jennifer Panganiban, Stephen R. Daniels,

and Julie Brothers

Chapter 9 Aging and Cardiovascular Disease: Lessons from Calorie Restriction

Jasper Most and Leanne M. Redman

Section II Dietary Fats and Cardiometabolic Health

Chapter 10 Omega-3 and Omega-6 Fatty Acids: Roles in Cardiometabolic Disease

William S. Harris

Chapter 11 Evolving Role of Saturated Fatty Acids

Patty W. Siri-Tarino and Ronald M. Krauss

Chapter 12 Effects of Dietary Trans Fatty Acids on Cardiovascular Risk

Ronald P. Mensink

Section III Dietary Carbohydrates and

Cardiometabolic Health

Chapter 13 Epidemiologic and Mechanistic Studies of Sucrose and Fructose in Beverages

and Their Relation to Obesity and Cardiovascular Risk

George A. Bray

Chapter 14 Effects and Mechanisms of Fructose-Containing Sugars in the Pathophysiology

of Metabolic Syndrome

Kimber L. Stanhope and Peter J. Havel

Chapter 15 Dietary Carbohydrate Restriction in the Management of NAFLD and

Metabolic Syndrome

Grace Marie Jones, Kathleen Mulligan, and Jean-Marc Schwarz

Chapter 16 Dietary Starches and Grains: Effects on Cardiometabolic Risk

Nathalie Bergeron and Ronald M. Krauss

Section IV Dietary Protein and Cardiometabolic Health

Chapter 17 Interaction of Dietary Protein and Energy Balance

Eveline A. Martens, Richard D. Mattes, and Margriet S. Westerterp-Plantenga

Chapter 18 A Protein-Centric Perspective for Skeletal Muscle Metabolism and

Cardiometabolic Health

Donald K. Layman

Chapter 19 Protein Sources, CVD, Type 2 Diabetes, and Total MortalityPeter Clifton

Chapter 20 Consumption of Foods, Food Groups, and Cardiometabolic Risk

Edward Yu and Frank B. Hu

Chapter 21 Dietary Patterns and Cardiometabolic Disease

Elizabeth M. Cespedes Feliciano and Frank B. Hu

Chapter 22 The Mediterranean Diet to Prevent Type 2 Diabetes and Cardiovascular Disease

Michel de Lorgeril

Chapter 23 The DASH Diet

Catherine M. Champagne

Chapter 24 Nut Consumption and Coronary Heart Disease (CHD) Risk and Mortality

Christina Link, Alyssa Tindall, Jordi Salas-Salvadó, Caitlin Lynch, and

Penny Kris-Etherton

Chapter 25 Dairy Product Consumption, Dairy Fat, and Cardiometabolic Health

Benoît Lamarche

Chapter 26 Paleolithic Diets

Staffan Lindeberg, Maelán Fontes Villalba, Pedro Carrera-Bastos, and

Lynda Frassetto

Chapter 27 Fasting Intermittently or Altering Meal Frequency: Effects on Plasma Lipids

John F. Trepanowski and Krista A. Varady

Section VI Other Nutritional Influences

of Cardiometabolic Health

Chapter 28 Early-Life Nutrition, Epigenetics, and Later Cardiometabolic Health

Mark H. Vickers, Clare M. Reynolds, and Clint Gray

Chapter 29 Gene Diet Interactions

Silvia Berciano and Jose M. Ordovas

Chapter 30 Gut Microbiome: Its Relationship to Health and Its Modulation by Diet

Brian J. Bennett and Katie A. Meyer

Chapter 30 Gut Microbiome: Its Relationship to Health and Its Modulation by Diet

Brian J. Bennett and Katie A. Meyer

Chapter 31 Alcohol: Associations with Blood Lipids, Insulin Sensitivity, Diabetes,

Clotting, CVD, and Total Mortality

Charlotte Holst and Janne Schurmann Tolstrup

Chapter 32 Endocrine Disrupting Chemicals, Obesogens, and the Obesity Epidemic

Raquel Chamorro-Garcia and Bruce Blumberg

Index