Features

Histological images and their quantitative examination by cytometry presented side by side
Over 350 high-quality images
Based on WHO classification of hematopoietic tumors
Detailed and up-to-date criteria for diagnosis
Systematic approach including basic cases and complicated problem areas
Summary

This third edition is the product of the author's 25 years of experience with flow cytometry; although it covers the wide spectrum of hematopoietic tumors, the focus remains on most important clinical diagnoses, such as acute promyelocytic leukemia, identification of blasts, identification of clonal B-cell population, differentiating mature versus immature T-cell proliferations, deferential diagnosis between hematogones and B-ALL or distinction between chronic and acute monocytic proliferations. All hematopathologists and neoplastic hematologists will find this an important resource for keeping up to date with developments in clinical practice.

Table of Contents

Preface to the third edition. Abbreviations. Introduction. Gating strategies. Classification of hematopoietic neoplasms. Identification of clonal B-cell population. Identification of atypical T-cell population. Identification of myeloblasts. Identification of B-lymphoblasts. Identification of T-lymphoblasts. Antigen expression during myeloid and lymphoid maturation. Identification of myelodysplastic syndrome by flow cytometry. Phenotypic markers. Morphologic-flow cytometric correlation. Molecular-flow cytometric correlation. Flow cytometry limitations. Phenotypic classification of B-cell lymphoproliferations. Mature B-cell lymphoproliferations. Plasma cell neoplasms. Mature T/NK-cell lymphoproliferations. Hodgkin lymphoma. B-lymphoblastic leukemia (B-ALL). T-lymphoblastic leukemia (T-ALL). Myelodysplastic syndromes. Chronic myelomonocytic leukemia and other myelodysplastic/myeloproliferative neoplasms. Myeloproliferative neoplasms. Acute myeloid leukemia: introduction. Acute myeloid leukemia: recurrent genetic changes. Acute myeloid leukemia: not otherwise specified. Other neoplasms.