More than 300 diagnoses that are delineated, referenced, and lavishly illustrated highlight the third edition of this bestselling reference. World-renowned authority Dr. Anne G. Osborn and her expert author team of Drs. Karen L. Salzman and Miral D. Jhaveri provide carefully updated information in a concise, bulleted format, keeping you current with new disease entities and syndromes, MR imaging techniques and applications, and pathology relevant to brain imaging. Succinct text, outstanding illustrations, and up-to-date content make this title a must-have reference for neuroradiologists, general radiologists, neurologists, and neurosurgeons.

Key Features
Concise, bulleted text provides efficient information on more than 300 diagnoses that are clearly illustrated with 2,500 superb images

New to this Edition
Meticulously updated throughout, with new diagnoses and hundreds of new images that provide the most current information in the field.
Expert guidance on CLIPPERS, second-impact syndrome in trauma, perfusion MR for tumor characterization, susceptibility-weighted imaging in stroke and brain bleeds, and molecular markers in brain tumor classification and grading.
Updated coverage of brain trauma addresses newly recognized entities, techniques and imaging for rapid stroke triage, and functional imaging and dementia diagnosis.

Author Information
By Anne G Osborn, MD, FACR, Distinguished Professor of Radiology, William H. and Patricia W. Child Presidential Endowed Chair in Radiology, University of Utah School of Medicine, GE Healthcare; Visiting Professor in Diagnostic Imaging, Armed Forces Institute of Pathology, Salt Lake City, Utah ; Karen L. Salzman, MD, Professor of Radiology, Leslie W. Davis Endowed Chair in Neuroradiology, University of Utah School of Medicine, Salt Lake City, Utah ; Miral D Jhaveri, MD, Associate Professor, Director of Neuroradiology, Department of Diagnostic Radiology & Nuclear Medicine, Rush University Medical Center, Chicago, Illinois and A. James Barkovich, MD, Professor of Radiology, Neurology, Pediatrics, and Neurosurgery, Department of Radiology and Biomedical Imaging, University of California San Francisco Hospital and UCSF-Benioff Children's Hospital, San Francisco, California

Pathology-based Diagnoses
Congenital Malformations
1 Congenital Malformations Overview
Hindbrain Herniations, Miscellaneous Malformations
2 Chiari 1
3 Chiari 2
4 Chiari 3
5 Callosal Dysgenesis
6 Lipoma
Hindbrain Malformations
7 Dandy-Walker Continuum
8 Rhombencephalosynapsis
9 Unclassified Cerebellar Dysplasias
10 Molar Tooth Malformations (Joubert)
Disorders of Diverticulation/Cleavage
11 Holoprosencephaly
12 Holoprosencephaly Variants
13 Syntelencephaly (Middle Interhemispheric Variant)
14 Septooptic Dysplasia
Malformations of Cortical Development
15 Microcephaly
16 Congenital Muscular Dystrophy
17 Heterotopic Gray Matter
18 Polymicrogyria
19 Lissencephaly
20 Schizencephaly
21 Hemimegalencephaly
Familial Tumor/Neurocutaneous Syndromes
22 Neurofibromatosis Type 1
23 Neurofibromatosis Type 2
24 von Hippel-Lindau
25 Tuberous Sclerosis Complex
26 Sturge-Weber Syndrome
27 Meningioangiomatosis
28 Basal Cell Nevus Syndrome
29 Hereditary Hemorrhagic Telangiectasia
30 Encephalocraniocutaneous Lipomatosis
31 Lhermitte-Duclos Disease
32 Neurocutaneous Melanosis
33 Aicardi Syndrome
34 Li-Fraumeni Syndrome
Trauma
35 Trauma Overview
Primary Effects of CNS Trauma
36 Scalp and Skull Injuries
37 Missile and Penetrating Injury
38 Epidural Hematoma, Classic
39 Epidural Hematoma, Variant
40 Acute Subdural Hematoma
41 Subacute Subdural Hematoma
42 Chronic Subdural Hematoma
43 Traumatic Subarachnoid Hemorrhage
44 Cerebral Contusion
45 Diffuse Axonal Injury (DAI)
46 Subcortical Injury
47 Pneumocephalus
48 Child Abuse
Secondary Effects of CNS Trauma
49 Intracranial Herniation Syndromes
50 Post-Traumatic Brain Swelling
51 Traumatic Cerebral Ischemia/Infarction
52 Brain Death
53 Second Impact Syndrome
54 Traumatic Arterial Dissection
55 Traumatic Carotid Cavernous Fistula
56 Chronic Traumatic Encephalopathy
Subarachnoid Hemorrhage and Aneurysms
57 Subarachnoid Hemorrhage & Aneurysms Overview
Subarachnoid Hemorrhage
58 Aneurysmal Subarachnoid Hemorrhage
59 Perimesencephalic Nonaneurysmal SAH
60 Convexal Subarachnoid Hemorrhage
61 Superficial Siderosis
Aneurysms
62 Saccular Aneurysm
63 Pseudoaneurysm
64 Vertebrobasilar Dolichoectasia
65 ASVD Fusiform Aneurysm
66 Non-ASVD Fusiform Aneurysm
67 Blood Blister-like Aneurysm
Stroke
68 Stroke Overview
Nontraumatic Intracranial Hemorrhage
69 Evolution of Intracranial Hemorrhage
70 Spontaneous Nontraumatic Intracranial Hemorrhage
71 Hypertensive Intracranial Hemorrhage
72 Remote Cerebellar Hemorrhage
73 Germinal Matrix Hemorrhage
Atherosclerosis and Carotid Stenosis
74 Intracranial Atherosclerosis
75 Extracranial Atherosclerosis
76 Arteriolosclerosis
Nonatheromatous Vasculopathy
77 Aberrant Internal Carotid Artery
78 Persistent Carotid Basilar Anastomoses
79 Sickle Cell Disease, Brain
80 Moyamoya
81 Primary Arteritis of the CNS
82 Miscellaneous Vasculitis
83 Reversible Cerebral Vasoconstriction Syndrome
84 Vasospasm
85 Systemic Lupus Erythematosus
86 Cerebral Amyloid Disease
87 CADASIL
88 Behcet Disease
89 Susac Syndrome
90 Fibromuscular Dysplasia
Cerebral Ischemia and Infarction
91 Hydranencephaly
92 White Matter Injury of Prematurity
93 Term Hypoxic Ischemic Injury
94 Adult Hypoxic Ischemic Injury
95 Hypotensive Cerebral Infarction
96 Childhood Stroke
97 Dyke-Davidoff-Masson Syndrome
98 Acute Cerebral Ischemia-Infarction
99 Subacute Cerebral Infarction
100 Chronic Cerebral Infarction
101 Multiple Embolic Cerebral Infarctions
102 Fat Emboli Cerebral Infarction
103 Lacunar Infarction
104 Cerebral Hyperperfusion Syndrome
105 Dural Sinus Thrombosis
106 Cortical Venous Thrombosis
107 Deep Cerebral Venous Thrombosis
108 Dural Sinus and Aberrant Arachnoid Granulations
Vascular Malformations
109 Vascular Malformations Overview
CVMs with AV Shunting
110 Arteriovenous Malformation
111 Dural AV Fistula
112 Vein of Galen Aneurysmal Malformation
CVMs without AV Shunting
113 Developmental Venous Anomaly
114 Sinus Pericranii
115 Cavernous Malformation
116 Capillary Telangiectasia
Neoplasms
117 Neoplasms Overview
Astrocytic Tumors, Infiltrating
118 Low-Grade Diffuse Astrocytoma
119 Anaplastic Astrocytoma
120 Glioblastoma
121 Gliosarcoma
122 Gliomatosis Cerebri
Astrocytic Tumors, Localized
123 Pilocytic Astrocytoma
124 Pilomyxoid Astrocytoma
125 Pleomorphic Xanthoastrocytoma
126 Subependymal Giant Cell Astrocytoma
Oligodendroglial and Miscellaneous Tumors
127 Oligodendroglioma
128 Anaplastic Oligodendroglioma
129 Astroblastoma
130 Chordoid Glioma of the Third Ventricle
131 Angiocentric Glioma
Ependymal Tumors
132 Infratentorial Ependymoma
133 Supratentorial Ependymoma
134 Subependymoma
Choroid Plexus Tumors
135 Typical Choroid Plexus Papilloma
136 Choroid Plexus Carcinoma
Neuronal and Mixed Neuronal-Glial Tumors
137 Ganglioglioma
138 Desmoplastic Infantile Tumors
139 DNET
140 Central Neurocytoma
141 Extraventricular Neurocytoma
142 Cerebellar Liponeurocytoma
143 Papillary Glioneuronal Tumor
144 Rosette-Forming Glioneuronal Tumor
Pineal Parenchymal Tumors
145 Pineocytoma
146 Pineal Parenchymal Tumor of Intermediate Differentiation
147 Pineoblastoma
148 Papillary Tumor of the Pineal Region
Embryonal and Neuroblastic Tumors
149 Medulloblastoma
150 Supratentorial PNET
151 Atypical Teratoid-Rhabdoid Tumor
152 Metastatic Neuroblastoma
Tumors of Cranial/Peripheral Nerves
153 Nonvestibular Schwannoma
154 Neurofibroma
Blood Vessel and Hemopoietic Tumors
155 Hemangioblastoma
156 Hemangiopericytoma
157 Primary CNS Lymphoma
158 Intravascular (Angiocentric) Lymphoma
159 Leukemia
Germ Cell Tumors
160 Germinoma
161 Teratoma
162 Miscellaneous Malignant Germ Cell Neoplasms
Metastatic Tumors and Remote Effects of Cancer
163 Parenchymal Metastases
164 Miscellaneous Intracranial Metastases
165 Metastatic Intracranial Lymphoma
166 Paraneoplastic Syndromes
Primary Nonneoplastic Cysts
167 Primary Nonneoplastic Cysts Overview
168 Arachnoid Cyst
169 Colloid Cyst
170 Dermoid Cyst
171 Epidermoid Cyst
172 Neuroglial Cyst
173 Periventricular Cyst
174 Choroid Fissure Cyst
175 Hippocampal Sulcus Remnant Cysts
176 Enlarged Perivascular Spaces
177 Pineal Cyst
178 Choroid Plexus Cyst
179 Ependymal Cyst
180 Porencephalic Cyst
181 Neurenteric Cyst
182 Nonneoplastic Tumor-associated Cysts
Infectious, Inflammatory, and Demyelinating Disease
183 CNS Infectious Disease Overview
Congenital/Neonatal Infections
184 TORCH Infections, Overview
185 Congenital CMV
186 Congenital HIV
187 Neonatal Herpes Encephalitis
Acquired Infections
188 Group B Streptococcal Meningitis
189 Citrobacter Meningitis
190 Meningitis
191 Abscess
192 Ventriculitis
193 Empyema
194 Herpes Encephalitis
195 Miscellaneous Encephalitis
196 West Nile Virus Encephalitis
197 HHV-6 Encephalitis
198 Cerebellitis
199 Rasmussen Encephalitis
200 Subacute Sclerosing Panencephalitis
201 Tuberculosis
202 Neurocysticercosis
203 Hydatid Disease
204 Amebic Disease
205 Cerebral Malaria
206 Miscellaneous Parasites
207 Fungal Diseases
208 Rickettsial Diseases
209 Lyme Disease
210 Acquired HIV Encephalitis
211 Acquired Toxoplasmosis
212 Acquired CMV
213 Cryptococcosis
214 Progressive Multifocal Leukoencephalopathy (PML)
215 Immune Reconstitution Inflammatory Syndrome (IRIS)
216 HIV/AIDS, Miscellaneous Manifestations
Inflammatory and Demyelinating Disease
217 Multiple Sclerosis
218 Neuromyelitis Optica
219 ADEM
220 AHLE
221 Clippers
Inherited Metabolic/Degenerative Disorders
222 Inherited Metabolic Disorders Overview
Normal Variants
223 Hypomyelination
Mitochondrial Disorders
224 Leigh Syndrome
225 MELAS
226 Kearns-Sayre Syndrome
Lysosomal Disorders
227 Mucopolysaccharidoses
228 Gangliosidosis (GM2)
229 Metachromatic Leukodystrophy (MLD)
230 Krabbe
231 Fabry Disease
Peroxisomal Disorders
232 Zellweger Syndrome Spectrum
233 X-Linked Adrenoleukodystrophy
234 Other Peroxisomal Disorders
Organic and Aminoacidopathies
235 Maple Syrup Urine Disease
236 Urea Cycle Disorders
237 Glutaric Aciduria Type 1
238 Canavan Disease
239 Alexander Disease
240 Miscellaneous Organic/Aminoacidopathies
Miscellaneous
241 Megalencephaly with Leukoencephalopathy and Cysts (MLC)
242 Neurodegeneration with Brain Iron Accumulation (NBIA)
243 PKAN
244 Huntington Disease
245 Wilson Disease
Acquired Toxic/Metabolic/Degenerative Disorders
246 Acquired Toxic/Metabolic Disorders Overview
Toxic, Metabolic, Nutritional, Systemic Diseases with CNS Manifestations
247 Pediatric Hypoglycemia
248 Adult Hypoglycemia
249 Kernicterus
250 Thyroid Disorders
251 Parathyroid Disorders
252 Fahr Disease
253 Alcoholic Encephalopathy
254 Hepatic Encephalopathy
255 Acute Hypertensive Encephalopathy, PRES
256 Chronic Hypertensive Encephalopathy
257 Idiopathic Intracranial Hypertension
258 Carbon Monoxide Poisoning
259 Drug Abuse
260 Methanol Poisoning
261 Cyanide Poisoning
262 Osmotic Demyelination Syndrome
263 Radiation and Chemotherapy
264 Pseudoprogression
265 Pseudoresponse
266 Mesial Temporal Sclerosis
267 Status Epilepticus
268 Transient Global Amnesia (TGA)
Dementias and Degenerative Disorders
269 Normal Aging Brain
270 Alzheimer Disease
271 Vascular Dementia
272 Frontotemporal Lobar Degeneration
273 Dementia with Lewy Bodies
274 Creutzfeldt-Jakob Disease (CJD)
275 Parkinson Disease
276 Multiple System Atrophy
277 Corticobasal Degeneration
278 Progressive Supranuclear Palsy
279 Amyotrophic Lateral Sclerosis (ALS)
280 Wallerian Degeneration
281 Crossed Cerebellar Diaschisis
282 Hypertrophic Olivary Degeneration
Anatomy-based Diagnoses
Ventricles and Cisterns
283 Ventricles and Cisterns Overview
Normal Variants
284 Cavum Septi Pellucidi (CSP)
285 Cavum Velum Interpositum (CVI)
286 Enlarged Subarachnoid Spaces
Hydrocephalus
287 Intraventricular Obstructive Hydrocephalus
288 Extraventricular Obstructive Hydrocephalus
289 Aqueductal Stenosis
290 Normal Pressure Hydrocephalus
291 CSF Shunts and Complications
Sella and Pituitary
292 Sella and Pituitary Overview
Congenital
293 Pituitary Anomalies
294 Tuber Cinereum Hamartoma
295 Rathke Cleft Cyst
Neoplasms
296 Pituitary Microadenoma
297 Pituitary Macroadenoma
298 Pituitary Apoplexy
299 Craniopharyngioma
300 Pituicytoma
301 Spindle Cell Oncocytoma
302 Granular Cell Tumor
Miscellaneous
303 Empty Sella
304 Pituitary Hyperplasia
305 Lymphocytic Hypophysitis
CPA-IAC
306 CPA-IAC Overview
Congenital
307 Lipoma, CPA-IAC
308 Epidermoid Cyst, CPA-IAC
309 Arachnoid Cyst, CPA-IAC
Inflammatory
310 Bell Palsy
Vascular
311 Trigeminal Neuralgia
312 Hemifacial Spasm
Neoplasms
313 Vestibular Schwannoma
314 Meningioma, CPA-IAC
315 Metastases, CPA-IAC
Skull, Scalp, and Meninges
316 Skull, Scalp, & Meninges Overview
Congenital
317 Congenital Calvarial Defects
318 Craniostenoses
319 Cephalocele
320 Atretic Cephalocele
Trauma
321 Leptomeningeal Cyst ("Growing Fracture")
322 Intracranial Hypotension
Nonneoplastic and Tumor-like Disorders
323 Ig G4 Related Diseases
324 Fibrous Dysplasia
325 Paget Disease
326 Extramedullary Hematopoiesis
327 Thick Skull
328 Langerhans Cell Histiocytosis, Skull and Brain
329 Neurosarcoid
330 Miscellaneous Histiocytoses
331 Sebaceous Cyst
Neoplasms
332 Meningioma
333 Atypical and Malignant Meningioma
334 Miscellaneous Benign Mesenchymal Tumors
335 Miscellaneous Malignant Mesenchymal Tumors
336 Calvarial Hemangioma
337 Dura/Venous Sinuses Hemangioma
338 Myeloma
339 Skull and Meningeal Metastases