Completely updated and revised, Clinical Tuberculosis continues to provide the TB practitioner whether in public health, laboratory science or clinical practice with a synoptic and definitive account of the latest methods of diagnosis, treatment and control of this challenging and debilitating disease.

New in the Fifth Edition:

Gamma interferon-based blood tests for the screening of latent infection
New molecular techniques for diagnosing the species of Mycobacterium and identifying the gene for rifampicin resistance
Updated content on the human immune response to the tubercle bacillus
Details of microscopic observation for drug sensitivity
Expanded sections on the management and control of TB both locally and globally
A wealth of new diagrams and clinical photographs
Access to companion eBook included with the print book

Background

The History of Tuberculosis from Earliest Times to the Development of Drugs; Charlotte A. Roberts and Jane E. Buikstra

Epidemiology; Ted Cohen and Christopher Dye

Pathology and Immunology

Mycobacterium tuberculosis The Organism; John M. Grange

Genotyping and Its Implications for Transmission Dynamics and Tuberculosis Control; Laura Anderson

Histopathology; Helen C. Wainwright

Diagnosis

Immunodiagnosis of Tuberculosis Infection; Ajit Lalvani, Manish Pareek and Katrina Pollock

Diagnosis of Tuberculosis; Luis E. Cuevas

Tuberculosis Clinical Immunology; Robert S. Wallis

Clinical Aspects

Respiratory Tuberculosis; Aravind Ponnuswamy

Tuberculosis of the Central Nervous System; Guy Thwaites

Non-Respiratory Tuberculosis; Peter Ormerod

Tuberculosis in Childhood; Delane Shingadia

Treatment

Clinical Pharmacology of the Anti-Tuberculosis Drugs; Abdullah AlSultan and Charles A. Peloquin

Chemotherapy Including Drug-Resistant Therapy; Gerry Davies

New Developments in Drug Treatment; Alexander S. Pym

The Surgical Management of Tuberculosis and Its Complications; Richard S. Steyn

Tuberculosis in Special Situations

Human Immunodeficiency Virus and Tuberculosis Co-Infection; Keertan Dheda and Greg Calligaro

Tuberculosis and Migration; Einar Heldal

Tuberculosis and Poverty: A Clinical Perspective; S. Bertel Squire

Multi- and Extreme Drug Resistance: The Experience of India; Zarir F. Udwadia

Prevention

Preventive Therapy; Jean-Pierre Zellweger

Bacille Calmette Guerin and Prospects for New Vaccines against Tuberculosis; Helen McShane

Control

Community Approaches to Tuberculosis Treatment; Kwonjune J. Seung and Michael L. Rich

Control of Tuberculosis in Low-incidence Countries; Ibrahim Abubakar and Robert Aldridge

Control of Tuberculosis in High-Prevalence Countries; Jayant N. Banavaliker

The Role of the Tuberculosis Nurse Specialist; Christine E. Bell

Related Aspects

Non-Tuberculous Mycobacteria; Jakko van Ingen

Animal Tuberculosis; Dirk U. Pfeiffer and Leigh A. L. Corner

Conclusions

Conclusions