A true diagnostic guide filled with valuable medical information
Full of unexpected tips and pearls
Useful for both practicing physicians and students
Which disease should you consider when a young adult has localized bone pain that is dramatically relieved by aspirin? What is sometimes the only physical manifestation of bulimia nervosa? These so-called "old fashioned" historical clues and physical signs are not only part of our medical heritage; their deployment can often spell the difference between prompt clinical diagnosis versus a costly investigative odyssey. Often overlooked with today's emphasis on laboratory testing, a diagnostic pearl such as knowing that a diabetic patient with peripheral neuropathy may actually have metformin-induced vitamin B12 deficiency can be a shortcut to disease recognition.

Diagnostic Principles and Applications presents selected literature-based facts and diagnostic insights to help clinicians provide better-informed clinical assessments, avoid medical misadventures, and prepare for their board examinations. The chapters cover:

Classic diagnostic pearls
Red flag symptoms and signs of serious illness
Bellwether disease indications allowing an occasional early, preemptive diagnosis
Counterintuitive clinical manifestations of disease
Curious clues to specific diagnoses.

TABLE OF CONTENTS
Undifferentiated problems.- Infants and children.- The nervous system.- The eye.- The ear, nose and throat.- The cardiovascular system.- The respiratory system.- The digestive system.- The kidney and male genitourinary system.- The female reproductive system.- The musculoskeletal system.- The skin and subcutaneous tissues.- The endocrine and metabolic systems.- Blood and hematologic system.- Infections and infestations.- Mental health problems.- Laboratory and imaging diagnostics.- Appendix: Glossary of statistical terms used in this book.