Continued geographic expansion of dengue viruses and their mosquito vectors has seen the magnitude and frequency of epidemic dengue/dengue hemorrhagic fever (DF/DHF) increase dramatically. More than 200,000,000 infections and over 2 million cases of DHF occur annually, and dengue is one of the most important emerging tropical diseases in the world. Its dramatically increased incidence and geographic expansion is driven by unprecedented urbanization in tropical developing countries, globalization and lack of public health infrastructure to prevent and control epidemic disease. Recent exciting research on dengue viruses has resulted in major advances in our understanding of all aspects of the biology of these viruses. This updated second edition of Dengue and Dengue Hemorrhagic Fever brings together leading research and clinical scientists to review the latest findings on dengue virus biology, epidemiology, entomology, therapeutics, vaccinology and clinical management

1. Dengue: How a Mosquito-Borne Viral Disease Became a Global Public Health Challenge 2. Epidemiology of Dengue 3. Disease Burden of Dengue 4. Dengue Surveillance 5. Dengue in Travelers 6. Dengue Models 7. Transmission Models 8. Clinical Features of Dengue 9. Neurologic Complications 10. Clinical Management of DHF 11. Laboratory Diagnosis of Dengue 12. Dengue Pathogenesis - Host Factors 13. Dengue Pathogenesis - Viral Factors 14. Acquired Immune Responses to Dengue Infection 15. Innate Immune Responses to Dengue Infection 16. Pathology 17. Anti-Dengue Drugs 18. Taxonomy and Evolutionary Relationship of Flaviviruses 19. Molecular Virology of Dengue 20. The Structural Biology of Dengue Virus 21. Role of Non-Structural Dengue Proteins 22. Virus-Human Interaction 23. Virus-Mosquito Interaction 24. Animal Models 25. Vector Bionomics 26. Factors Influencing Virus Transmission 27. Vector Control 28. Vector Control - New Approaches 29. Biologic Control 30. Vaccine Development 31. Virus Neutralization And Surrogates Of Protection