Delay and mistakes in the diagnosis of inherited metabolic diseases may have devastating consequences. Reference laboratory data are scattered and clinical descriptions of rare conditions are hard to locate. This book describes 298 disorders, grouped into 35 chapters according to the type of condition. Within each group of disorders, chapters provide tables of pertinent clinical findings as well as reference and pathological values for crucial metabolites. Relevant metabolic pathways and diagnostic flow charts are included. There are four indices to make the book as user-friendly as possible: Disorders index, Signs and symptoms index, Organs index, and Tests index. The Physician's Guide provides paediatricians and other physicians with a unique aid to help them select the correct diagnosis from a bewildering array of complex clinical and laboratory data. The book includes a CD-ROM with search function.

System requirements: Microsoft Windows 95 OSR 2.0, Windows 98 SE, Windows Millennium Edition, Windows NT 4.0 with Service Pack 5, Windows 2000, or Windows XP: - Intel Pentium processor or compatible - 64 MB of RAM - 24 MB of available hard-diskspace. Mac OS software version 8.6, 9.0.4, 9.1, or Mac OS X: - PowerPC(R) processor - 64 MB of RAM - 24 MB of available hard-disk space. The program also runs under UNIX computers when the free Adobe Acrobat Reader is installed. You maydownload the latest version of Adobe Acrobat Reader from http://www.adobe.com/products/acrobat/readstep2.html.